WARNING

Endacof AC is a combination medication containing brompheniramine and codeine. Here are some brief risks associated with taking this medication:

• Drowsiness and Sedation: Both brompheniramine and codeine can cause drowsiness and sedation, which may impair your ability to operate machinery or drive safely.
• Respiratory Depression: Codeine, being an opioid, can suppress the respiratory system at high doses, leading to shallow breathing or even respiratory arrest, especially in those who are opioid-naive or with certain respiratory conditions.
• Addiction and Dependence: Codeine is an opioid and carries a risk of addiction and dependence, particularly with prolonged use or at high doses. This risk increases in individuals with a history of substance abuse or addiction.
• Drug Interactions: Both brompheniramine and codeine can interact with other medications, including certain antidepressants, sedatives, and other opioids, potentially leading to serious side effects or reduced effectiveness.
• Allergic Reactions: Some individuals may be allergic to brompheniramine or codeine, which can lead to allergic reactions ranging from mild rash to severe anaphylaxis.
• Gastrointestinal Effects: Codeine can cause constipation, which may be severe in some individuals. Additionally, brompheniramine may cause gastrointestinal upset or nausea in some people.
• Central Nervous System Effects: Both brompheniramine and codeine can affect the central nervous system, leading to symptoms such as dizziness, confusion, or blurred vision.
• Overdose: Taking too much Endacof AC can lead to overdose, which may manifest as extreme sedation, respiratory depression, coma, or even death.

It’s essential to use Endacof AC only as directed by a healthcare professional and to be aware of these potential risks. If you experience any concerning symptoms while taking this medication, seek medical attention promptly.

Why is this medication prescribed?

Endacof AC, containing brompheniramine and codeine, is typically prescribed for the relief of symptoms associated with allergies and colds, such as sneezing, runny or stuffy nose, itching, watery eyes, and cough. Brompheniramine is an antihistamine that helps alleviate allergy symptoms, while codeine is a cough suppressant that helps relieve coughing.

How should this medicine be used?

Here’s how it should be used:

• Dosage Instructions: Follow your doctor’s prescription carefully. The dosage may vary based on your age, medical condition, and response to treatment. Do not exceed the recommended dosage without consulting your doctor.
• Formulation: Endacof DM is available in various formulations such as tablets, capsules, or liquid syrup. Use the formulation prescribed by your doctor.
• Administration:
  • Tablets or capsules: Swallow them whole with a full glass of water. Do not crush or chew extended-release tablets unless instructed by your doctor.
  • Liquid syrup: Shake the bottle well before measuring each dose. Use the measuring device provided with the medication to ensure accurate dosage.
• Frequency: Take Endacof DM as directed by your doctor. It’s typically taken every 4 to 6 hours as needed for symptom relief. Do not take more frequently than prescribed.
• Avoid Alcohol: Avoid consuming alcohol while taking Endacof DM, as it may increase the risk of side effects such as drowsiness or dizziness.
• Food Interaction: You can take Endacof DM with or without food. However, taking it with food may help reduce stomach upset.
• Storage: Store Endacof DM at room temperature away from moisture and heat. Keep it out of reach of children.
• Duration of Use: Use Endacof DM for the shortest duration necessary to relieve your symptoms. Do not continue using it for longer than recommended unless directed by your doctor.
• Medical Conditions and Drug Interactions: Inform your doctor about any medical conditions you have and any other medications you are taking, including prescription, over-the-counter, vitamins, and herbal supplements. Certain medical conditions and drug interactions may affect the safety and effectiveness of Endacof DM.
• Side Effects: Be aware of potential side effects such as drowsiness, dizziness, dry mouth, blurred vision, constipation, or difficulty urinating. If you experience any severe or persistent side effects, contact your doctor promptly.

Always consult your healthcare provider or pharmacist if you have any questions or concerns about how to use Endacof DM.

Other uses for this medicine

Other uses of Endacof AC may include off-label uses as determined by your doctor. However, it’s essential to use this medication only as prescribed and directed.

What special precautions should I follow?

As for special precautions when using Endacof AC, it’s crucial to consider the following:

• Medical History: Before taking Endacof AC, inform your healthcare provider about any medical conditions you have, especially respiratory conditions (such as asthma or COPD), liver or kidney disease, history of substance abuse or addiction, mental health disorders, or any allergies.
• Pregnancy and Breastfeeding: Endacof AC should be used with caution during pregnancy and breastfeeding. Consult with your healthcare provider before using this medication if you are pregnant, planning to become pregnant, or breastfeeding.
• Interaction with Other Medications: Inform your doctor about all the medications, supplements, and herbal products you are currently taking, as Endacof AC may interact with certain drugs, including other opioids, sedatives, tranquilizers, monoamine oxidase inhibitors (MAOIs), and certain antidepressants. Avoid alcohol consumption while taking this medication, as it can increase the risk of side effects.
• Driving and Operating Machinery: Endacof AC may cause drowsiness, dizziness, or blurred vision. Avoid driving, operating heavy machinery, or engaging in activities requiring mental alertness until you know how this medication affects you.
• Avoiding Overdose: Take Endacof AC exactly as prescribed by your healthcare provider. Do not exceed the recommended dosage or use it for longer than prescribed, as misuse or overdose can lead to serious health consequences, including respiratory depression, coma, or death.

Always follow your healthcare provider’s instructions and recommendations when using Endacof AC to minimize risks and ensure safe and effective use. If you have any concerns or experience adverse effects while taking this medication, contact your healthcare provider promptly.

What special dietary instructions should I follow?

There are no specific dietary instructions for Endacof AC. However, it’s generally advisable to stay hydrated and maintain a balanced diet while taking any medication.

What should I do if I forget a dose?

If you forget a dose of Endacof AC, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Endacof AC, containing Brompheniramine and Codeine, may cause various side effects, although not everyone experiences them. Common side effects of this medication may include:

• Drowsiness or sedation: Brompheniramine and codeine can both cause drowsiness, which may impair your ability to perform tasks that require alertness, such as driving or operating machinery.
• Dizziness: Feeling lightheaded or dizzy is a common side effect of Endacof AC.
• Dry mouth: Brompheniramine may cause dryness in the mouth, which can lead to discomfort.
• Constipation: Codeine, being an opioid, can slow down bowel movements, leading to constipation.
• Nausea or vomiting: Some individuals may experience nausea or vomiting as a side effect of Endacof AC.
• Blurred vision: Vision may become blurred temporarily while taking this medication.
• Urinary retention: In some cases, codeine may cause difficulty urinating or urinary retention.
• Cognitive impairment: Endacof AC may affect cognitive function, causing confusion or difficulty concentrating.
• Respiratory depression: Codeine is an opioid and can suppress the respiratory system, especially at higher doses or in sensitive individuals. This can lead to shallow breathing or respiratory distress.
• Allergic reactions: Rarely, individuals may experience allergic reactions to components of Endacof AC, which can manifest as rash, itching, swelling, or difficulty breathing.

It’s essential to be aware of these potential side effects and to seek medical attention if you experience severe or persistent symptoms while taking Endacof AC. Additionally, if you have any concerns about side effects, discuss them with your healthcare provider. They can provide guidance and may adjust your medication regimen if necessary.

What should I know about storage and disposal of this medication?

Storage and Disposal:

• Storage: Store Endacof AC at room temperature away from moisture and heat. Keep it out of reach of children and pets.
• Disposal: Dispose of unused or expired Endacof AC safely by following local guidelines or drug take-back programs. Do not flush medications down the toilet or pour them into a drain unless instructed to do so.

In case of emergency/overdose

• Seek Medical Help: If you suspect an overdose of Endacof AC, seek immediate medical attention or contact a poison control center right away. Symptoms of overdose may include extreme drowsiness, shallow breathing, confusion, fainting, or coma.
• Do Not Delay: Do not delay seeking medical assistance if you suspect an overdose, as it can be life-threatening.

What other information should I know?

• Avoid Alcohol: Avoid consuming alcohol while taking Endacof AC, as it can increase the risk of side effects such as drowsiness, dizziness, or respiratory depression.
• Medical Alert: Inform healthcare providers about your use of Endacof AC, especially before undergoing surgery or medical procedures, as it may interact with certain anesthetics or medications.
• Regular Monitoring: Your healthcare provider may need to monitor your response to Endacof AC regularly, especially if you are using it for an extended period or have underlying medical conditions.
• Follow Directions: Take Endacof AC exactly as prescribed by your healthcare provider. Do not exceed the recommended dosage or use it for longer than prescribed.
• Avoid Driving: Endacof AC may cause drowsiness, dizziness, or blurred vision. Avoid driving, operating heavy machinery, or engaging in activities requiring mental alertness until you know how this medication affects you.
• Allergic Reactions: If you experience signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing, seek medical attention immediately.
• Consult Healthcare Provider: If you have any questions or concerns about Endacof AC, its side effects, or its usage, consult your healthcare provider for guidance.

By following these guidelines and being aware of important information about Endacof AC, you can use the medication safely and effectively.