Why is this medication prescribed?

Didronel (etidronate) is a medication primarily prescribed to treat Paget’s disease of bone, a condition where bones become enlarged and weakened. It works by slowing down the breakdown of bone tissue, helping to reduce bone pain and deformity associated with Paget’s disease.

How should this medicine be used?

Didronel is typically taken orally, usually as tablets, and the dosage and duration of treatment depend on the severity of the condition and the individual’s response to the medication. It’s important to follow the dosage instructions provided by your healthcare provider. Generally, it’s recommended to take Didronel on an empty stomach, at least two hours before or after eating, and to avoid lying down for at least 30 minutes after taking it to prevent irritation of the esophagus.

It’s crucial to inform your healthcare provider about any other medications you are taking, as well as any medical conditions you have, before starting Didronel, as it may interact with certain medications or exacerbate certain conditions. Additionally, regular monitoring and follow-up with your healthcare provider are essential to assess the effectiveness of the treatment and to watch for any potential side effects.

Other uses for this medicine

While Didronel (etidronate) is primarily prescribed for Paget’s disease of bone, it may also be used in certain cases for the treatment of heterotopic ossification (abnormal bone formation) following hip replacement surgery and for the prevention and treatment of osteoporosis in postmenopausal women. However, its efficacy for these conditions may vary, and its use should be determined by a healthcare professional based on individual circumstances.

What special precautions should I follow?

When taking Didronel, there are several special precautions to keep in mind:

• Kidney Function: Didronel is excreted through the kidneys, so individuals with impaired kidney function should use it cautiously or under medical supervision. Dosing adjustments may be necessary in these cases.
• Dental Health: Didronel has been associated with a rare condition called osteonecrosis of the jaw (ONJ), which involves the death of jawbone tissue. To minimize the risk of ONJ, maintain good oral hygiene and undergo regular dental check-ups before and during treatment with Didronel. Inform your dentist that you are taking this medication.
• Gastrointestinal Effects: Didronel can irritate the gastrointestinal tract, potentially leading to ulcers or irritation of the esophagus. To reduce the risk of these effects, take Didronel with a full glass of water and remain upright for at least 30 minutes after taking it. Avoid lying down for at least 30 minutes to help prevent irritation.
• Drug Interactions: Didronel may interact with other medications, including certain antibiotics, antacids, and calcium supplements. Inform your healthcare provider about all medications you are taking to avoid potential interactions.
• Calcium and Vitamin D Supplementation: Your healthcare provider may recommend calcium and vitamin D supplementation while taking Didronel, especially if you are being treated for osteoporosis. Follow their recommendations regarding supplementation.
• Pregnancy and Breastfeeding: Didronel should be used during pregnancy or breastfeeding only if the potential benefits outweigh the risks. Discuss the risks and benefits with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.

Always follow your healthcare provider’s instructions and guidance when taking Didronel, and report any unusual symptoms or side effects promptly.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Didronel. However, to maximize its effectiveness, it’s generally recommended to maintain a balanced diet rich in calcium and vitamin D, as these nutrients are essential for bone health.

What should I do if I forget a dose?

If you miss a dose of Didronel, take it as soon as you remember, unless it’s almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you’re unsure about what to do, consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

When taking Didronel, there are several special precautions to keep in mind:

• Kidney Function: Didronel is excreted through the kidneys, so individuals with impaired kidney function should use it cautiously or under medical supervision. Dosing adjustments may be necessary in these cases.
• Dental Health: Didronel has been associated with a rare condition called osteonecrosis of the jaw (ONJ), which involves the death of jawbone tissue. To minimize the risk of ONJ, maintain good oral hygiene and undergo regular dental check-ups before and during treatment with Didronel. Inform your dentist that you are taking this medication.
• Gastrointestinal Effects: Didronel can irritate the gastrointestinal tract, potentially leading to ulcers or irritation of the esophagus. To reduce the risk of these effects, take Didronel with a full glass of water and remain upright for at least 30 minutes after taking it. Avoid lying down for at least 30 minutes to help prevent irritation.
• Drug Interactions: Didronel may interact with other medications, including certain antibiotics, antacids, and calcium supplements. Inform your healthcare provider about all medications you are taking to avoid potential interactions.
• Calcium and Vitamin D Supplementation: Your healthcare provider may recommend calcium and vitamin D supplementation while taking Didronel, especially if you are being treated for osteoporosis. Follow their recommendations regarding supplementation.
• Pregnancy and Breastfeeding: Didronel should be used during pregnancy or breastfeeding only if the potential benefits outweigh the risks. Discuss the risks and benefits with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.

Always follow your healthcare provider’s instructions and guidance when taking Didronel, and report any unusual symptoms or side effects promptly.

What should I know about storage and disposal of this medication?

Here’s a detailed overview:

• Storage: Store Didronel (etidronate) tablets at room temperature, away from moisture and heat. Keep the medication in its original container, tightly closed, and out of reach of children and pets. Avoid storing it in the bathroom or other areas with high humidity.
• Disposal: Properly dispose of any unused or expired Didronel tablets. Do not flush them down the toilet or pour them down the drain unless instructed to do so. Instead, consult your pharmacist or local waste disposal company for guidance on how to safely dispose of medications.

In case of emergency/overdose

In the case of an emergency or overdose, such as severe symptoms or suspected overdose of Didronel, seek immediate medical attention. Contact your local poison control center or go to the nearest emergency room. Be prepared to provide information about the medication, dosage, and any symptoms experienced.

What other information should I know?

• Inform all healthcare providers involved in your care, including dentists, that you are taking Didronel. This medication may interact with other drugs or affect certain medical procedures.
• Attend all scheduled appointments with your healthcare provider for monitoring and follow-up during treatment with Didronel.
• Be cautious when engaging in activities that require alertness, as Didronel may cause dizziness or lightheadedness.
• Do not share Didronel with others, even if they have similar symptoms or conditions, as it may not be appropriate for them.
• Follow your healthcare provider’s recommendations regarding calcium and vitamin D supplementation, dietary considerations, and lifestyle modifications to support bone health.
• If you have any questions or concerns about Didronel or its use, consult your healthcare provider or pharmacist for guidance and clarification.

By adhering to these guidelines and staying informed about Didronel, you can ensure the safe and effective use of this medication.