Why is this medication prescribed?

Deucravacitinib is a medication used to treat moderate to severe plaque psoriasis in adults who are candidates for systemic therapy. It’s a Janus kinase (JAK) inhibitor, which works by blocking certain enzymes in the body that are involved in inflammation.

It’s typically prescribed when other systemic therapies or phototherapies have been ineffective or are not suitable for the individual. Deucravacitinib helps to reduce the symptoms of plaque psoriasis, including redness, scaling, and thickness of the skin.

How should this medicine be used?

As for how it should be used, Deucravacitinib is usually taken orally in the form of tablets. The dosage and frequency will depend on the individual’s medical condition and response to treatment. It’s important to follow the instructions provided by your healthcare provider carefully. Typically, it’s taken once daily with or without food.

However, it’s essential to consult with a healthcare professional for personalized guidance on how to use Deucravacitinib properly, as they can provide specific dosing instructions tailored to your needs and medical history. Additionally, they can monitor your progress and adjust the dosage if necessary to ensure the best possible outcome.

Other uses for this medicine

Deucravacitinib is primarily prescribed for the treatment of moderate to severe plaque psoriasis. However, its effectiveness in other conditions is still being researched. It’s important to note that using Deucravacitinib for conditions other than plaque psoriasis should only be done under the guidance and supervision of a healthcare professional.

What special precautions should I follow?

As for special precautions, there are several important points to consider when using Deucravacitinib:

• Medical History: Before starting Deucravacitinib, inform your healthcare provider about any medical conditions you have, especially if you have a history of infections, liver problems, or any other significant health issues.
• Pregnancy and Breastfeeding: Deucravacitinib may harm an unborn baby, so it’s crucial to avoid its use during pregnancy unless absolutely necessary. Similarly, it’s not recommended to breastfeed while taking Deucravacitinib, as it may pass into breast milk and harm the nursing infant.
• Infections: Deucravacitinib can increase the risk of infections, including serious and sometimes fatal infections. Before starting treatment, your healthcare provider may perform tests to check for any underlying infections. Inform your doctor if you develop signs of infection while taking Deucravacitinib, such as fever, chills, cough, or flu-like symptoms.
• Vaccinations: It’s generally recommended to be up to date with all vaccinations before starting Deucravacitinib, as it may interfere with the body’s ability to fight infections. However, live vaccines should be avoided during treatment with Deucravacitinib.
• Liver Function: Deucravacitinib may affect liver function, so regular monitoring of liver enzymes may be necessary during treatment. Inform your doctor of any signs of liver problems, such as yellowing of the skin or eyes, abdominal pain, or dark urine.
• Drug Interactions: Inform your healthcare provider about all the medications you are taking, including prescription, over-the-counter, and herbal supplements, as Deucravacitinib may interact with other drugs, potentially leading to adverse effects or reduced effectiveness.
• Side Effects: Be aware of potential side effects of Deucravacitinib, including but not limited to infections, increased cholesterol levels, and liver function abnormalities. Contact your healthcare provider if you experience any unusual symptoms while taking Deucravacitinib.

Always follow your healthcare provider’s instructions and guidance regarding the use of Deucravacitinib, and don’t hesitate to ask any questions or express any concerns you may have about the medication.

What special dietary instructions should I follow?

As for special dietary instructions, there are currently no specific dietary restrictions associated with Deucravacitinib. However, maintaining a healthy and balanced diet is generally recommended for overall well-being.

What should I do if I forget a dose?

If you forget to take a dose of Deucravacitinib, take it as soon as you remember, unless it is close to the time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you have any concerns or questions about missed doses, consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Deucravacitinib, like any medication, can cause side effects, although not everyone will experience them. Common side effects may include:

• Infections: Deucravacitinib can increase the risk of infections, including upper respiratory tract infections and urinary tract infections.
• Liver Function Abnormalities: Some people may experience changes in liver function tests while taking Deucravacitinib.
• Increased Cholesterol Levels: Deucravacitinib may lead to elevated levels of cholesterol and other lipids in the blood.
• Headache: Headaches are a commonly reported side effect of Deucravacitinib.
• Diarrhea: Gastrointestinal symptoms like diarrhea may occur in some individuals.
• Nausea: Feeling nauseous or experiencing vomiting can also happen with Deucravacitinib use.
• Upper Respiratory Tract Infections: Symptoms such as a sore throat, cough, or nasal congestion may occur.
• Elevated Creatine Phosphokinase (CPK) Levels: Deucravacitinib may cause increases in CPK levels, which may indicate muscle damage.
• Skin Reactions: Some individuals may experience skin reactions such as rash or itching.
• Headaches: Headaches are a commonly reported side effect of Deucravacitinib.
• Serious Infections: While less common, Deucravacitinib can increase the risk of serious infections, including tuberculosis and opportunistic infections such as fungal or bacterial infections.

It’s essential to report any unusual or bothersome side effects to your healthcare provider. Additionally, if you experience symptoms of a severe allergic reaction, such as difficulty breathing, swelling of the face, lips, tongue, or throat, or severe rash, seek immediate medical attention.

This list does not encompass all possible side effects of Deucravacitinib. Always consult with your healthcare provider for personalized advice regarding potential side effects and how to manage them.

What should I know about storage and disposal of this medication?

When it comes to the storage and disposal of Deucravacitinib, here are some important points to consider:

• Storage: Store Deucravacitinib at room temperature away from light and moisture. Avoid storing it in the bathroom or other areas with high humidity. Keep the medication out of reach of children and pets.
• Disposal: Dispose of any unused or expired Deucravacitinib properly according to local regulations or guidelines. Do not flush it down the toilet or pour it down the drain unless instructed to do so. Check with your pharmacist or local waste disposal authority for the appropriate disposal method.

In case of emergency/overdose

• Seek Medical Help: If you or someone else has taken too much Deucravacitinib or is experiencing severe symptoms, such as difficulty breathing, loss of consciousness, or seizures, call emergency services immediately or go to the nearest emergency room.
• Contact Poison Control: You can also contact your local poison control center for guidance on what to do in case of overdose. They can provide assistance and advice on managing the situation.
• Do Not Drive: If you’re experiencing severe symptoms or have taken an overdose of Deucravacitinib, do not attempt to drive yourself to the hospital. Seek assistance from someone else or call for an ambulance.

What other information should I know?

• Regular Monitoring: Your healthcare provider may conduct regular monitoring, including blood tests, to check for any potential side effects or complications while you’re taking Deucravacitinib.
• Follow-up Appointments: Attend all scheduled follow-up appointments with your healthcare provider to assess your response to treatment and make any necessary adjustments to your medication regimen.
• Patient Education: Make sure you understand how to take Deucravacitinib correctly, including dosing instructions, potential side effects, and what to do if you miss a dose or experience any adverse reactions.
• Drug Interactions: Inform your healthcare provider about all medications, supplements, and herbal products you are taking, as they may interact with Deucravacitinib and affect its effectiveness or increase the risk of side effects.

By being aware of these guidelines and following your healthcare provider’s instructions, you can safely and effectively use Deucravacitinib for the treatment of plaque psoriasis.