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Cosopt (Generic Dorzolamide and Timolol Ophthalmic)

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Why is this medication prescribed?

Eye diseases like glaucoma and ocular hypertension, where an increase in pressure can cause a gradual loss of vision, are treated with a combination of dorzolamide and timolol. Patients whose ocular condition has not improved after taking another medicine are prescribed dorzolamide and timolol. The drug dorzolamide belongs to the group of drugs known as topical carbonic anhydrase inhibitors. Timolol belongs to a group of drugs known as topical beta blockers. By reducing the amount of natural fluids produced in the eye, dorzolamide and timolol lower ocular pressure.

How should this medicine be used?

Dorzolamide and timolol are combined to make a solution (liquid) that is injected into the eye. Usually, it is injected into the afflicted eye(s) twice daily. Use dorzolamide and timolol at roughly the same times every day to help you remember to take them. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Dorzolamide and timolol must be used exactly as prescribed. Use it only as directed by your doctor, neither more nor less often.

Glaucoma and ocular hypertension are controlled but not cured by the combination of dorzolamide and timolol. Even if you feel good, keep taking the medications dorzolamide and timolol. Without consulting your doctor, never discontinue taking timolol with dorzolamide.

Follow these steps to administer the eye drops:

  • Use soap and water to thoroughly wash your hands.
  • Make sure the dropper tip is not broken or chipped by inspecting it.
  • Eye drops and droppers must be kept clean; avoid contacting the dropper tip to your eye or anything else.
  • Pull your lower eyelid down to create a pocket with your index finger while cocking your head back.
  • Using your other hand, place the dropper as near to your eye as you can without touching it, tip down.
  • Place the hand’s remaining fingers to your face.
  • Squeeze the dropper gently while looking up so that a single drop falls into the lower eyelid’s pocket. Your index finger should be taken off the lower eyelid.
  • Tip your head down so that you are looking at the floor while closing your eyes for two to three minutes. Avoid blinking or squeezing your eyelids.
  • Give the tear duct a slight squeeze with your finger.
  • Use a tissue to remove any extra liquid from your face.
  • Wait at least 5 minutes before administering the subsequent drop if you need to use more than one in the same eye.
  • Reinstall and secure the dropper bottle’s cap. Never rinse or clean the dropper tip.
  • To get rid of any medication, wash your hands.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before using dorzolamide and timolol eye drops,

  • If you have an allergy to dorzolamide (Trusopt), timolol (Timoptic), sulfa medications, or any other medications, let your doctor and pharmacist know right once.
  • Inform your physician and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are taking. Incorporate any of the following: Calcium channel blockers such amlodipine (Norvasc), diltiazem, and beta blockers like atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), and propranolol (Inderal) (Cardizem, Dilacor, Tiazac, others), felodipine (Plendil), isradipine (DynaCirc), nicardipine (Adalat, Procardia), nimodipine (Nimotop), nisoldipine (Sular), and verapamil (Calan, Isoptin, Verelan); carbonic anhydrase inhibitors like acetazolamide (Diamox), dichlorphenamide (Danaride), and aspirin, choline magnesium trisalicylate, choline salicylate (Arthropan), diflunisal (Dolobid), magnesium salicylate (Doan’s, other salicylate painkillers), and salsalate are examples of salicylate analgesics (Argesic, Disalcid, Salgesic). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • If you also need to apply any topical eye medication, do so at least 10 minutes before or after applying the dorzolamide and timolol.
  • Inform your physician if you currently have or previously had kidney or liver disease, severe allergic reactions, myasthenia gravis, asthma, lung conditions such chronic bronchitis and emphysema, heart conditions, diabetes, and hyperthyroidism.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you get pregnant while taking timolol and dorzolamide.
  • Inform the surgeon or dentist that you are taking dorzolamide and timolol if you are having surgery, including dental surgery.
  • You should be aware that the benzalkonium chloride in the dorzolamide and timolol solution can be absorbed by soft contact lenses. Before using dorzolamide and timolol on contact lenses, take them out. After 15 minutes, replace them.
  • If you use dorzolamide with timolol at the same time as having an eye injury, illness, or surgery, ask your doctor if you should keep using the same eye drop bottle.
  • You should be aware that if you have allergies to certain substances, using dorzolamide and timolol may make your symptoms worse and that your allergies may not be responsive to the standard doses of injectable epinephrine.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What should I do if I forget a dose?

The missed dose should be administered as soon as you remember. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not provide a second dose.

What side effects can this medication cause?

Timolol with dorzolamide could have negative side effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Changing tastes (bitter, sour, or unusual taste)
  • Eyes hurting or burning
  • Scratchy eyes
  • Wet eyes
  • Tearing up
  • Dizziness

Some adverse effects may be severe. Make a quick call to your doctor if you encounter any of the following signs:

  • Fuzzy vision
  • Body rash
  • Edoema of the lower legs, ankles, feet, or hands
  • Breathing difficulty
  • Red eye
  • Swelling or redness of the eyelid
  • Muscular tremor

Timolol with dorzolamide may also have other adverse effects. If you experience any strange issues while taking this drug, call your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Keep it away from excessive heat and moisture at room temperature (not in the bathroom).

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medications website at http://goo.gl/c4Rm4p for additional information.

Although many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning. http://www.upandaway.org

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Overdose symptoms could include:

  • Dizziness
  • Headache
  • Breathing difficulty
  • Breathing or swallowing challenges
  • Chest ache
  • Confusion

What other information should I know?

Keep all of your doctor’s appointments.

Do not share your medication with anybody else. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Cosopt®
  • Cosopt® PF
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