Why is this medication prescribed?

Combivent Metered Dose Inhaler (MDI) is prescribed for the treatment of chronic obstructive pulmonary disease (COPD), which includes chronic bronchitis and emphysema. It is used to improve breathing by relaxing the muscles around the airways to make breathing easier.

How should this medicine be used?

Combivent Metered Dose Inhaler (MDI) is a medication used for treating chronic obstructive pulmonary disease (COPD) by helping to open the airways for easier breathing. Here’s how it should generally be used:

• Shake the Inhaler: Before using Combivent MDI, shake the inhaler well to ensure the medication is properly mixed.
• Prepare for Inhalation: Remove the cap from the mouthpiece. Check to make sure the mouthpiece is clean and free from any debris.
• Prime the Inhaler (if needed): If you are using the inhaler for the first time or if it has not been used for more than 3 days, it may need to be primed. This typically involves spraying a few test sprays into the air away from your face to ensure the inhaler is working correctly.
• Breathe Out: Breathe out fully to prepare for inhalation.
• Inhale the Medication: Hold the inhaler upright with the mouthpiece at the bottom. Place the mouthpiece between your lips and close your lips tightly around it. Start breathing in slowly and deeply through your mouth, and press down on the top of the inhaler to release one puff of medication. Continue breathing in slowly and deeply for 3-5 seconds to ensure the medication reaches deep into your lungs.
• Hold Breath and Breathe Out: Hold your breath for 10 seconds if possible to allow the medication to settle in your airways. Breathe out slowly and gently away from the inhaler.
• Wait (if necessary): If your healthcare provider has instructed you to take more than one puff, wait 15-30 seconds before taking the next puff. Shake the inhaler again before repeating the steps.
• Replace the Cap: After use, replace the cap on the mouthpiece to keep it clean.
• Rinse Mouth (if needed): If the medication leaves a bitter taste in your mouth, rinse your mouth with water after using the inhaler to help reduce this taste.

Always follow the specific instructions provided by your healthcare provider or pharmacist for using Combivent MDI, as they may vary depending on your individual condition and needs. It’s important to use this medication exactly as prescribed to get the most benefit from it and to minimize the risk of side effects. If you have any questions or concerns about how to use Combivent MDI, don’t hesitate to ask your healthcare provider or pharmacist for clarification.

Other uses for this medicine

• Asthma: In some cases, Combivent MDI may be prescribed for asthma, particularly for patients who require both a bronchodilator (albuterol) and an anticholinergic (ipratropium bromide).
• Other Respiratory Conditions: Your doctor may prescribe Combivent MDI for other respiratory conditions where bronchodilation is needed, based on their clinical judgment.

What special precautions should I follow?

When using Combivent MDI, it’s important to be aware of the following precautions:

• Allergies: Inform your doctor if you have any allergies to ipratropium, albuterol, or any other medications. Also, mention any allergies to foods, dyes, preservatives, or animals.
• Medical Conditions: Tell your doctor about any medical conditions you have, especially heart conditions (e.g., heart disease, irregular heartbeat), high blood pressure, thyroid disorders, diabetes, seizures, or urinary problems (e.g., enlarged prostate).
• Pregnancy and Breastfeeding: If you are pregnant or breastfeeding, discuss the risks and benefits of using Combivent MDI with your doctor. Generally, medications like Combivent should be used during pregnancy or breastfeeding only if clearly needed and prescribed by a healthcare provider.
• Other Medications: Inform your doctor about all the medications you are taking, including prescription drugs, over-the-counter medicines, vitamins, and herbal supplements. Some medications may interact with Combivent MDI, potentially affecting how it works or causing side effects.
• Use as Directed: Follow the prescribed dosage instructions carefully. Using more than the recommended dose or using it more frequently than prescribed can increase the risk of side effects.
• Side Effects: Be aware of possible side effects, such as dry mouth, throat irritation, dizziness, blurred vision, or rapid heart rate. Report any unusual symptoms to your doctor promptly.
• Handling: Properly store Combivent MDI at room temperature, away from moisture and heat. Do not puncture or incinerate the canister, even if it is empty.

Always consult your healthcare provider or pharmacist if you have any questions or concerns about using Combivent MDI, especially if you experience any unexpected symptoms or changes in your condition.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with the use of Combivent MDI. However, it’s generally recommended to maintain a healthy diet and stay well-hydrated, especially if you have a chronic respiratory condition like COPD. If you have any concerns about diet or nutrition while using Combivent MDI, discuss them with your healthcare provider or a registered dietitian.

What should I do if I forget a dose?

If you forget to take a dose of Combivent MDI, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Combivent Metered Dose Inhaler (MDI), like any medication, can cause side effects, although not everyone using it will experience them. Common side effects of Combivent MDI include:

• Dry Mouth: This is one of the most common side effects, caused by the anticholinergic component (ipratropium bromide) of Combivent.
• Throat Irritation: Some people may experience irritation or dryness in the throat after using the inhaler.
• Tremors: Mild trembling or shaking of the hands or fingers may occur due to the beta-adrenergic component (albuterol) in Combivent.
• Nervousness or Anxiety: Albuterol can sometimes cause feelings of nervousness or anxiety.
• Headache: Mild to moderate headaches may occur as a side effect.
• Dizziness: Some individuals may feel dizzy or lightheaded after using Combivent MDI.
• Blurred Vision: Temporary blurred vision or difficulty focusing may occur, although this is less common.
• Fast Heart Rate (Tachycardia): Albuterol can cause an increase in heart rate, which may be noticeable, especially if you are sensitive to stimulant medications.
• Palpitations: Some people may experience awareness of their heart beating (palpitations) after using Combivent.
• Cough: A mild cough may occur, particularly at the beginning of treatment.
• Gastrointestinal Symptoms: These can include nausea, upset stomach, or diarrhea, though they are less common.

Serious Side Effects: While less common, serious side effects may occur with Combivent MDI. If you experience any of the following, seek medical attention immediately:

• Allergic Reactions: Symptoms may include rash, itching, swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.
• Worsening of Breathing Problems: If your breathing problems worsen shortly after using Combivent MDI (paradoxical bronchospasm), discontinue use and seek medical help.
• Chest Pain: Chest pain or discomfort could indicate a serious heart condition.
• Irregular Heartbeat: If you experience a rapid or irregular heartbeat that is persistent or severe.
• High Blood Pressure: In some cases, Combivent MDI may cause an increase in blood pressure.
• Difficulty Urinating: This can be a sign of urinary retention, particularly in men with prostate problems.
• Severe Headache: If you develop a severe headache after using Combivent MDI.

It’s essential to discuss any concerns or unusual symptoms with your healthcare provider. They can help determine whether any side effects you experience are related to Combivent MDI and provide guidance on managing them effectively.

What should I know about storage and disposal of this medication?

Storage and Disposal of Combivent Metered Dose Inhaler:

• Storage:
  • Store Combivent MDI at room temperature between 68-77°F (20-25°C).
  • Avoid exposure to excessive heat or direct sunlight.
  • Do not puncture or incinerate the canister, even if it is empty.
• Handling:
  • Keep the inhaler away from moisture or humidity.
  • Keep it out of reach of children and pets.
  • Store the inhaler with the mouthpiece cap securely in place to prevent contamination.
• Disposal:
  • Dispose of the Combivent MDI canister properly when it is empty or no longer needed.
  • Do not throw the canister into a fire or incinerator.
  • Check with your pharmacist or local waste disposal company for instructions on how to safely dispose of expired or unused medication.

In case of emergency/overdose

• Symptoms of Overdose: Symptoms of an overdose may include chest pain, fast or irregular heartbeats, tremor, nervousness, headache, dizziness, dry mouth, difficulty sleeping, nausea, or seizures.
• Emergency Actions:
  • If you suspect an overdose or experience severe symptoms after using Combivent MDI, seek immediate medical attention.
  • Call emergency services (911 in the US) or a poison control center immediately.
  • Do not try to treat an overdose on your own without medical guidance.

What other information should I know?

• Regular Follow-Up: Attend regular appointments with your healthcare provider to monitor your condition and response to Combivent MDI.
• Usage Consistency: Use Combivent MDI exactly as prescribed. Do not increase or decrease the dosage without consulting your doctor.
• Avoiding Contamination: Keep the mouthpiece clean and free of debris to prevent contamination and ensure proper medication delivery.
• Monitoring: Be aware of how your body responds to Combivent MDI, and report any new or worsening symptoms to your doctor promptly.
• Refills: Ensure you have an adequate supply of Combivent MDI. Check with your pharmacist about refilling your prescription before you run out.

Always follow the instructions provided by your healthcare provider and the medication guide that comes with Combivent MDI. If you have any questions or concerns about its use, storage, or disposal, consult your healthcare provider or pharmacist for clarification and guidance specific to your situation.