When taken with some drugs, clorazepate may raise the risk of serious or life-threatening breathing issues, sedation, or coma. Inform your doctor if you are currently taking or intend to start taking any opiate medications, including codeine (in Triacin-C, Tuzistra XR) or hydrocodone (in Anexsia, Norco, or Zyfrel) for coughing or codeine (in Fiorinal) for pain. Other opiate medications include fentanyl (Actiq, Duragesic, Subsys), hydromorphone (Dilaudid, Exalgo (Conzip, Ultram, in Ultracet). Your doctor will closely monitor you and may need to adjust the dosage of your drugs. If you use clorazepate along with any of these drugs and experience any of the following symptoms, call your doctor right once or go to the emergency room right away: unusual dizziness, lightheadedness, extreme drowsiness, slowed or trouble breathing, or unresponsiveness. Make sure your carer or family members are aware of any symptoms that might be dangerous so they can contact a doctor or emergency services on your behalf if you are unable to get help on your own.

The drug clorazepate has the potential to cause addiction. Never exceed the recommended dosage, frequency, or duration. Always follow your doctor’s instructions. Inform your doctor if you use or have ever used illicit drugs, consumed excessive amounts of alcohol, or have ever misused any prescription drugs. Don’t consume alcohol or use illicit substances while receiving treatment. You run a higher chance of developing these severe, sometimes fatal side effects if you use illicit drugs or drink while taking clorazepate. Additionally let your doctor know if you suffer from depression or any other mental disease now or in the past.

If you take clorazepate for several days to weeks, especially, you run the risk of developing physical dependence, which manifests as unpleasant physical symptoms if a medication is abruptly withdrawn or taken in reduced quantities. Without first seeing your doctor, never stop taking this drug or reduce your dose. Sudden discontinuation of clorazepate can exacerbate your disease and result in withdrawal symptoms that could last anywhere from a few weeks to over a year. Your doctor will probably progressively lower your clorazepate dosage. If you encounter any of the following symptoms, call your doctor or seek emergency medical attention: Unusual movements, ringing in the ears, anxiety, memory issues, difficulty concentrating, sleep issues, seizures, shaking, muscle twitching, changes in mental health, depression, burning or prickling sensations in the hands, arms, legs, or feet, thoughts of harming or killing yourself or others, excessive excitement, or losing touch with reality are some of the symptoms that can accompany these conditions.

The anxiety-relieving drug clorazepate is utilised. Certain forms of seizures are also treated with clorazepate in combination with other drugs. It is also used to treat unpleasant side effects that may appear in persons who have quit drinking alcohol after consuming significant amounts over an extended period of time. The drug clorazepate belongs to the group of drugs known as benzodiazepines. It reduces the brain’s aberrant electrical activity in order to work.

To be taken orally, clorazepate is available as a tablet. Typically, it is taken once to three times each day. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Use clorazepate as prescribed by your doctor.

Your doctor will likely start you on a low dose of clorazepate and gradually raise it if you are taking it to treat anxiety or seizures. Your doctor will likely start you on a high dose of clorazepate to treat alcohol withdrawal, then gradually lower the dose when your symptoms are under control.

Although clorazepate may aid in seizure control and anxiety reduction, these disorders cannot be cured. Clorazepate should be taken even if you feel fine.

Other prescriptions for this drug are possible. For more information, consult your physician or pharmacist.

Before taking clorazepate,

• Inform your doctor and pharmacist if you have any allergies to clorazepate, other benzodiazepines such alprazolam (Xanax), chlordiazepoxide (Librium, in Librax), clonazepam (Klonopin), diazepam (Diastat, Valium), estazolam, flurazepam, lorazepam (Ativan), oxazepam, temazepam Get a list of the components from your pharmacist.
• Inform your doctor and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products that you are now taking or intend to use. Incorporate any of the following: levodopa (in Ritary, Sinemet, and Stalevo), chlorpromazine, cimetidine (Tagamet), disulfiram (Antabuse), and barbiturates such phenobarbital and secobarbital (Seconal); or monoamine oxidase inhibitors such tranylcypromine (Parnate), isocarboxazid (Marplan), linezolid (Zyvox), phenelzine (Nardil), selegiline (Eldepryl, Emsam), and phenelzine; drugs for depression, nausea, seizures, and mental disease; sedatives; sleeping pills; and tranquillizers. Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
• If you have glaucoma or have ever had it, let your doctor know. Your physician might advise against taking clorazepate.
• If you have or have previously had liver or kidney disease, let your doctor know.
• Inform your physician if you are nursing a baby, intend to get pregnant, or are already pregnant. Call your doctor if you get pregnant while taking clorazepate.
• If you are 65 years of age or older, discuss the advantages and disadvantages of taking clorazepate with your doctor. Clorazepate is typically not recommended for usage in older adults since it is less reliable and less efficient than alternative drugs that can be used to treat the same disease.
• You should let your doctor or dentist know if you are taking clorazepate if you are having surgery, including dental surgery.
• You should be aware that this medicine may cause you to feel sleepy. Prior to understanding how this drug affects you, avoid using machinery or driving a car.
• You should be aware that while taking clorazepate for the treatment of epilepsy, mental illness, or other illnesses, your mental health may alter in unexpected ways and you may become suicidal (thinking about injuring or killing oneself, preparing to do so, or trying to do so). In clinical studies, a small percentage of patients receiving anticonvulsants like clorazepate to treat various conditions—about 1 in 500 adults and children aged 5 and older—became suicidal while receiving medication. Some of these individuals started exhibiting suicidal thoughts and actions as little as one week after beginning the medicine. If you take an anticonvulsant drug like clorazepate, there is a chance that your mental state may change, but there is also a chance that your condition will not be addressed and that your mental state will alter. Whether the hazards of using an anticonvulsant drug outweigh the dangers of not using it will be decided by you and your doctor. Any of the following symptoms should prompt you, your family, or your carer to call your doctor immediately away: agitation or restlessness; panic episodes; acting on risky impulses, having trouble getting or staying asleep, or displaying new or increasing signs of irritation, anxiety, or depression; Mania (a frenetic, unusually exuberant mood), talking or thinking about wanting to harm yourself or end your life, withdrawing from friends and family, being preoccupied with death and dying, throwing up valued items, or any other unexpected changes in behaviour or attitude are all examples of mania. Make sure your family or carer is aware of any symptoms that could be significant so they can contact the doctor on your behalf if you are unable to call for help.

Keep eating normally unless your doctor instructs you otherwise.

The missed dose should be taken as soon as you remember. If your next dose is approaching, skip the missed one and carry on with your regular dosing regimen.

Side effects are possible with clorazepate. If any of these symptoms are severe or do not go away, let your doctor know right once:

• Drowsiness
• Dizziness
• Tiredness
• Headache
• Nervousness
• Confusion
• Mouth ache

Some adverse effects may be severe. Call your doctor right away or seek emergency medical attention if any of the following symptoms occur, in addition to those in the IMPORTANT WARNING section:

• Double or blurry vision
• Body part shaking that is uncontrollable
• Muddled speech
• Trouble maintaining balance
• Rash

Further negative effects of clorazepate are possible. If you experience any strange issues while taking clorazepate, contact your doctor right once.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

Keep this medication tightly closed in the original container and out of the reach of children. Keep it away from excessive heat and moisture at room temperature (not in the bathroom).

Although many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning. http://www.upandaway.org

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medications website at http://goo.gl/c4Rm4p for additional information.

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Keep all of your appointments with your physician and the lab. To monitor your body’s reaction to clorazepate, your doctor will request specific lab tests.

No one else should take your medication. The drug clorazepate is under strict monitoring. Only a limited amount of refills are permitted for prescriptions; if you have any doubts, speak with your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.