WARNING

Cimduo is a combination medication used to treat HIV-1 infection in adults. Like any medication, it carries certain risks and potential side effects. Here are some of the risks associated with taking Cimduo:

• Allergic reactions: Some people may experience allergic reactions to Cimduo, which can range from mild to severe. Symptoms may include rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.
• Liver problems: Cimduo can cause liver problems, including liver enlargement (hepatomegaly) and liver damage (hepatotoxicity). Your healthcare provider will monitor your liver function through blood tests.
• Lactic acidosis: This is a rare but serious condition that can occur due to Cimduo use. It involves the buildup of lactic acid in the body, which can be fatal if not treated promptly.
• Immune reconstitution syndrome: When starting HIV treatment, including Cimduo, some people may develop an inflammatory response to latent or residual opportunistic infections. This can cause symptoms that were not present before starting treatment or may worsen existing symptoms.
• Bone problems: Some HIV medications, including those in Cimduo, may contribute to bone loss or osteoporosis, especially with long-term use.
• Other common side effects: These can include nausea, headache, diarrhea, tiredness, and trouble sleeping. It’s essential to report any persistent or severe side effects to your healthcare provider.

Always follow your healthcare provider’s instructions carefully when taking Cimduo or any other medication for HIV. They can help monitor for potential side effects and adjust treatment as necessary to ensure your safety and effectiveness of the medication.

Why is this medication prescribed?

Cimduo is prescribed for the treatment of HIV-1 infection in adults. It is used in combination with other antiretroviral medications to help control HIV infection and reduce the amount of HIV in the body (viral load). By lowering the viral load, Cimduo helps to improve immune function and reduce the risk of HIV-related illnesses.

How should this medicine be used?

Cimduo comes in tablet form and is typically taken by mouth once daily with or without food. The dosage and specific combination of medications will depend on your individual HIV treatment regimen prescribed by your healthcare provider.

Here are some general guidelines for using Cimduo:

• Follow your doctor’s instructions: Take Cimduo exactly as prescribed. Do not alter your dosage or stop taking the medication without consulting your healthcare provider.
• Take at the same time each day: It is important to establish a routine and take Cimduo at the same time each day to maintain consistent levels of the medication in your body.
• Swallow whole: Do not crush, chew, or break the tablets. Swallow them whole with water.
• Food considerations: Cimduo can be taken with or without food. You can take it with a meal if you prefer, but it is not necessary to take it with food for it to be effective.
• Continue treatment: HIV treatment with Cimduo is usually long-term. It is important to continue taking the medication even if you feel well, as stopping could allow the virus to become resistant to treatment.
• Store properly: Keep Cimduo in its original container at room temperature, away from moisture and heat.
• Regular monitoring: Your healthcare provider will regularly monitor your HIV viral load, CD4 cell count, and overall health to ensure the medication is working effectively and to check for any potential side effects.

Always communicate openly with your healthcare provider about any concerns or questions you have regarding your treatment with Cimduo. They can provide personalized guidance based on your medical history and current health status.

Other uses for this medicine

Cimduo is specifically approved for the treatment of HIV-1 infection in adults and is not typically used for other medical conditions or purposes. Its primary role is to suppress the HIV virus and improve immune function in individuals diagnosed with HIV-1.

What special precautions should I follow?

When taking Cimduo, there are several special precautions to keep in mind:

• Pregnancy and breastfeeding: Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. HIV medications can affect pregnancy outcomes and the transmission of HIV to your baby. Your doctor will discuss the risks and benefits of continuing or starting Cimduo during pregnancy or breastfeeding.
• Liver function: Cimduo can cause liver problems, so it is important to have regular monitoring of your liver function. Your healthcare provider will perform blood tests to check your liver enzymes before starting treatment and periodically during treatment.
• Kidney function: Some HIV medications, including those in Cimduo, can affect kidney function. Your doctor may monitor your kidney function with blood tests while you are taking Cimduo.
• Drug interactions: Cimduo may interact with other medications, including over-the-counter drugs and supplements. Inform your healthcare provider about all medications you are currently taking to avoid potential interactions that could affect the effectiveness of Cimduo or other medications.
• Adherence to treatment: It is crucial to take Cimduo exactly as prescribed by your healthcare provider. Missing doses or not following the prescribed regimen can lead to viral resistance and treatment failure.
• Immune reconstitution syndrome: When starting HIV treatment, including Cimduo, some individuals may experience an inflammatory response to latent or residual opportunistic infections. This can cause symptoms that were not present before starting treatment or may worsen existing symptoms. Monitor any new symptoms and inform your healthcare provider promptly.
• Bone health: HIV medications, including those in Cimduo, may contribute to bone loss or osteoporosis over time. Discuss bone health monitoring and preventive measures with your healthcare provider.
• Allergic reactions: If you have had an allergic reaction to any components of Cimduo or similar medications in the past, inform your doctor. Allergic reactions can be serious and may require immediate medical attention.

Always follow your healthcare provider’s instructions and discuss any concerns you have about Cimduo or your HIV treatment regimen. They can provide personalized advice based on your medical history and current health status.

What special dietary instructions should I follow?

There are no specific dietary restrictions for Cimduo. You can take it with or without food. However, maintaining a healthy and balanced diet is important for overall health, especially when living with HIV. Your healthcare provider may recommend a nutritious diet to support your immune system and overall well-being.

What should I do if I forget a dose?

If you forget to take a dose of Cimduo, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Cimduo, like any medication, can cause side effects. Not everyone will experience these side effects, and their severity can vary. Here are some common side effects associated with Cimduo:

• Nausea: Feeling sick to your stomach, sometimes with vomiting.
• Headache: Mild to moderate headaches can occur.
• Diarrhea: Changes in bowel habits, including loose stools.
• Fatigue: Feeling tired or weak.
• Insomnia: Difficulty falling asleep or staying asleep.
• Dizziness: Feeling lightheaded or dizzy.
• Rash: Skin reactions such as a rash or itching.
• Abdominal pain: Discomfort or pain in the stomach area.
• Liver problems: Elevated liver enzymes or liver function abnormalities.
• Muscle pain: Aches or discomfort in muscles.
• Changes in fat distribution: Redistribution or accumulation of body fat, which can affect appearance.
• Immune reconstitution syndrome: Inflammatory response to latent or residual opportunistic infections when starting HIV treatment.
• Other less common side effects: These can include mood changes, kidney problems, pancreatitis, and changes in blood sugar levels.

It’s important to note that these are not all the possible side effects of Cimduo. Some individuals may experience more severe side effects or allergic reactions, which require immediate medical attention. If you experience any unusual symptoms while taking Cimduo, especially severe or persistent symptoms, notify your healthcare provider promptly.

Your doctor can help manage any side effects and adjust your treatment regimen if necessary to minimize discomfort and ensure the effectiveness of your HIV treatment.

What should I know about storage and disposal of this medication?

Storage and disposal of Cimduo:

• Storage: Store Cimduo tablets at room temperature between 68°F to 77°F (20°C to 25°C). Keep the medication in its original container, tightly closed, and away from moisture and heat.
• Disposal: Dispose of any unused or expired Cimduo tablets according to local regulations or guidelines. Do not flush them down the toilet or throw them in the trash. Your healthcare provider or pharmacist can provide guidance on the proper disposal method.

In case of emergency/overdose

In case of an overdose or emergency related to Cimduo, contact your local emergency services (such as 911) or go to the nearest emergency room immediately. Symptoms of an overdose may include severe dizziness, nausea, vomiting, and unusual weakness or fatigue. Be prepared to provide information about the medication you have taken and its dosage.

What other information should I know?

• Regular monitoring: Your healthcare provider will monitor your HIV viral load, CD4 cell count, and overall health regularly to assess the effectiveness of Cimduo and watch for any side effects or complications.
• Adherence to treatment: It is essential to take Cimduo exactly as prescribed by your healthcare provider. Missing doses or not following the prescribed regimen can lead to treatment failure and the development of drug-resistant HIV strains.
• Transmission of HIV: While Cimduo helps reduce HIV viral load, it does not cure HIV infection or prevent its transmission to others. Practice safe sex and use appropriate precautions to prevent transmitting HIV to others.
• Regular healthcare visits: Keep scheduled appointments with your healthcare provider for follow-up visits and monitoring. Discuss any concerns or questions you have about your treatment or overall health.
• Support services: Seek support from healthcare professionals, support groups, or counselors specializing in HIV care if you have emotional or psychological concerns related to your HIV diagnosis and treatment.
• Medication interactions: Inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking to avoid potential interactions with Cimduo.

By staying informed about storage, disposal, emergency procedures, and other essential information, you can effectively manage your treatment with Cimduo and maintain your health while living with HIV.