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Chloromycetin Injection (Generic Chloramphenicol Injection)

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WARNING

Some blood cell types may become less prevalent in the body as a result of receiving chloramphenicol injection. Those who experienced this drop in blood cells occasionally went on to acquire leukaemia (cancer that begins in the white blood cells). Whether you are receiving chloramphenicol treatment for a long time or a short time, you could still see this decrease in blood cells. Call your doctor right away if you have any of the following symptoms: Pale complexion, extreme exhaustion, shortness of breath, disorientation, rapid heartbeat, unusual bleeding or bruising, or symptoms of infection as chills, fever, coughing, and sore throat.

Throughout your therapy, your doctor will frequently request laboratory testing to see if your body’s blood cell count has reduced. You should be aware that these tests may not always pick up on alterations in the body that could result in a long-term drop in the amount of blood cells. It is preferable if you receive your chloramphenicol injection in a hospital setting where you may be carefully observed by your physician.

If another antibiotic is available to treat your infection, avoid using chloramphenicol injection. It must not be used to treat or prevent the spread of diseases, or to treat mild illnesses, colds, flu, or throat infections.

The dangers of receiving a chloramphenicol injection should be discussed with your doctor.

Why is this medication prescribed?

When other antibiotics are ineffective, chloramphenicol injection is used to treat some types of severe bacterial infections. The drug chloramphenicol injection belongs to the category of drugs known as antibiotics. It acts by preventing bacterial development.

Colds, the flu, or other viral diseases cannot be treated with antibiotics such as chloramphenicol injection. Antibiotic use that is not necessary raises the likelihood of developing a later infection that is resistant to antibiotic treatment.

How should this medicine be used?

A doctor or nurse must provide a liquid form of chloramphenicol injection into a patient’s vein while they are in the hospital. Usually, it is given every six hours. The type of infection being treated determines how long you will need to receive treatment. Your doctor can change you to another oral antibiotic after your condition becomes better to finish your therapy.

During the initial days of treatment with chloramphenicol injection, you should start to feel better. Inform your doctor if your symptoms do not get better or worsen.

Even if you feel better, continue using the chloramphenicol injection for whatever long your doctor instructs. Your illness could not be entirely treated if you stop using chloramphenicol injection too soon or skip doses, and the bacteria might develop an antibiotic resistance.

Other uses for this medicine

Chloramphenicol injection may be used to treat and prevent severe illnesses that are purposefully disseminated, such as plague, tularemia, and anthrax of the skin or mouth, in the event of biological warfare. The dangers of using this drug for your illness should be discussed with your doctor.

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before receiving chloramphenicol injection,

  • If you have any drug allergies, talk to your doctor and pharmacist about chloramphenicol injection.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter medications, vitamins, herbal items, nutritional supplements, and any drugs you are now taking or intend to take. Any of the following should be mentioned: Warfarin (Coumadin), aztreonam (Azactam), and other anticoagulants (sometimes known as “blood thinners”); cefoperazone (Cefobid), cefotaxime (Claforan), ceftazidime (Fortaz, Tazicef), and ceftriaxone (Rocephin) are examples of cephalosporin antibiotics. Folic acid; cyanocobalamin (vitamin B12); iron supplements, several oral diabetes treatments like chlorpropamide (Diabinese) and tolbutamide, phenobarbital, phenytoin (Dilantin, Phenytek), rifampin (Rimactane, Rifadin), and drugs that could lower the body’s level of blood cells are among the list of potential contraindications. A decrease in the number of blood cells may be caused by one or more of the medications you are taking, so check with your doctor or pharmacist about this. Your doctor might need to adjust your medication doses or keep a close eye out for any negative side effects. Chloramphenicol injection may also interact with other drugs, so be sure to let your doctor know about all the drugs you’re taking, even ones not on this list.
  • If you have ever received chloramphenicol injectable therapy, let your doctor know, especially if you had any negative side effects. Your physician could advise against using chloramphenicol injection.
  • If you have kidney or liver problems now or in the past, let your doctor know.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you conceive while having a chloramphenicol injection.
  • Inform the surgeon or dentist that you received a chloramphenicol injection if you are having surgery, including dental surgery.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What side effects can this medication cause?

The injection of chloramphenicol could have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Nausea
  • Vomiting
  • Diarrhea
  • Mouth or tongue sores
  • Headache
  • Depression
  • Confusion

Some adverse effects may be severe. Call your doctor right away if you have any of the following symptoms or any of the ones detailed in the IMPORTANT CAUTION section:

  • Hives
  • Rash
  • Itching
  • Edoema of the hands, feet, ankles, lower legs, cheeks, neck, tongue, lips, and eyes
  • Hoarseness
  • Breathing or swallowing challenges
  • Red or watery stools (up to 2 months after your treatment)
  • Stomach pain
  • Muscular weakness or pains
  • Sweating
  • Sensations of tingling, numbness, or pain in the arm or leg
  • Abrupt alterations in eyesight
  • Ache when moving the eyes

Gray syndrome is a disorder that can affect premature and newborn newborns who get chloramphenicol injection. Gray syndrome has also been reported in infants younger than 2 years old and in women who received a chloramphenicol injection during birth. After 3 to 4 days of treatment, symptoms, which typically include stomach bloating, vomiting, blue lips and skin from a lack of oxygen in the blood, low blood pressure, breathing difficulties, and even death, may appear. If treatment is discontinued as soon as any symptoms appear, the infant may fully recover and the symptoms may disappear. Discuss the dangers of using this drug to treat infants and young children or during childbirth with your doctor.

There may be further negative effects from chloramphenicol injection. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Any queries you may have regarding chloramphenicol injection should be directed to your doctor. Following the chloramphenicol injection, consult your doctor if you continue to experience infection-related symptoms.

You should keep a written record of every drug you take, including prescription and nonprescription (over-the-counter) medications, vitamins, minerals, and other dietary supplements. Every time you see a doctor or are admitted to the hospital, you should carry this list with you. Also, it is crucial to have this knowledge on hand in case of emergency.

Brand names

  • Chloromycetin® Injection
  • Mychel-S® Injection
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