Why is this medication prescribed?

Cevimeline is prescribed primarily to treat symptoms of dry mouth caused by Sjogren’s syndrome, which is an autoimmune disorder that affects the moisture-producing glands of the body, including those that produce saliva. Sjogren’s syndrome leads to dryness in the mouth and eyes, among other symptoms.

How should this medicine be used?

Cevimeline should be used as:

• Dosage: Cevimeline is typically taken orally in the form of a capsule.
• Frequency: The usual recommended dose is 30 mg three times daily (total of 90 mg per day).
• Administration: It should be taken with meals, as food can enhance its absorption and reduce potential side effects like nausea.
• Follow Doctor’s Instructions: Always follow the dosage instructions provided by your doctor or pharmacist. They will determine the appropriate dosage based on your condition and response to treatment.
• Duration: Continue taking Cevimeline for as long as prescribed by your doctor. Do not stop taking it without consulting your doctor, even if you start to feel better.
• Missed Dose: If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
• Side Effects: Be aware of potential side effects such as sweating, increased saliva production, blurred vision, nausea, and abdominal pain. If these side effects persist or worsen, inform your doctor promptly.
• Precautions: Inform your doctor about any other medications you are taking, as Cevimeline may interact with certain drugs. It’s important to discuss your medical history, especially if you have certain conditions like asthma, kidney disease, or other conditions that may affect how your body responds to Cevimeline.

Always consult your healthcare provider for personalized advice regarding the use of Cevimeline, as they can tailor the treatment to your specific needs and monitor you for any potential side effects or interactions.

Other uses for this medicine

Some studies and clinical experiences suggest potential benefits in treating dry mouth caused by medications, radiation therapy to the head and neck, and other conditions where saliva production is reduced.

What special precautions should I follow?

When using Cevimeline, it’s essential to follow these precautions to ensure safe and effective treatment:

• Allergies: Inform your doctor if you are allergic to Cevimeline or any other medications.
• Medical Conditions: Discuss your medical history with your doctor, especially if you have conditions such as asthma, chronic obstructive pulmonary disease (COPD), kidney disease, urinary tract obstruction, or other conditions that may affect your ability to tolerate Cevimeline.
• Pregnancy and Breastfeeding: Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. The use of Cevimeline during pregnancy should be considered only if the potential benefits outweigh the potential risks to the fetus.
• Driving and Operating Machinery: Cevimeline may cause blurred vision or dizziness in some individuals. If you experience these effects, avoid activities that require clear vision or alertness until you know how Cevimeline affects you.
• Interactions: Cevimeline can interact with other medications, including anticholinergic drugs, medications for Parkinson’s disease, and certain antidepressants. Inform your doctor about all medications, supplements, and herbal products you are taking to avoid potential interactions.
• Side Effects: Be aware of potential side effects such as increased sweating, increased saliva production, nausea, abdominal pain, headache, and dizziness. Report any persistent or severe side effects to your doctor promptly.
• Dosage: Take Cevimeline exactly as prescribed by your doctor. Do not change your dose or stop taking Cevimeline without consulting your doctor, even if you start to feel better.
• Monitoring: Your doctor may periodically monitor your response to Cevimeline and adjust your dosage as needed based on your condition and any side effects you may experience.

By following these precautions and guidelines, you can help ensure that Cevimeline is used safely and effectively for your specific condition. Always consult your healthcare provider for personalized advice regarding the use of Cevimeline and any other medications.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Cevimeline. However, it is generally recommended to take Cevimeline with meals to reduce the likelihood of gastrointestinal side effects like nausea. Taking it with food can also enhance its absorption.

What should I do if I forget a dose?

If you miss a dose of Cevimeline, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

What side effects can this medication cause?

Cevimeline, like any medication, can cause side effects. It’s important to be aware of these potential side effects and to discuss any concerns with your healthcare provider. Common side effects of Cevimeline may include:

• Excessive sweating: This is a common side effect of Cevimeline.
• Increased saliva production: Another common side effect is an increase in saliva production, which can sometimes be bothersome.
• Blurred vision: Cevimeline can cause blurred vision or other changes in vision.
• Nausea: Some people may experience nausea or stomach discomfort.
• Abdominal pain: This can occur as a side effect of Cevimeline.
• Headache: Headaches are another possible side effect.
• Dizziness: Cevimeline may cause dizziness or lightheadedness in some individuals.
• Runny nose: Some people may experience a runny nose as a side effect.
• Urinary frequency: Cevimeline can sometimes increase the frequency of urination.
• Difficulty breathing: In rare cases, Cevimeline may cause difficulty breathing or tightening of the throat.
• Chest pain: Chest pain can occur as a side effect, though this is less common.
• Skin reactions: It’s possible to experience skin reactions such as rash or itching.
• Muscle weakness: This is a rare side effect of Cevimeline.

If you experience any severe or persistent side effects while taking Cevimeline, or if you develop new symptoms that concern you, it’s important to notify your doctor immediately. They can help determine the appropriate course of action, which may include adjusting your dosage or considering alternative treatments.

What should I know about storage and disposal of this medication?

Storage and Disposal of Cevimeline:

• Storage: Store Cevimeline capsules at room temperature away from moisture and heat. Keep the medication in its original container or packaging to protect it from light and moisture.
• Keep Out of Reach of Children and Pets: Store Cevimeline in a secure place where children and pets cannot access it.
• Disposal: Dispose of unused or expired Cevimeline capsules properly according to local regulations or guidelines. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Consult your pharmacist or local waste disposal company for proper disposal instructions.

In case of emergency/overdose

• Seek Immediate Medical Attention: Contact emergency services (911) or your local poison control center (1-800-222-1222) immediately if you or someone else has taken more Cevimeline than prescribed or recommended.
• Symptoms of Overdose: Symptoms of Cevimeline overdose may include excessive sweating, increased saliva production, nausea, vomiting, diarrhea, difficulty breathing, blurred vision, dizziness, and possibly more severe symptoms depending on the amount ingested.
• Do Not Drive Yourself: If you suspect an overdose, do not attempt to drive yourself to seek medical help. Call emergency services for assistance.

What other information should I know?

• Regular Follow-up: Attend scheduled appointments with your doctor for regular check-ups and monitoring while taking Cevimeline.
• Medication Interactions: Inform all healthcare providers about your use of Cevimeline, including dentists, surgeons, and emergency medical personnel. Cevimeline can interact with certain medications, so it’s important for them to be aware of all the medications you are taking.
• Avoid Alcohol: Limit or avoid alcohol consumption while taking Cevimeline, as it can worsen certain side effects such as dizziness or drowsiness.
• Medical Alert: Consider wearing a medical alert bracelet or carrying a medical alert card indicating that you are taking Cevimeline. This can be helpful in case of emergencies where you may be unable to communicate.
• Educational Resources: Utilize educational resources provided by your healthcare provider or pharmacist to understand more about Cevimeline, its effects, and how to manage potential side effects.

By following these guidelines and staying informed about your medication, you can help ensure safe and effective use of Cevimeline as part of your treatment plan for dry mouth associated with Sjögren’s syndrome or other conditions as prescribed by your healthcare provider.