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Cedaprin (Generic Ibuprofen)

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WARNING

Nonsteroidal anti-inflammatory drugs (NSAIDs) other than aspirin, such ibuprofen, may increase a person’s chance of having a heart attack or stroke compared to a person who does not use them. These occurrences could be fatal and could occur suddenly. For those who take NSAIDs for an extended period of time, this risk may be larger. If you have recently experienced a heart attack, avoid taking an NSAID like ibuprofen unless your doctor specifically instructs you to. Inform your doctor if you smoke, have a history of heart disease, a heart attack, or a stroke, or if anybody in your family has experienced any of these. Also if you currently have or have ever had diabetes, high blood pressure, or high cholesterol. If you suffer any of the following symptoms, get emergency medical attention right away: chest pain, breathlessness, a weakness on one side or arm, or slurred speech.

Ibuprofen should not be taken either just before or just after having a coronary artery bypass graft (CABG; a form of heart surgery).

Ibuprofen and other NSAIDs are known to increase the risk of stomach or intestinal ulcers, bleeding, or holes. These issues can arise at any point during therapy, without any prior symptoms, and they have the potential to be fatal. Long-term NSAID users, the elderly, persons in poor health, and those who consume three or more alcoholic beverages per day while taking ibuprofen may be at higher risk. If you use any of the following medications, let your doctor know: Aspirin, other NSAIDs like ketoprofen and naproxen (Aleve, Naprosyn), oral steroids like dexamethasone, methylprednisolone (Medrol), and prednisone (Rayos), as well as anticoagulants (‘blood thinners’) like warfarin (Coumadin, Jantoven); selective serotonin reuptake inhibitors (SSRIs) include citalopram (Celexa), fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), and sertraline (Zoloft), as well as serotonin norepinephrine reuptake inhibitor (Effexor XR). Moreover, let your doctor know if you now or previously had an ulcer, gastrointestinal bleeding, or any other bleeding disorders. Call your doctor and stop taking ibuprofen if you notice any of the following symptoms: stomach pain, heartburn, bloody or coffee-ground-looking vomit, blood in the stool, or dark, tarry stools.

Keep all of your appointments with your physician and the lab. Your doctor will keep a close eye on your symptoms and most likely prescribe certain tests to determine how well your body is responding to ibuprofen. Inform your physician about your feelings so that they can prescribe the ideal dosage of medication to cure your problem with the least chance of negative side effects.

The manufacturer’s patient information sheet (Medication Guide) will be sent to you by your doctor or pharmacist when you start taking prescription ibuprofen and each time you refill your prescription. If you have any questions, carefully read the material and contact your doctor or pharmacist. The Medication Guide is also available on the manufacturer’s website or the Food and Drug Administration (FDA) website.

Why is this medication prescribed?

Prescription ibuprofen is used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints) and rheumatoid arthritis (arthritis caused by swelling of the lining of the joints). It is also used to relieve mild to moderate pain, including menstrual pain (pain that happens before or during a menstrual period). Nonprescription ibuprofen is used to reduce fever and to relieve minor aches and pain from headaches, muscle aches, arthritis, menstrual periods, the common cold, toothaches, and backaches. Ibuprofen is in a class of medications called NSAIDs. It works by stopping the body’s production of a substance that causes pain, fever, and inflammation.

How should this medicine be used?

Prescription ibuprofen comes as a tablet to take by mouth. It is usually taken three or four times a day for arthritis or every 4 to 6 hours as needed for pain. Nonprescription ibuprofen comes as a tablet, chewable tablet, suspension (liquid), and drops (concentrated liquid). Adults and children older than 12 years of age may usually take nonprescription ibuprofen every 4 to 6 hours as needed for pain or fever. Children and infants may usually be given nonprescription ibuprofen every 6 to 8 hours as needed for pain or fever, but should not be given more than 4 doses in 24 hours. Ibuprofen may be taken with food or milk to prevent stomach upset. If you are taking ibuprofen on a regular basis, you should take it at the same time(s) every day. Follow the directions on the package or prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take ibuprofen exactly as directed. Do not take more or less of it or take it more often than directed by the package label or prescribed by your doctor.

Ibuprofen comes alone and in combination with other medications. Some of these combination products are available by prescription only, and some of these combination products are available without a prescription and are used to treat cough and cold symptoms and other conditions. If your doctor has prescribed a medication that contains ibuprofen, you should be careful not to take any nonprescription medications that also contain ibuprofen.

Swallow the tablet whole; do not chew or crush it.

If you are selecting a product to treat cough or cold symptoms, ask your doctor or pharmacist for advice on which product is best for you. Check nonprescription product labels carefully before using two or more products at the same time. These products may contain the same active ingredient(s) and taking them together could cause you to receive an overdose. This is especially important if you will be giving cough and cold medications to a child.

Nonprescription cough and cold combination products, including products that contain ibuprofen, can cause serious side effects or death in young children. Do not give these products to children younger than 4 years of age. If you give these products to children 4 to 11 years of age, use caution and follow the package directions carefully.

If you are giving ibuprofen or a combination product that contains ibuprofen to a child, read the package label carefully to be sure that it is the right product for a child of that age. Do not give ibuprofen products that are made for adults to children.

Before you give an ibuprofen product to a child, check the package label to find out how much medication the child should receive. Give the dose that matches the child’s age on the chart. Ask the child’s doctor if you don’t know how much medication to give the child.

Shake the suspension and drops well before each use to mix the medication evenly. Use the measuring cup provided to measure each dose of the suspension, and use the dosing device provided to measure each dose of the drops.

The chewable tablets may cause a burning feeling in the mouth or throat. Take the chewable tablets with food or water.

Stop taking nonprescription ibuprofen and call your doctor if your symptoms get worse, you develop new or unexpected symptoms, the part of your body that was painful becomes red or swollen, your pain lasts for more than 10 days, or your fever lasts more than 3 days. Stop giving nonprescription ibuprofen to your child and call your child’s doctor if your child does not start to feel better during the first 24 hours of treatment. Also stop giving nonprescription ibuprofen to your child and call your child’s doctor if your child develops new symptoms, including redness or swelling on the painful part of his body, or if your child’s pain or fever get worse or lasts longer than 3 days.

Do not give nonprescription ibuprofen to a child who has a sore throat that is severe or does not go away, or that comes along with fever, headache, nausea, or vomiting. Call the child’s doctor right away, because these symptoms may be signs of a more serious condition.

Other uses for this medicine

Ibuprofen is also sometimes used to treat ankylosing spondylitis (arthritis that mainly affects the spine), gouty arthritis (joint pain caused by a build-up of certain substances in the joints), and psoriatic arthritis (arthritis that occurs with a long-lasting skin disease that causes scaling and swelling). Talk to your doctor about the risks of using this drug for your condition.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking ibuprofen,

  • Inform your physician and pharmacist if you have any allergies to ibuprofen, aspirin, other NSAIDs including naproxen (Aleve, Naprosyn), ketoprofen, or any of the inactive components in the brand of ibuprofen you intend to use. For a list of the inactive substances, consult your pharmacist or the box label.
  • Inform your doctor and pharmacist about any vitamins, nutritional supplements, herbal items, and prescription and over-the-counter medicines you are now taking or intend to take. Mention any of the following as well as the medications specified in the IMPORTANT WARNING section. moexipril (Univasc), perindopril (Aceon, in Prestalia), quinapril (Accupril, in Quinaretic), ramipril (Altace), and trandolapril (Mavik, in Tarka) are examples of angiotensin-converting enzyme (ACE) inhibitors. Other examples include captopril, enalapril, fosinopril, and lisinopril (in Zestoretic); candesartan (Atacand, Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, in Avalide), losartan (Cozaar, in Hyzaar), olmesartan (Benicar, in Azor, in Benicar HCT, in Tribenzor), telmisartan (Micardis, in Micardis HCT, in Twynsta), and valsartan (in Exforge HCT); atenolol (Tenormin, Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, in Dutoprol), nadolol (Corgard, in Corzide), and propranolol (Hemangeol, Inderal, and Innopran); diuretics (‘water pills’); lithium (Lithobid); and methotrexate are beta block (Otrexup, Rasuvo, Trexall). Your physician might need to adjust the dosage of your drugs or keep a closer eye on you for adverse effects.
  • Ibuprofen without a prescription should not be taken with any other painkillers unless your doctor specifically instructs you to.
  • Inform your doctor if you have or have ever had asthma, any of the conditions listed in the IMPORTANT WARNING section, heart failure, swelling in the hands, arms, feet, ankles, or lower legs, lupus (a condition in which the body attacks many of its own tissues and organs, frequently the skin, joints, blood, and kidneys), or liver or kidney disease. This is especially important if you also have frequent stuffy or runny nose, nasal polyps (swelling If you are providing ibuprofen to a child, let the doctor know if they haven’t been getting enough fluids or if they’ve lost a lot of fluid through frequent vomiting or diarrhoea.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. If ibuprofen is consumed after 20 weeks of pregnancy, it may harm the foetus and complicate delivery. Ibuprofen should not be taken during or after the first 20 weeks of pregnancy unless specifically advised to do so by your doctor. Call your doctor if you become pregnant while taking ibuprofen.
  • Inform your doctor or dentist that you are taking ibuprofen if you are undergoing surgery, including dental surgery.
  • If you are 75 years of age or older, discuss the advantages and disadvantages of taking ibuprofen with your doctor. Never use this medication for a longer time or at a higher dose than what is suggested by the manufacturer or your physician.
  • When taking ibuprofen without a prescription, carefully read the package label if you have phenylketonuria (PKU), a genetic illness that requires adherence to a particular diet to prevent brain damage that could result in severe intellectual incapacity. Aspartame, a phenylalanine source, may be used to sweeten some nonprescription forms of ibuprofen.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What should I do if I forget a dose?

Take the missing dose of ibuprofen as soon as you remember it if you regularly take it. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Ibuprofen could have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Constipation
  • Bloating, gas, or diarrhoea
  • Dizziness
  • Nervousness
  • Hearing ringing

Some adverse effects may be severe. Call your doctor right away if you notice any of the symptoms listed below or those described in the IMPORTANT CAUTION section. Unless you speak with your doctor, stop taking ibuprofen.

  • Rise in weight without cause
  • Respiratory issues or lack of breath
  • Abdomen, lower legs, or foot and ankles swelling
  • Fever
  • Blisters
  • Rash
  • Itching
  • Hives
  • Swelling of the hands, arms, hands, face, throat, or eyes
  • Breathing or swallowing challenges
  • Hoarseness
  • Extreme fatigue
  • Stomach ache in the top right corner
  • Nausea
  • Reduced appetite
  • Eyes or skin that have a yellow tint
  • Flu-like signs
  • Light skin
  • Rapid heart rate
  • Urine that is hazy, discoloured, or bloody
  • Back ache
  • Uncomfortable or challenging urinating
  • Visual issues such as blurriness, colour shifts, or others
  • Red or hurting eyes
  • Tense neck
  • Headache
  • Confusion
  • Aggression

Further negative effects of ibuprofen are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Keep it away from excessive heat and moisture at room temperature (not in the bathroom).

Although many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning. http://www.upandaway.org

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medications website at http://goo.gl/c4Rm4p for additional information.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Overdosage symptoms could include:

  • Dizziness
  • Rapid, uncontrollable eye motions
  • Breathing slowly or stopping for brief durations of time
  • Lips, mouth, and nose are all outlined in blue.

What other information should I know?

Don’t let anyone else use your ibuprofen if it is a prescription drug. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Addaprin®
  • Advil®
  • Cedaprin®
  • I-Prin®
  • Midol®
  • Motrin®
  • Motrin® IB
  • NeoProfen®
  • Profen IB®
  • Proprinal®
  • Ultraprin®
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