Why is this medication prescribed?

Cardura XL is a prescription medication primarily prescribed to treat high blood pressure (hypertension) and symptoms of benign prostatic hyperplasia (BPH), a condition in which the prostate gland becomes enlarged, causing problems with urination.

• Hypertension: Cardura XL helps to lower blood pressure by relaxing blood vessels so that blood can flow more easily.
• Benign Prostatic Hyperplasia (BPH): It helps to relax muscles in the prostate and bladder neck, making it easier to urinate.

How should this medicine be used?

Cardura XL is usually taken once daily, typically in the morning with breakfast or the first main meal of the day. It’s important to swallow the tablet whole with a sufficient amount of water and not to crush, chew, or break it. Breaking the tablet could release too much of the drug at once, increasing the risk of side effects.

Dosage is typically started low and adjusted by your healthcare provider based on your response to the medication. It’s crucial to follow your doctor’s instructions carefully and not to stop taking Cardura XL without consulting them, even if you feel well.

If you miss a dose, take it as soon as you remember. However, if it is near the time of your next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Always discuss any questions or concerns about Cardura XL with your healthcare provider, especially regarding potential side effects, interactions with other medications or supplements, and the duration of treatment.

Other uses for this medicine

Some potential off-label uses of Cardura XL might include:

• Raynaud’s Disease: This condition causes narrowing of blood vessels in the extremities (such as fingers and toes), leading to reduced blood flow and pain. Cardura XL’s ability to relax blood vessels could potentially help in managing symptoms.
• Heart Failure: In some cases, Cardura XL may be used alongside other medications to manage heart failure, particularly to reduce blood pressure and improve blood flow.
• Post-Traumatic Stress Disorder (PTSD): Some studies have explored the use of alpha-blockers like doxazosin (the active ingredient in Cardura XL) in managing symptoms of PTSD, such as nightmares and hyperarousal.

What special precautions should I follow?

Special Precautions for Cardura XL:

• Hypotension: Cardura XL can cause a sudden drop in blood pressure, especially when standing up quickly from a sitting or lying position (postural hypotension). To minimize this risk, it’s important to take the medication as prescribed and to monitor your blood pressure regularly.
• First Dose Effect: When starting Cardura XL or increasing the dose, there is a risk of experiencing a sudden drop in blood pressure, which may cause dizziness or fainting. This is more common with the first dose and can be minimized by starting with a low dose and gradually increasing it under medical supervision.
• Prostate Cancer: Before starting Cardura XL for symptoms of BPH, your healthcare provider should rule out prostate cancer, as Cardura XL can mask symptoms of this condition.
• Liver Function: Cardura XL is metabolized by the liver, so individuals with liver impairment may require dose adjustments or closer monitoring.
• Interactions: Cardura XL may interact with other medications, including erectile dysfunction drugs (like sildenafil), other blood pressure medications, and medications for erectile dysfunction. It’s important to inform your healthcare provider about all medications you are taking.
• Pregnancy and Breastfeeding: Cardura XL is not typically used in women, especially during pregnancy and breastfeeding, unless the potential benefits outweigh the risks.
• Allergic Reactions: If you have a known allergy to doxazosin or any other ingredients in Cardura XL, you should not take this medication.

Always follow your healthcare provider’s instructions and advice regarding the use of Cardura XL, including any precautions specific to your individual health condition and medical history. Regular monitoring and communication with your doctor are essential for safe and effective treatment.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Cardura XL. However, maintaining a healthy diet low in sodium and saturated fats can complement the treatment of hypertension and other cardiovascular conditions. It’s important to follow any dietary recommendations provided by your healthcare provider to manage your overall health effectively.

What should I do if I forget a dose?

If you forget to take your dose of Cardura XL at the scheduled time, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Cardura XL (doxazosin extended-release) can cause various side effects, some of which are common and others that are less common but more serious. It’s important to be aware of these potential side effects and to promptly report any unusual symptoms to your healthcare provider. Here are some of the side effects associated with Cardura XL:

Common Side Effects:

• Dizziness: Especially when standing up quickly (postural hypotension).
• Fatigue: Feeling tired or lethargic.
• Headache: Mild to moderate headaches.
• Edema: Swelling in the hands, ankles, or feet.
• Nasal Congestion: Stuffy or runny nose.
• Nausea: Feeling like you might vomit.
• Dry Mouth: Reduced saliva production.
• Weakness: Generalized weakness or fatigue.
• Low Blood Pressure: Especially noticeable when first starting the medication.

Less Common but Serious Side Effects:

• Fainting: Especially with the first dose or when standing up quickly.
• Irregular Heartbeat: Palpitations or changes in heart rhythm.
• Priapism: A painful erection that lasts for more than 4 hours (seek immediate medical attention if this occurs).
• Severe Allergic Reaction: Symptoms may include rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.

Other Potential Side Effects:

• Vision Changes: Blurred vision or other visual disturbances.
• Urinary Symptoms: Changes in urination patterns.
• Back Pain: Discomfort in the back area.
• Gastrointestinal Issues: Upset stomach, diarrhea, or constipation.
• Mood Changes: Anxiety or depression (rare).
• Liver Problems: Jaundice (yellowing of the skin or eyes).

Important Considerations:

• Drug Interactions: Cardura XL may interact with other medications, including those for erectile dysfunction (like sildenafil), causing an increased risk of low blood pressure.
• Pre-existing Conditions: Individuals with liver disease or kidney disease may experience more severe side effects.
• First Dose Effect: There is a risk of experiencing a sudden drop in blood pressure with the first dose or after a dose increase.

Always discuss any concerns about side effects with your healthcare provider. They can provide guidance on managing side effects and may adjust your treatment plan if needed to minimize discomfort or risk. If you experience any severe or concerning side effects, seek medical attention promptly.

What should I know about storage and disposal of this medication?

Storage and Disposal of Cardura XL:

• Storage: Store Cardura XL tablets at room temperature, away from moisture and heat. Keep the medication in its original packaging or container to protect it from light and moisture.
• Disposal: Dispose of unused or expired Cardura XL tablets safely. Follow any specific disposal instructions provided by your healthcare provider or pharmacist. Do not flush medications down the toilet unless instructed to do so. Proper disposal helps prevent accidental ingestion by children, pets, or others.

In case of emergency/overdose

• Emergency: In case of a severe reaction or suspected overdose, such as extreme dizziness, fainting, difficulty breathing, or prolonged erection (priapism), seek immediate medical attention by calling emergency services (911 in the US).
• Overdose: Symptoms of overdose may include severe dizziness, weakness, fainting, or dangerously low blood pressure. If you suspect an overdose, contact your local poison control center at 1-800-222-1222 (in the US) or go to the nearest emergency room immediately.

What other information should I know?

• Regular Monitoring: Your healthcare provider may monitor your blood pressure regularly while you are taking Cardura XL to ensure it is effectively managing your condition.
• Diet and Lifestyle: Alongside medication, maintaining a healthy diet, managing stress, regular exercise, and avoiding smoking and excessive alcohol intake can help improve overall health and support the effectiveness of Cardura XL in managing hypertension or benign prostatic hyperplasia.
• Follow-up Visits: Attend scheduled follow-up visits with your healthcare provider to assess your response to Cardura XL and make any necessary adjustments to your treatment plan.
• Inform Healthcare Providers: Always inform other healthcare providers, including dentists and surgeons, that you are taking Cardura XL. This medication can interact with anesthesia and other medications used during procedures.
• Educational Resources: It’s essential to educate yourself about Cardura XL, including its purpose, potential side effects, and what to do in case of missed doses or side effects.

By following these guidelines and staying informed about Cardura XL, you can manage your medication safely and effectively with guidance from your healthcare provider.