Why is this medication prescribed?

Calcipotriol is prescribed primarily for the treatment of psoriasis, a chronic autoimmune skin condition characterized by red, scaly patches on the skin. It is a synthetic derivative of vitamin D that helps to control the excessive production of skin cells and reduce inflammation associated with psoriasis.

How should this medicine be used?

How Calcipotriol should be used:

• Application: Calcipotriol is typically available as a topical ointment or cream. It should be applied directly to the affected areas of the skin.
• Frequency: The frequency of application can vary depending on the severity of the condition and the formulation prescribed by the doctor. Usually, it is applied once or twice daily.
• Amount: Use enough to thinly cover the affected area(s). Avoid using excessive amounts unless directed by your doctor.
• Precautions: Wash hands after applying unless the hands are the treated area. Avoid contact with eyes and mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not apply to broken, infected, or severely inflamed skin unless directed by your doctor.
• Usage duration: Follow the prescribed duration of use as directed by your doctor. Typically, treatment with calcipotriol may be continued for several weeks to months, depending on the response and severity of psoriasis.
• Monitoring: Regular follow-up with your doctor is important to monitor the effectiveness of the treatment and to adjust the dosage or treatment plan if necessary.

It’s crucial to use calcipotriol exactly as prescribed by your healthcare provider to achieve the best results while minimizing potential side effects.

Other uses for this medicine

Here are some potential alternative uses:

• Vitiligo: Calcipotriol may be used off-label in the treatment of vitiligo, a condition where patches of skin lose their pigment.
• Ichthyosis: It has been studied for its potential benefits in certain types of ichthyosis, which are genetic disorders that result in dry, scaly skin.
• Other hyperproliferative skin disorders: There have been explorations into the use of calcipotriol for conditions such as palmoplantar keratoderma and lichen planus, although evidence and guidelines for these uses may vary.

What special precautions should I follow?

When using calcipotriol, it’s important to follow these precautions:

• Avoid excessive exposure to sunlight: Calcipotriol can make your skin more sensitive to sunlight, leading to an increased risk of sunburn. Use sunscreen and protective clothing when outdoors.
• Avoid use on the face and mucous membranes: Unless specifically instructed by your doctor, avoid applying calcipotriol on the face, in skin folds, or on mucous membranes (such as inside the nose, mouth, or genital areas).
• Avoid use on broken or irritated skin: Do not apply calcipotriol to areas of the skin that are broken, infected, or severely inflamed, unless directed by your doctor.
• Pregnancy and breastfeeding: If you are pregnant or breastfeeding, consult with your healthcare provider before using calcipotriol. While topical use generally results in minimal systemic absorption, it’s important to discuss potential risks and benefits.
• Potential interactions: Inform your doctor about all medications you are taking, including over-the-counter drugs and supplements, to avoid potential interactions with calcipotriol.
• Monitoring: Regular follow-up with your doctor is important to monitor the response to treatment and to assess any potential side effects or complications.

By following these precautions and using calcipotriol as directed by your healthcare provider, you can help ensure safe and effective treatment for your skin condition.

What special dietary instructions should I follow?

There are typically no specific dietary restrictions associated with the use of calcipotriol. However, it’s always beneficial to maintain a healthy diet rich in vitamins and minerals, which can support overall skin health.

What should I do if I forget a dose?

If you miss a dose of calcipotriol, apply it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra medication to make up for a missed dose.

What side effects can this medication cause?

Calcipotriol, when used as directed, is generally well-tolerated. However, like any medication, it can cause side effects in some individuals. Here are some potential side effects associated with calcipotriol:

• Skin Irritation: This is the most common side effect, including redness, itching, burning, dryness, or peeling of the skin at the application site. These effects are usually mild and may improve as your skin adjusts to the medication.
• Transient Hypercalcemia: In rare cases, especially if large areas of the body are treated or if occlusive dressings are used, calcipotriol can be absorbed through the skin into the bloodstream, potentially leading to elevated calcium levels (hypercalcemia). Symptoms of hypercalcemia may include nausea, vomiting, increased thirst, increased urination, weakness, fatigue, and confusion.
• Skin Hypopigmentation: Prolonged use of calcipotriol can rarely cause lightening of the skin at the application site.
• Allergic Reactions: Although uncommon, allergic reactions such as rash, hives, or swelling may occur. If you experience any signs of a serious allergic reaction, such as severe dizziness or difficulty breathing, seek medical attention immediately.
• Eye Irritation: Accidental exposure of calcipotriol to the eyes can cause irritation. Rinse thoroughly with water if this occurs.
• Exacerbation of Psoriasis: In some cases, calcipotriol may initially cause a temporary worsening of psoriasis symptoms before improvement is seen.
• Others: Less commonly, other side effects such as folliculitis (inflammation of hair follicles), dermatitis, or worsening of existing skin conditions may occur.

It’s important to discuss any concerns or potential side effects with your healthcare provider. They can provide guidance on managing side effects and determine if calcipotriol is the best treatment option for your condition. If you experience severe or persistent side effects, contact your doctor promptly.

What should I know about storage and disposal of this medication?

Storage and Disposal of Calcipotriol:

• Storage:
  • Store calcipotriol ointment or cream at room temperature, away from moisture and heat.
  • Keep the tube tightly closed when not in use.
  • Keep out of reach of children and pets.
• Disposal:
  • Dispose of calcipotriol as per local regulations or guidelines.
  • Do not flush medications down the toilet or pour them into a drain unless instructed to do so.
  • If in doubt, consult with your pharmacist or healthcare provider on the proper disposal method.

In case of emergency/overdose

• Accidental Ingestion: If calcipotriol is accidentally ingested, seek medical attention immediately or contact a poison control center right away. Do not induce vomiting unless instructed to do so by medical personnel.
• Symptoms of Overdose: Symptoms of calcipotriol overdose may include symptoms of hypercalcemia (elevated blood calcium levels) such as nausea, vomiting, increased thirst, increased urination, weakness, fatigue, and confusion. If you experience any of these symptoms after using calcipotriol, contact your healthcare provider promptly.

What other information should I know?

• Follow Instructions: Use calcipotriol exactly as prescribed by your healthcare provider. Do not use more than recommended or for longer than prescribed.
• Sun Protection: Avoid excessive sun exposure and use sunscreen on treated areas, as calcipotriol can increase sensitivity to sunlight.
• Regular Monitoring: Attend follow-up appointments with your healthcare provider to monitor your condition and the effectiveness of treatment.
• Potential Interactions: Inform your doctor about all medications you are taking, including over-the-counter drugs and supplements, to avoid potential interactions.
• Avoid Eye Contact: Avoid getting calcipotriol ointment or cream in your eyes. If accidental eye contact occurs, rinse thoroughly with water.
• Pregnancy and Breastfeeding: Consult your doctor before using calcipotriol if you are pregnant, planning to become pregnant, or breastfeeding. Your doctor will assess the risks and benefits of treatment during these times.
• Handling Precautions: Wash hands thoroughly after applying calcipotriol, unless the hands are the treated area.

By following these guidelines and understanding these aspects of calcipotriol use, you can ensure safe and effective treatment of your skin condition. If you have any further questions or concerns, don’t hesitate to discuss them with your healthcare provider or pharmacist.