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Bystolic (Generic Nebivolol)

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Why is this medication prescribed?

Nebivolol is used to treat high blood pressure either alone or in combination with other drugs. Nebivolol belongs to a group of drugs called beta blockers. It improves blood flow and lowers blood pressure by relaxing blood vessels and lowering heart rate.

High blood pressure is a common illness that, if left untreated, can harm the kidneys, brain, heart, blood vessels, and other organs. Heart disease, a heart attack, heart failure, a stroke, renal failure, eyesight loss, and other issues may result from damage to these organs. Making lifestyle modifications will help you control your blood pressure in addition to taking medication. These adjustments include quitting smoking, drinking alcohol in moderation, eating a diet low in fat and salt, keeping a healthy weight, and exercising for at least 30 minutes most days.

How should this medicine be used?

Nebivolol is available as an oral tablet. It is typically taken once day, with or without food. Nebivolol should be taken at roughly the same time each day to help you remember to take it. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Nebivolol should be taken as prescribed. Never take it in larger or less amounts or more frequently than directed by your doctor.

Nebivolol may be prescribed to you at a low dosage by your doctor, who will then progressively raise it up to once every two weeks.

Although it doesn’t treat high blood pressure, nebivolol does moderate it. Before nebivolol’s full benefits are evident in blood pressure readings, it could take two weeks. Even if you feel good, keep taking nebivolol. Nebivolol should not be stopped without first consulting your doctor. Nebivolol withdrawal symptoms include angina (chest discomfort), heart attack, and irregular pulse if you suddenly stop taking medication. Over the course of one to two weeks, your doctor will likely progressively reduce your dosage.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before taking nebivolol,

  • If you have an allergy to nebivolol, any other medications, or any of the ingredients in nebivolol tablets, tell your doctor and pharmacist right away. Request a list of the components from your pharmacist.
  • Inform your doctor and pharmacist about any vitamins, nutritional supplements, herbal items, and prescription and over-the-counter medicines you are now taking or intend to take. Any of the following should be mentioned: acebutolol (Sectral); atenolol (Tenormin, in Tenoretic); betaxolol; bisoprolol (Zebeta, in Ziac); carvedilol (Coreg); labetalol; metoprolol (Lopressor, Toprol XL); nadolol (Corgard, in Corzide); pindolo; propranolol (Inderal, InnoPran XL, in Inderide); chlorpheniramine (antihistamine in allergy and cold drugs), cimetidine, clomipramine (Anafranil), clonidine (Catapres, Kapvay, in Clorpres), digoxin (Lanoxin), disopyramide (Norpace), calcium channel blockers such as diltiazem (Cardizem, Dilacor, others) and verapamil (Calan, Covera, Isoptin, in Tarka); haloperidol (Haldol), fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax), methadone (Dolophine, Methadose), paroxetine (Paxil), propafenone (Rythmol), quinidine, reserpine, ritonavir (Norvir, in Kaletra), sildenafil, insulin, oral diabetes medicines, and sil (Revatio, Viagra). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • If you have heart failure, liver illness, a slow heartbeat, or any of these conditions, let your doctor know. Nebivolol may not be taken, according to your doctor.
  • Inform your physician if you have or have had had diabetes, hyperthyroidism (an overactive thyroid gland), circulatory issues, kidney disease, severe allergies, or pheochromocytoma (a tumour that develops on a gland near the kidneys and may cause high blood pressure and fast heart rate).
  • If you are breastfeeding a child or intend to become pregnant, let your doctor know. Call your doctor if you become pregnant while taking nebivolol.
  • Inform your doctor or dentist that you are taking nebivolol if you are undergoing surgery, including dental surgery.
  • Nebivolol has the potential to make you sleepy, so be aware of it. Prior to understanding how this drug affects you, avoid using machinery or driving a car.
  • You should be aware that if you are allergic to various chemicals, using nebivolol may make your symptoms worse and that standard doses of injectable epinephrine may not be effective in treating your allergies.

What special dietary instructions should I follow?

If your doctor advises a low-salt or low-sodium diet, carefully follow their instructions.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Nebivolol’s negative effects could occur. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Headache
  • Tiredness
  • Weakness
  • Dizziness
  • Diarrhea
  • Nausea
  • Abdominal pain
  • Having trouble falling or staying asleep
  • Hands, arms, feet, or legs that are numb, burning, or tingly

Some adverse effects can be very harmful. Even though the following signs are unusual, you should call your doctor right once if you notice any of them:

  • Chest pain
  • Sluggish heartbeat
  • Having trouble breathing
  • Unexpected weight gain
  • Rash
  • Hands, foot, ankles, or lower legs swelling

Other negative effects of nebivolol are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Store it away from excessive heat and moisture at room temperature (not in the bathroom).

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at for additional information.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Overdose signs could include the following:

  • Sluggish heartbeat
  • Fainting or vertigo
  • Shakiness
  • Sweating
  • Confusion
  • Anxiety, impatience, or abrupt changes in attitude or behaviour
  • Headache
  • Tingling or numbness in the mouth
  • Weakness
  • Light skin
  • Abrupt hunger
  • Ungainly or jerky motions
  • Having trouble breathing
  • Seizures
  • Tiredness
  • Vomiting

What other information should I know?

Do not miss any of your doctor’s appointments. The effectiveness of nebivolol should be monitored by routine blood pressure checks. You may be asked by your doctor to check your pulse (heart rate). Ask your doctor or pharmacist to show you how to take your pulse. Call your doctor if your pulse is either quicker or slower than it should be.

Inform the lab staff and your doctor that you are taking nebivolol prior to any laboratory test.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Bystolic®
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