WARNING

Brovana (arformoterol) is a medication primarily used to treat chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. While it can be effective in managing symptoms and improving lung function, there are potential risks associated with its use.

• Cardiovascular Effects: Brovana can cause an increase in heart rate and blood pressure, which may pose risks for individuals with certain cardiovascular conditions such as heart rhythm disorders or hypertension.
• Bronchospasm: In some cases, Brovana can paradoxically cause bronchospasm, making breathing more difficult instead of improving it. This is more likely to occur in people with asthma.
• Hypokalemia: Brovana can lower potassium levels in the blood, which may lead to muscle weakness, irregular heartbeats, or other symptoms. Regular monitoring of potassium levels may be necessary during treatment.
• Interactions with other Medications: Brovana may interact with other medications, especially other beta-adrenergic bronchodilators or medications that affect heart rate or blood pressure. It’s essential to inform your healthcare provider about all medications you’re taking to avoid potential interactions.
• Worsening of COPD: While Brovana is used to manage COPD symptoms, in some cases, it may not be effective or may even worsen symptoms. If you notice your COPD symptoms worsening despite treatment, contact your healthcare provider.
• Allergic Reactions: Some individuals may experience allergic reactions to Brovana, characterized by symptoms such as rash, itching, swelling, or difficulty breathing. Seek medical attention immediately if you experience any signs of an allergic reaction.

It’s crucial to discuss the potential risks and benefits of Brovana with your healthcare provider before starting treatment, especially if you have any pre-existing medical conditions or are taking other medications. Regular monitoring and open communication with your healthcare team can help mitigate risks and ensure safe and effective treatment.

Why is this medication prescribed?

Brovana (arformoterol) is prescribed primarily for the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. It belongs to a class of medications known as long-acting beta agonists (LABAs), which help to relax and open the airways in the lungs, making breathing easier.

Brovana is typically prescribed for individuals with COPD who require maintenance treatment to alleviate symptoms such as shortness of breath, coughing, and wheezing. It is not a rescue medication for sudden breathing problems and should not be used to treat acute episodes of bronchospasm.

How should this medicine be used?

Brovana comes in the form of a nebulizer solution and should be administered via a nebulizer machine. The usual dose is 15 mcg (one vial) of Brovana administered twice daily (morning and evening) approximately 12 hours apart.

Here’s how Brovana should be used:

• Prepare the Nebulizer: Follow the manufacturer’s instructions for assembling and preparing the nebulizer machine.
• Measure the Dose: Open one vial of Brovana and pour the entire contents into the medication chamber of the nebulizer.
• Administer the Medication: Sit or stand in an upright position and place the mouthpiece of the nebulizer in your mouth. Breathe in and out normally through the mouthpiece until the medication is completely administered, which usually takes about 5 to 10 minutes.
• Clean the Nebulizer: After each use, thoroughly clean the nebulizer according to the manufacturer’s instructions to prevent contamination and ensure proper functioning for the next use.
• Use Regularly: Use Brovana regularly, as prescribed by your healthcare provider, even if you are feeling well. Do not increase or decrease the dose or frequency of use without consulting your doctor.
• Follow-up: Attend regular follow-up appointments with your healthcare provider to monitor your response to Brovana and make any necessary adjustments to your treatment plan.

It’s essential to use Brovana exactly as prescribed by your healthcare provider to achieve the maximum benefit and reduce the risk of side effects. If you have any questions or concerns about how to use Brovana or its effects, don’t hesitate to consult your healthcare provider.

Other uses for this medicine

While Brovana (arformoterol) is primarily prescribed for the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema, it may have off-label uses or be investigated for other respiratory conditions. However, it’s important to note that using Brovana for any condition not approved by the FDA (off-label use) should only be done under the guidance and supervision of a healthcare provider.

What special precautions should I follow?

Special precautions should be taken when using Brovana, and it’s essential to follow your healthcare provider’s instructions closely. Here are some key precautions to consider:

• Medical History: Before using Brovana, inform your healthcare provider about your complete medical history, including any pre-existing conditions such as heart disease, high blood pressure, diabetes, thyroid disorders, seizures, or liver disease.
• Medication Interactions: Inform your healthcare provider about all medications, supplements, and herbal products you are currently taking, as Brovana may interact with certain medications, including other beta-adrenergic bronchodilators, monoamine oxidase inhibitors (MAOIs), and tricyclic antidepressants.
• Allergies: If you have a history of allergies to arformoterol or any other ingredients in Brovana, inform your healthcare provider before starting treatment.
• Cardiovascular Effects: Brovana can cause an increase in heart rate and blood pressure, which may pose risks for individuals with certain cardiovascular conditions. Your healthcare provider may monitor your heart rate and blood pressure regularly during treatment.
• Potassium Levels: Brovana may lower potassium levels in the blood (hypokalemia). Your healthcare provider may perform regular blood tests to monitor your potassium levels and adjust your treatment accordingly.
• Paradoxical Bronchospasm: In some cases, Brovana may cause bronchospasm, making breathing more difficult instead of improving it. If you experience worsening breathing symptoms after using Brovana, seek medical attention immediately.
• Pregnancy and Breastfeeding: It’s essential to discuss the risks and benefits of using Brovana during pregnancy or breastfeeding with your healthcare provider. The potential risks to the fetus or infant should be carefully considered.
• Driving and Operating Machinery: Brovana may cause dizziness or blurred vision in some individuals. Avoid driving or operating machinery until you know how Brovana affects you.
• Regular Monitoring: Attend regular follow-up appointments with your healthcare provider to monitor your response to Brovana and address any concerns or side effects that may arise.
• Emergency Use: Brovana should not be used as a rescue medication for sudden breathing problems or acute episodes of bronchospasm. Ensure you have a fast-acting rescue inhaler prescribed by your healthcare provider for such situations.

Always consult your healthcare provider if you have any questions or concerns about using Brovana or if you experience any unexpected symptoms or side effects during treatment.

What special dietary instructions should I follow?

Regarding dietary instructions for Brovana, there are no specific dietary restrictions associated with its use. However, maintaining a balanced diet rich in fruits, vegetables, whole grains, and lean proteins can support overall health and may complement COPD management.

What should I do if I forget a dose?

If you forget to take a dose of Brovana, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one. If you have any concerns or questions about missed doses, consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Brovana (arformoterol) can cause side effects, although not everyone experiences them. Common side effects may include:

• Tremor: Shaking or trembling, especially in the hands, may occur.
• Nervousness or Anxiety: Some individuals may feel jittery or anxious after taking Brovana.
• Headache: Mild to moderate headaches are possible side effects.
• Dizziness: Feeling lightheaded or dizzy may occur, especially when standing up quickly.
• Muscle Cramps: Some people may experience muscle cramps or muscle pain.
• Insomnia: Difficulty falling asleep or staying asleep may occur.
• Increased Heart Rate: Brovana can cause an increase in heart rate (tachycardia).
• Nausea or Vomiting: Some individuals may experience nausea or vomiting.
• Cough or Sore Throat: Irritation in the throat or coughing may occur as a side effect.
• Hypokalemia: Brovana may lower potassium levels in the blood, which can lead to symptoms such as weakness, muscle cramps, or irregular heartbeats.
• Paradoxical Bronchospasm: In rare cases, Brovana may cause bronchospasm, making breathing more difficult instead of improving it.
• Allergic Reactions: Allergic reactions to Brovana are possible, though rare. Symptoms may include rash, itching, swelling, or difficulty breathing.

It’s important to note that this is not a complete list of side effects associated with Brovana. Some people may experience other side effects not listed here. If you experience any unusual or bothersome symptoms while taking Brovana, contact your healthcare provider for advice. If you experience severe or life-threatening side effects, seek immediate medical attention.

What should I know about storage and disposal of this medication?

Storage and disposal instructions for Brovana:

• Storage: Store Brovana vials in the foil pouch provided at room temperature between 68°F to 77°F (20°C to 25°C). Protect from light and moisture. Keep the vials out of reach of children.
• Disposal: Dispose of used vials and any unused medication according to local regulations or guidelines provided by your healthcare provider or pharmacist. Do not flush medications down the toilet unless instructed to do so. Properly discard Brovana in a sealed container or through a medication take-back program if available.

In case of emergency/overdose

• Seek Medical Assistance: If you suspect an overdose or experience severe symptoms such as chest pain, irregular heartbeats, seizures, or difficulty breathing, seek immediate medical attention or contact your local poison control center.
• Symptom Management: Follow any instructions provided by medical professionals for managing symptoms of overdose. Treatment may include supportive care to address symptoms and stabilize vital signs.

What other information should I know?

• Use as Directed: Take Brovana exactly as prescribed by your healthcare provider. Do not increase or decrease the dose or frequency of use without consulting them first.
• Regular Monitoring: Attend regular follow-up appointments with your healthcare provider to monitor your response to Brovana and make any necessary adjustments to your treatment plan.
• Avoid Triggering Factors: Minimize exposure to known triggers of COPD exacerbations, such as cigarette smoke, air pollution, allergens, and respiratory infections, to optimize the effectiveness of Brovana.
• Emergency Plan: Have a written COPD action plan provided by your healthcare provider, which outlines steps to take in case of worsening symptoms or exacerbations. This may include instructions for using rescue medications and seeking medical assistance.
• Medication Compliance: Take Brovana consistently and as prescribed, even if you are feeling well. Do not stop taking it without consulting your healthcare provider.
• Allergic Reactions: If you experience symptoms of an allergic reaction to Brovana, such as rash, itching, swelling, or difficulty breathing, seek medical attention immediately.
• Medication Interactions: Inform your healthcare provider about all medications, supplements, and herbal products you are currently taking to avoid potential interactions with Brovana.
• Pregnancy and Breastfeeding: Discuss the risks and benefits of using Brovana during pregnancy or breastfeeding with your healthcare provider. The potential risks to the fetus or infant should be carefully considered.
• Driving and Operating Machinery: Brovana may cause dizziness or blurred vision in some individuals. Avoid driving or operating machinery until you know how Brovana affects you.
• Follow-up Care: Continue to follow up with your healthcare provider for ongoing management of your COPD and adjustment of your treatment plan as needed.