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Brivaracetam

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Why is this medication prescribed?

Brivaracetam is used both by itself and in conjunction with other drugs to treat partial onset seizures (seizures that affect only a portion of the brain) in adults, kids, and babies older than one month. Anticonvulsants are a class of drugs that includes brivaracetam. It functions by reducing the brain’s aberrant electrical activity.

How should this medicine be used?

Brivaracetam is available as a tablet and a solution (liquid) for oral use. It is often taken twice daily, with or without food. Take brivaracetam daily at roughly the same time. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following.

Do not chew, break, or crush the tablets; instead, swallow them whole.

Do not measure your dose if you are consuming the drink with a regular spoon. Use a spoon designed specifically for measuring medication, the measuring cup that came with it, or both.

Depending on how well the drug works for you and the adverse effects you encounter, your doctor may raise or decrease your dose. Tell your doctor how you are feeling while receiving brivaracetam therapy.

Brivaracetam could cause addiction. Don’t take the medication in excess of what your doctor has suggested in terms of dosage, frequency, or duration.

Although it won’t treat your problem, brivaracetam may help you manage it. Brivaracetam should still be used even if you feel fine. Even if you encounter adverse effects such strange changes in behaviour or mood, you should not discontinue taking brivaracetam without first consulting your doctor. Your seizures can worsen if you abruptly stop using brivaracetam. Your dose will likely be gradually reduced by your doctor.

The patient information sheet (Medication Guide) from the manufacturer will be sent to you by your doctor or pharmacist when you start taking brivaracetam and each time you get a prescription refill. If you have any questions, carefully read the material and contact your doctor or pharmacist. The Medication Guide is also available on the manufacturer’s website or the Food and Drug Administration (FDA) website.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before taking brivaracetam,

  • If you have an allergy to brivaracetam, any other medications, or any of the ingredients in brivaracetam tablets or liquid, let your doctor and pharmacist know right away. For a list of the ingredients, consult the Medication Guide or speak with your pharmacist.
  • Inform your doctor and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products that you are now taking or intend to use. Include any of the following: levetiracetam (Elepsia, Keppra, Spritam), phenytoin (Dilantin, Phenytek), and rifampin (Carbatrol, Epitol, Equetro, Tegretol, Teril) (Rifadin, Rimactane). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • Inform your doctor if you use or have ever used excessive amounts of street drugs, alcohol, or prescription medications. Tell your doctor if you have or have ever had liver illness, kidney disease, depression, mood disorders, suicidal thoughts or actions, or liver disease. Dialysis is a procedure used to clean the blood outside the body when the kidneys are not functioning properly.
  • Inform your physician if you are nursing a baby, intend to get pregnant, or are already pregnant. Call your doctor if you become pregnant while taking brivaracetam.
  • You should be aware that brivaracetam may cause drowsiness or euphoria, as well as impaired vision, balance issues, or dizziness. Until you are certain of how this drug affects you, avoid operating machinery, driving a car, or engaging in other tasks that call for attentiveness or coordination.
  • Inquire with your doctor if drinking alcohol is safe for you to do while taking brivaracetam. Brivaracetam can exacerbate the negative effects of alcohol.
  • You should be aware that while using brivaracetam, your mental health may alter in unexpected ways and you could develop suicidal thoughts (plans or attempts to hurt or kill yourself). In clinical studies, a small proportion of patients using anticonvulsants like brivaracetam to address a variety of conditions about 1 in 500 adults and children aged 5 and older became suicidal while receiving medication. Some of these individuals started exhibiting suicidal thoughts and actions as little as one week after beginning the medicine. If you take an anticonvulsant drug like brivaracetam, there is a chance that your mental health will change, but there is also a chance that if your disease is untreated, your mental health will change. Whether the hazards of using an anticonvulsant drug outweigh the dangers of not using it will be decided by you and your doctor. Any of the following symptoms should prompt you, your family, or your carer to call your doctor immediately away: panic attacks, agitation or restlessness, fresh occurrences of, or worsening of, irritability, anxiety, or depression, acting on risky impulses, sleep difficulties, aggressive, angry, or violent behaviour, mania (frenzied, abnormally excited mood), talking or thinking about wanting to harm yourself or end your life, or any other unusual changes in behaviour or mood. Make sure your family or carer is aware of any symptoms that could be significant so they can contact the doctor on your behalf if you are unable to call for help.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Brivaracetam might have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Constipation
  • Nausea
  • Vomiting
  • Severe fatigue or lack of vigour

Some adverse effects can be very harmful. You should stop taking brivaracetam and call your doctor right away, or seek emergency medical attention, if you encounter any of these signs or any of the ones mentioned in the SPECIAL PRECAUTIONS section:

  • Face, throat, tongue, lips, and eye swelling
  • Breathing or swallowing challenges
  • Hoarseness
  • Hallucinations (seeing things or hearing sounds and voices that do not exist)
  • Delusions (having weird ideas or convictions that are unfounded in reality), such as the conviction that someone is attempting to harm you when they are not

Other negative effects of brivaracetam are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Store it away from excessive heat and moisture at room temperature (not in the bathroom). After 5 months from the time the bottle was originally opened, discard any leftover oral solution. Keep the oral solution from freezing.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning. http://www.upandaway.org

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at http://goo.gl/c4Rm4p for additional information.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Overdose signs could include the following:

  • Sleepiness
  • Extreme fatigue
  • Dizziness
  • Difficulty maintaining balance
  • Double or blurry vision
  • Reduced heart rate
  • Nausea
  • Feeling uneasy

What other information should I know?

No one else should take your medication. The drug brivaracetam is under control. Only a limited amount of refills are permitted for prescriptions; if you have any doubts, speak with your pharmacist.

Keep all of your doctor’s appointments.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Briviact®
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