WARNING

Biktarvy is a medication used for the treatment of HIV-1 infection in adults. While it’s generally effective and well-tolerated, like any medication, it carries some risks. Common side effects include nausea, diarrhea, headache, and fatigue. More serious but less common side effects may include liver problems, lactic acidosis (a buildup of lactic acid in the blood), and immune reconstitution syndrome (a condition where the immune system reacts to previously hidden infections as it strengthens). Additionally, there may be risks associated with drug interactions, especially with other medications that affect liver enzymes or kidney function. It’s essential for individuals taking Biktarvy to discuss any concerns or potential side effects with their healthcare provider.

Why is this medication prescribed?

Biktarvy is prescribed for the treatment of HIV-1 infection in adults. It is a combination medication containing three different drugs: bictegravir, emtricitabine, and tenofovir alafenamide. These drugs work together to reduce the amount of HIV in the body, helping to control the infection and improve immune function.

How should this medicine be used?

Biktarvy is typically taken orally once a day, with or without food. It’s important to take it exactly as prescribed by your healthcare provider. Here are some general guidelines on how Biktarvy should be used:

• Dosage: The recommended dosage of Biktarvy is one tablet (bictegravir 50 mg/emtricitabine 200 mg/tenofovir alafenamide 25 mg) taken once daily.
• Administration: Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet before swallowing.
• Timing: You can take Biktarvy with or without food. Choose a time of day that works best for you and try to take it around the same time every day to help establish a routine and improve adherence.
• Follow Healthcare Provider’s Instructions: Follow your healthcare provider’s instructions regarding the use of Biktarvy, including any specific recommendations or precautions based on your individual health status.
• Missed Dose: If you forget to take a dose of Biktarvy, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and take your next dose at the regular time. Do not double the dose to make up for a missed one.
• Continued Use: It’s important to continue taking Biktarvy even if you feel well. Do not stop taking it without consulting your healthcare provider, as stopping treatment can allow the HIV virus to become active again and may lead to complications.
• Storage: Store Biktarvy at room temperature away from moisture and heat. Keep it in its original container, tightly closed, and out of reach of children and pets.
• Follow-up: Attend all follow-up appointments with your healthcare provider as scheduled. These appointments are essential for monitoring your response to treatment, assessing any side effects, and making any necessary adjustments to your treatment plan.

If you have any questions or concerns about how to use Biktarvy, be sure to discuss them with your healthcare provider or pharmacist. They can provide personalized guidance and support to ensure that you are using Biktarvy safely and effectively.

Other uses for this medicine

Biktarvy is primarily used for the treatment of HIV-1 infection in adults and is not typically prescribed for other purposes. It’s important to use Biktarvy only as directed by your healthcare provider.

What special precautions should I follow?

Special precautions to follow while taking Biktarvy include:

• Medical History: Inform your healthcare provider about your medical history, including any past or current health conditions, especially kidney problems, liver problems, or bone issues like osteoporosis.
• Pregnancy and Breastfeeding: If you are pregnant or breastfeeding, discuss the risks and benefits of Biktarvy with your healthcare provider. Some HIV medications can be used during pregnancy, but it’s crucial to follow your healthcare provider’s recommendations to minimize the risk of transmission to your baby.
• Drug Interactions: Biktarvy can interact with other medications, including over-the-counter drugs and supplements. Inform your healthcare provider about all the medications and supplements you are taking to avoid potentially harmful interactions.
• Kidney Function Monitoring: Biktarvy contains tenofovir alafenamide, which can affect kidney function. Your healthcare provider will monitor your kidney function regularly while you are taking Biktarvy.
• Bone Density Monitoring: Some HIV medications, including tenofovir alafenamide in Biktarvy, may affect bone density. Your healthcare provider may recommend bone density monitoring or supplements to support bone health.
• Adherence to Treatment: It’s essential to take Biktarvy exactly as prescribed by your healthcare provider. Missing doses or not following the prescribed regimen could reduce its effectiveness and increase the risk of developing drug resistance.
• Side Effects: Be aware of potential side effects of Biktarvy, such as nausea, diarrhea, headache, and fatigue. Contact your healthcare provider if you experience any concerning side effects while taking Biktarvy.

Always consult with your healthcare provider for personalized advice and guidance regarding the use of Biktarvy and any other medications.

What special dietary instructions should I follow?

Regarding special dietary instructions, Biktarvy can generally be taken with or without food. However, if you experience gastrointestinal upset, taking it with food may help alleviate symptoms. There are no specific dietary restrictions associated with Biktarvy, but maintaining a balanced diet and staying hydrated can support overall health.

What should I do if I forget a dose?

If you forget a dose of Biktarvy, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not double the dose to catch up. If you have questions or concerns about missed doses, contact your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Biktarvy is generally well-tolerated, but like any medication, it can cause side effects in some people. Common side effects of Biktarvy may include:

• Nausea
• Diarrhea
• Headache
• Fatigue
• Dizziness
• Insomnia
• Rash

These side effects are usually mild and temporary, resolving on their own as your body adjusts to the medication. However, if any of these side effects persist or worsen, it’s essential to inform your healthcare provider.

In some cases, Biktarvy may cause more serious side effects, although these are less common. These can include:

• Liver problems: Symptoms may include yellowing of the skin or eyes (jaundice), dark urine, abdominal pain, or unexplained fatigue.
• Kidney problems: Signs of kidney problems may include changes in urination, swelling in your ankles or feet, or persistent fatigue.
• Lactic acidosis: This is a rare but serious condition characterized by the buildup of lactic acid in the blood, leading to symptoms such as weakness, muscle pain, difficulty breathing, and abdominal discomfort.
• Immune reconstitution syndrome: This can occur when the immune system begins to recover after starting HIV treatment, leading to inflammation and symptoms related to previously hidden infections.

If you experience any serious side effects while taking Biktarvy, it’s crucial to seek medical attention immediately. Additionally, be sure to inform your healthcare provider of any side effects you experience, even if they seem mild, as they can provide guidance and support to manage them effectively.

What should I know about storage and disposal of this medication?

When it comes to the storage and disposal of Biktarvy:

• Storage: Store Biktarvy at room temperature away from moisture and heat. Keep it in its original container, tightly closed, and out of reach of children and pets. Avoid storing Biktarvy in the bathroom or other humid areas.
• Disposal: Dispose of unused or expired Biktarvy properly according to local regulations or guidelines. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Consult with your pharmacist or healthcare provider for proper disposal methods.

In case of emergency/overdose

• Seek Immediate Medical Attention: If you suspect an overdose or experience severe symptoms such as trouble breathing, loss of consciousness, or severe dizziness, seek emergency medical attention immediately. Call your local emergency services or go to the nearest emergency room.
• Poison Control: You can also contact your local poison control center for guidance on what to do in case of overdose. Keep the medication container with you so you can provide accurate information about the medication ingested.

What other information should I know?

• Regular Monitoring: Your healthcare provider will likely schedule regular check-ups and laboratory tests to monitor your response to Biktarvy treatment, including monitoring for side effects and assessing the effectiveness of the medication in controlling HIV.
• Avoiding Transmission: While Biktarvy can help control HIV, it is not a cure, and you can still transmit the virus to others through unprotected sexual activity or sharing needles. Practice safe sex and use barrier methods like condoms consistently to reduce the risk of transmission.
• Follow-up Care: Attend all follow-up appointments with your healthcare provider as scheduled. These appointments are essential for monitoring your progress, adjusting your treatment plan if necessary, and addressing any concerns or questions you may have.
• Patient Assistance Programs: If you have difficulty affording Biktarvy or if your insurance does not cover it, you may be eligible for patient assistance programs offered by the manufacturer or other organizations. Your healthcare provider or pharmacist can provide information on how to access these programs.
• Medication Adherence: Take Biktarvy exactly as prescribed by your healthcare provider, even if you feel well. Skipping doses or not following the prescribed regimen can reduce the effectiveness of the medication and increase the risk of developing drug resistance.

Always consult with your healthcare provider or pharmacist if you have any questions or concerns about Biktarvy or its use. They can provide personalized guidance and support based on your individual needs and circumstances.