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BiCNU (Generic Carmustine)

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WARNING

Your bone marrow’s ability to produce blood cells may suffer significantly if you take carmustine. This makes it more likely that you’ll experience major bleeding or infection. Call your doctor right away if you have any of the following symptoms: Bloody vomit; vomited material that resembles coffee grounds; unusual bleeding or bruises; black and tarry stools; sore throat; chills; or other indications of infection.

Lung damage from carmustine might occur even years after treatment. Particularly in individuals who received carmustine treatment as children, the lung damage can result in mortality. If you have lung disease now or ever had it, let your doctor know.

Keep all of your appointments with your physician and the lab. To monitor your body’s reaction to carmustine, your doctor may request a few tests.

Why is this medication prescribed?

For some forms of brain tumours, carmustine injection is used. Prednisone and carmustine injection are both used to treat multiple myeloma (a type of cancer of the bone marrow). Along with other drugs, it is also used to treat Hodgkin’s lymphoma (Hodkin’s disease) and non-lymphoma Hodgkin’s (cancer that starts in immune system cells), which have not improved or gotten worse despite being treated with other drugs. Alkylating agents, which include carmustine, are a group of drugs. It operates by reducing or preventing the growth of cancer cells within your body.

How should this medicine be used?

A doctor or nurse will administer the carmustine injection intravenously (into a vein) over the course of at least two hours in a doctor’s office or hospital outpatient clinic. The drug is available as a powder to be mixed with fluid. Typically, it is injected once every six weeks. Every 6 weeks, it can also be given in lesser dosages once day for two consecutive days.

If you encounter certain adverse effects, your doctor may decide to postpone your treatment or change your dose. It is crucial that you communicate your feelings to your doctor throughout your carmustine treatment.

For a copy of the manufacturer’s information for the patient, ask your pharmacist or doctor.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before receiving carmustine injection,

  • If you have an allergy to carmustine or any of the substances in carmustine injection, let your doctor and pharmacist know right away. Request a list of the components from your pharmacist.
  • Inform your doctor and pharmacist about all prescription and over-the-counter drugs, vitamins, and dietary supplements you are currently taking or intend to take. Mention either of the following: phenytoin and cimetidine (Tagamet) (Dilantin). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects. Tell your doctor about all of the medications you are taking, even any not on this list, as other drugs may also interact with carmustine.
  • If you have kidney or liver problems now or in the past, let your doctor know.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Pregnancy should not occur while a patient is receiving a carmustine injection. Call your doctor if you conceive while taking carmustine. The foetus may suffer from carmustine.

What side effects can this medication cause?

Consequences of carmustine may occur. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Nausea
  • Vomiting
  • Headache
  • Loss of coordination or balance
  • Light skin
  • Fainting
  • Dizziness
  • Rapid or erratic heartbeat
  • Chest pain
  • Skin coloration

Some adverse effects can be very harmful. Call your doctor right away if you have any of these signs or any of those in the IMPORTANT WARNING section:

  • Pain, redness, stinging, or swelling at the injection site
  • Uneasy stomach
  • Excessive fatigue or sluggishness
  • Not enough energy
  • Reduced appetite
  • Stomach ache in the top right corner
  • Eyes or skin that have a yellow tint
  • Less urinations
  • Edoema of the lower legs, ankles, feet, or hands

Other negative effects from carmustine injection are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

Carmustine may make you more likely to get other malignancies. Discuss the potential risks of obtaining an injection of carmustine with your doctor.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • BiCNU®
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