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Bevespi Aerosphere (Generic Glycopyrrolate Oral Inhalation)

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Why is this medication prescribed?

Patients with chronic obstructive pulmonary disease can reduce their wheezing, shortness of breath, coughing, and chest tightness using glycopyrrolate oral inhalation (COPD; a group of diseases that affect the lungs and airways, that includes chronic bronchitis and emphysema). Glycopyrrolate belongs to the group of drugs known as anticholinergics. It facilitates breathing by loosening the muscles that surround your lungs’ airways.

How should this medicine be used?

Glycopyrrolate oral inhalation is available as a solution (liquid) to be inhaled by mouth using a specific nebulizer and as a powder-filled capsule to be inhaled by mouth using a special inhaler (machine that turns medication into a mist that can be inhaled). Usually, two times a day, one in the morning and one in the evening, it is breathed. Glycopyrrolate should be inhaled at roughly the same times each day. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Glycopyrrolate should only be used as directed. Never take it in larger or less amounts or more frequently than advised by your doctor.

Gylcopyrrolate capsules and nebulizer solutions should not be consumed.

During a rapid COPD attack, avoid using oral inhalation of glycopyrrolate. To use during COPD attacks, your doctor will prescribe a short-acting (rescue) inhaler.

If your breathing issues worsen, if you need to use your short-acting inhaler more frequently to treat COPD attacks, or if your short-acting inhaler does not improve your symptoms, call your doctor or seek emergency medical attention.

The oral inhalation of glycopyrrolate manages COPD but does not cure it. Glycopyrrolate should still be taken even if you feel OK. Without consulting your doctor, never discontinue taking glycopyrrolate. Your symptoms may worsen if you stop using glycopyrrolate inhalation.

Read the printed directions that come with the inhaler or nebulizer before using glycopyrrolate oral inhalation for the first time. To learn how to put the inhaler or nebulizer together and use it, ask your physician, pharmacist, or respiratory therapist. While he or she observes, practise using the nebulizer or inhaler.

Never inhale any other medications using an inhaler or nebulizer.

For a copy of the manufacturer’s information for the patient, ask your pharmacist or doctor.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before using glycopyrrolate,

  • If you have any allergies, including to any of the substances in the glycopyrrolate powder capsule or nebulizer solution, notify your doctor and pharmacist right away. If you want to use the powder capsule, let your doctor know if you have a lactose allergy (milk proteins). Request a list of the components from your pharmacist.
  • Inform your doctor and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products that you are now taking or intend to use. Incorporate any of the following: aclidinium (Tudorza Pressair), ipratropium (Atrovent HFA, in Combivent Respimat), tiotropium (Spiriva, in Stioloto Respimat), and umeclidinium (Incruse Ellipta, in Anoro Ellipta, Trelegy Ellipta) are other COPD drugs; atropine (in Lomotil, Motofen); antihistamines; oral glycopyrrolate (Cuvposa, Robinul); drugs for ulcers, irritable bowel syndrome, Parkinson’s disease, motion sickness, or urinary issues. Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects. Glycopyrrolate may also interact with a variety of other drugs, so be sure to let your doctor know about all the drugs you’re taking, even if they don’t appear on this list.
  • Inform your doctor if you have or have ever had kidney disease, urinary retention (the inability to completely or completely empty your bladder), prostate problems, or bladder or bladder problems.
  • Inform your physician if you are nursing a baby, intend to become pregnant, or are already pregnant. Call your doctor if you become pregnant while taking glycopyrrolate.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What should I do if I forget a dose?

Ignore the missed dose and carry on with my normal dosing routine. Never take a double dose to catch up on a missed dose or take the medication more than twice daily.

What side effects can this medication cause?

Side effects from oral glycopyrrolate inhalation are possible. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Diarrhea
  • Nausea
  • Stomach ache
  • Joint or back discomfort
  • Headache
  • Extreme exhaustion
  • Arms or legs swelling
  • Throat pain

Some negative effects may be quite detrimental. If you experience any of the following signs, stop using glycopyrrolate oral inhalation and get medical help right away:

  • Sudden breathing difficulties right after use
  • Rash, hives, breathing issues, hoarseness, swelling of the face, throat, tongue, lips, and eyes
  • Nausea, vomiting, and eye pain. visional haziness, the perception of coloured pictures or bright circles around light
  • Urination that is challenging, frequent, painful, or weak

Other negative effects from oral inhalation of glycopyrrolate are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep the nebulizer solution and powder capsules in their original blister packs or foil pouches, unopened, and out of children’s reach. Store it away from excessive heat and moisture at room temperature (not in the bathroom). If glycopyrrolate vials are not used within 7 days of the foil bag being opened, discard them.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at for additional information.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Overdose signs could include the following:

  • Nausea
  • Vomiting
  • Experiencing fainting or dizziness
  • Vision blurriness or other issues with vision
  • Inflamed or painful eyes
  • Constipation
  • Having trouble urinating

What other information should I know?

Do not miss any of your doctor’s appointments.

Never allow someone else to use your medication. If you have any queries regarding getting a prescription renewed, ask your pharmacist.

You should keep a written record of every drug you take, including prescription and nonprescription (over-the-counter) medications, vitamins, minerals, and other dietary supplements. Every time you see a doctor or are admitted to the hospital, you should carry this list with you. Additionally, it is crucial to have this knowledge on hand in case of emergency.

Brand names

  • Lonhala Magnair®
  • Seebri®
  • Bevespi Aerosphere®(as a combination product containing Glycopyrrolate, Formoterol)®
  • Utibron®(as a combination product containing Glycopyrrolate, Indacterol Maleate)®
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