To treat and prevent some bacterial infections, penicillin G injection is utilised. A group of medicines known as penicillins includes penicillin G injection. It functions by eradicating the infection-causing germs.

Colds, the flu, and other viral diseases cannot be treated with antibiotics such as penicillin G injection. Antibiotic use that is not necessary raises the likelihood of developing a later infection that is resistant to antibiotic treatment.

Both a powder to be mixed with water and a premixed product are available for penicillin G injection. Penicillin G injection is typically administered via injection into a muscle or vein, but it can also be administered directly into the fluid surrounding the spinal cord, the lining of the chest cavity, a joint, or other locations. Your general health, the type of infection you have, and how well you respond to the medication will all influence how many doses you will take daily and how long it will take you to complete your course of treatment.

You can either administer penicillin G injection at home or get it in a hospital. If you will be taking penicillin G injection at home, your doctor will instruct you on how to administer the drug. Make sure you comprehend these instructions, and if you have any issues, consult your healthcare professional.

During the initial days of treatment with penicillin G injection, you should start to feel better. Call your doctor if your symptoms don’t go away or get worse.

Even if you feel better, continue to take penicillin G injectable for as long as your doctor instructs you to. Your illness might not be entirely treated if you stop using penicillin G injection too soon or skip doses, and the bacteria might develop an antibiotic resistance.

You may experience a reaction starting one or two hours after receiving your first dose of this medication and lasting for 12 to 24 hours if you are using penicillin G injection to treat certain infections such as syphilis (a sexually transmitted disease), Lyme disease (a disease spread by tick bites that may cause issues with the heart, joints, and nervous system), or relapsing fever (a disease spread by tick bites that causes repeated episodes of fever). Any of the following symptoms, including fever, chills, muscle aches, headache, worsening of skin sores, rapid heartbeat, rapid breathing, and flushing, should be reported to your doctor.

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

Before receiving penicillin G injection,

• Inform your doctor and pharmacist if you have any allergies to penicillin G injection, penicillin antibiotics, cephalosporin antibiotics like cefaclor, cefadroxil, cefazolin (Ancef, Kefzol), cefditoren (Spectracef), cefepime (Maxipime), cefixime (Suprax), cefotaxime (Claforan), cefoxitin, cefpodoxime, cefpro If you are unsure whether a drug you are allergic to falls under one of these categories, consult your doctor or pharmacist. If you have a reaction to any of the components in penicillin G injection, let your doctor know right away. Request a list of the components from your pharmacist.
• Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are currently taking or intend to take. Mention any of the following: erythromycin (Ery-tab, E.E.S., others); aspirin; chloramphenicol; diuretics (‘water pills’) such ethacrynic acid (Edecrin) and furosemide (Lasix); indomethacin (Indocin, Tivorbex); probenecid (Probalan); sulfa antibiotics; and tetracycline (Achromycin). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
• Inform your doctor if you have or have ever had asthma, allergies, hay fever, hives, heart failure, kidney disease, or liver disease. Also let them know if you follow a low sodium or potassium diet.
• Inform your physician if you are nursing a baby, intend to get pregnant, or are already pregnant. Call your doctor if you conceive while receiving an injection of penicillin G.

Keep eating normally unless your doctor instructs you otherwise.

The missed dose should be taken as soon as you remember. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

The injection of penicillin G could have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

• Nausea
• Vomiting
• Where the drug was injected, there may be discomfort, edoema, or redness

Some adverse effects can be very harmful. Stop using penicillin G injection right away, call your doctor right away, or seek emergency medical attention if you experience any of the following symptoms:

• Rash
• Hives
• Itching
• Breathing or swallowing challenges
• Edoema of the hands, feet, ankles, lower legs, cheeks, neck, tongue, lips, and eyes
• Hoarseness
• Fever
• Joint or muscle pain
• Abdominal pain
• Severe diarrhoea (watery or bloody stools) that may persist for up to 2 months or longer after your treatment, along with fever and stomach cramps.
• Uncommon bruising or bleeding
• Urine with blood in it
• Seizures
• Weakness
• Irregular, rapid, or sluggish heartbeat
• Fever, chills, sore throat, or other signs of infection returning

Other side effects from penicillin G injection are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Overdose signs could include the following:

• Agitation
• Confusion
• Jerking actions
• Seeing or hearing things or voices that are not there
• Seizures
• Coma
• Weakness
• Irregular, quick, or sluggish heartbeat

Keep all of your appointments with your physician and the lab. To monitor your body’s reaction to the injection of penicillin G, your doctor will request a few lab tests.

Inform the lab staff and your doctor that you are receiving a penicillin G injection prior to any laboratory test.

Use Clinistix or TesTape (not Clinitest) to test your urine for sugar if you have diabetes and are taking this medicine.

If you have any inquiries regarding penicillin G injection, ask your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.