Benralizumab injection is used in combination with other medications to treat adults and children 12 years of age and older with uncontrolled asthma who also experience wheezing, breathing difficulties, chest tightness, and coughing. The drug benralizumab injection belongs to the monoclonal antibody drug class. It functions by lowering a certain type of white blood cell to aid in reducing edoema and irritability of the airways to make breathing easier.

Benralizumab injection is available as a solution to inject into your upper arm, thigh, or abdomen subcutaneously (just under the skin). In a medical office or healthcare facility, a doctor or nurse often administers it. For the first three doses, it is typically administered once every 4 weeks, and after that, once every 8 weeks. Depending on your illness and how well you respond to the drug, your doctor will decide how long your therapy should last.

If your doctor has prescribed another medicine for you, do not stop taking it or reduce the dosage unless specifically instructed to do so. Your other medications’ dosages might need to be gradually reduced by your doctor.

The injection of benralizumab is not utilised to treat an asthma attack that comes on suddenly. To use during attacks, your doctor will prescribe a short-acting inhaler. Consult your doctor for advice on how to handle sudden asthma attack symptoms. Talk to your doctor if your asthma symptoms worsen or if you experience episodes more frequently.

For a copy of the manufacturer’s information for the patient, ask your pharmacist or doctor.

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

Before receiving benralizumab injection,

• If you have an allergy to benralizumab, any other drugs, or any of the ingredients in benralizumab injection, let your doctor and pharmacist know right once. You can examine the patient information provided by the manufacturer or ask your pharmacist for a list of the ingredients.
• Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
• If you have a parasite infection, let your doctor know.
• Inform your physician if you are nursing a baby, intend to get pregnant, or are already pregnant. Call your doctor if you fall pregnant while receiving a benralizumab injectable.

Keep eating normally unless your doctor instructs you otherwise.

The injection of benralizumab may have adverse effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

• Headache
• Unwell throat

Some adverse effects can be very harmful. Call your doctor right away or seek emergency medical attention if you have any of these symptoms or any of those listed in the SPECIAL PRECAUTIONS section:

• Wheezing or breathing issues
• Hives
• Rash
• Hives
• Flushing
• Enlargement of the tongue, face, and mouth
• Dizziness or fainting

Other adverse effects from benralizumab injection are possible. If you have any strange side effects while taking this medicine, call your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Keep all of your doctor’s appointments.

Ask your pharmacist any inquiries you may have regarding the injection of benralizumab.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.