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Aquatensen (Generic Methyclothiazide)

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Why is this medication prescribed?

High blood pressure is treated with methylclothiazide. Methyclothiazide is also used to treat edoema, which is defined as excess fluid retained in bodily tissues and brought on by a variety of medical conditions, such as heart, kidney, and liver disease, as well as edoema brought on by the use of specific drugs, such as oestrogen and corticosteroids. Methyclothiazide belongs to the group of drugs known as diuretics, also known as “water pills”. It functions by causing the kidneys to excrete salt and water from the body through the urine.

Untreated high blood pressure often causes damage to the kidneys, brain, heart, blood vessels, and other organs. Damage to these organs may lead to heart disease, a heart attack, heart failure, a stroke, renal failure, vision loss, and other problems. In addition to taking medication, making your lifestyle will help you control your blood pressure. These changes include giving up smoking, using alcohol sparingly, adhering to a low-fat and salt diet, maintaining a healthy weight, and working out for at least 30 minutes most days.

How should this medicine be used?

Methyclothiazide is available as a tablet to be swallowed. It is often taken in the morning, once daily. Methyclothiazide should be taken at the same time each day. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Methyclothiazide should be taken as prescribed. Never take it in larger or less amounts or more frequently than directed by your doctor.

Methyclothiazide manages edoema and high blood pressure but does not treat them. Even if you feel good, keep taking methyclothiazide. Without consulting your doctor, do not discontinue taking methyclothiazide.

Other uses for this medicine

Methyclothiazide may also be used to avoid kidney stones in patients with high blood calcium levels, treat patients with diabetes insipidus, treat some electrolyte imbalances, and treat patients with diabetes insipidus. Discuss the potential dangers of using this medication for your illness with your doctor.

Ask your doctor or pharmacist for more details if you’re interested in using this medication for any other conditions.

What special precautions should I follow?

Before taking methyclothiazide,

  • If you have an allergy to methyclothiazide, sulfonamide drugs, any other drugs, or any of the substances in methyclothiazide tablets, let your doctor and pharmacist know right away. For a list of the ingredients, consult the patient information or speak with your pharmacist.
  • Inform your doctor and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products that you are now taking or intend to use. Incorporate any of the following: barbiturates such phenobarbital and secobarbital (Seconal); corticosteroids like fludrocortisone, betamethasone (Decadron, Dexpak, and other brands), budesonide (Entocort), cortisone (Cortone), and others (Florinef), prednisone (Rayos), hydrocortisone (Cortef, Hydrocortone), methylprednisolone (Medrol, Meprolone, others), corticotropin (ACTH, H.P., Acthar Gel), digoxin (Lanoxin), lithium (Lithobid), medications for high blood pressure, and nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (Advil, Motrin, others) (Aleve, Naprosyn, others). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • In case you have kidney illness, let your doctor know. Your doctor could advise against taking methyclothiazide.
  • Asthma, diabetes, gout, excessive cholesterol, systemic lupus erythematosus (SLE), a chronic inflammatory illness, and liver disease should all be disclosed to your doctor.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor right away if you get pregnant while taking methyclothiazide.
  • Make a plan to limit your time spent in the sun and to use sunscreen, sunglasses, and protective clothes. Methyclothiazide may increase the sensitivity of your skin to sunlight.
  • You should be aware that methylclothiazide can make you feel faint, lightheaded, and dizzy if you stand up suddenly from a reclining position. When you initially start taking methyclothiazide, this is more typical. Get out of bed gradually, resting your feet on the floor for a few minutes before standing up, to avoid this issue. These negative effects may be exacerbated by alcohol.

What special dietary instructions should I follow?

Follow these guidelines carefully if your doctor advises you to eat or drink more potassium-rich foods (such as bananas, prunes, raisins, and orange juice) or to follow a low-salt or low-sodium diet.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. If your next dose is approaching, skip the missed one and carry on with your regular dosing regimen. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Often urinating
  • Abdominal pain
  • Uneasy stomach
  • Constipation
  • Diarrhea
  • Reduced appetite
  • Headache
  • Distorted vision

Some adverse effects can be very harmful. Call your doctor right away if you experience any of these symptoms, or go to the hospital for emergency care:

  • Dry lips, thirst, nausea, vomiting, fatigue, restlessness, confusion, muscle weakness, soreness, or cramps, a rapid heartbeat, and other symptoms of electrolyte imbalance and dehydration
  • Eyes and skin that have become yellow
  • Fever
  • Peeling or blistering skin
  • Breathing or swallowing problems
  • Rash
  • Itching
  • Hives

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Store it away from excessive heat and moisture at room temperature (not in the bathroom).

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at for additional information.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your appointments with your physician and the lab. Blood tests should be performed occasionally, and your blood pressure should be checked often.

Inform your doctor and the lab staff that you are taking methyclothiazide prior to any laboratory test.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Aquatensen®
  • Enduron®
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