Nonsteroidal anti-inflammatory drug (NSAID) users, including those who take flurbiprofen, may be at an increased risk of having a heart attack or stroke compared to those who do not use these drugs. These occurrences could be fatal and could occur suddenly. For those who take NSAIDs for an extended period of time, this risk may be larger. If you have recently experienced a heart attack, avoid taking an NSAID like flurbiprofen unless your doctor specifically instructs you to. If you smoke, have or have ever had high cholesterol, high blood pressure, or diabetes, or if you or a family member has ever experienced any of these conditions, let your doctor know. If you suffer any of the following symptoms, get immediate emergency medical attention: slurred speech, shortness of breath, weakness in one side or area of the body, or chest pain.

You shouldn’t take flurbiprofen just before or just after having coronary artery bypass graft surgery (CABG; a form of cardiac surgery).

NSAIDs, including flurbiprofen, can result in stomach or intestine ulcers, bleeding, or holes. These issues can arise at any point during therapy, without any prior symptoms, and they have the potential to be fatal. Long-term NSAID users, the elderly, those in poor health, and those who consume substantial amounts of alcohol while taking flurbiprofen may be at higher risk. If you use any of the following medications, let your doctor know: Aspirin, other NSAIDs including ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), and warfarin (Coumadin, Jantoven) are anticoagulants (also known as “blood thinners”); oral steroids like dexamethasone, methylprednisolone (Medrol), and prednisone (Rayos); and aspirin. Selective serotonin reuptake inhibitors (SSRIs) include citalopram (Celexa), fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), and sertraline (Zoloft), as well as serotonin norepinephrine reuptake inhibitor (Effexor XR). Additionally, let your doctor know if you now have or have ever had stomach or intestinal bleeding, ulcers, or any other bleeding diseases. Call your doctor and stop taking flurbiprofen if any of the following symptoms appear: stomach pain, heartburn, bloody or coffee-ground-looking vomit, blood in the stool, or dark, tarry stools.

Keep all of your appointments with your physician and the lab. Your doctor will closely monitor your symptoms and probably request a few tests to determine how flurbiprofen is affecting your body. Inform your physician about your feelings so that they can prescribe the ideal dosage of medication to cure your problem with the least chance of negative side effects.

The manufacturer’s patient information sheet (Medication Guide) will be sent to you by your doctor or pharmacist when you start taking flurbiprofen and at each time your prescription is renewed. If you have any questions, carefully read the material and contact your doctor or pharmacist. To obtain the Medication Guide, you can also go to the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs) or the manufacturer’s website.

Flurbiprofen is used to treat osteoarthritis (arthritis brought on by a breakdown of the lining of the joints) and rheumatoid arthritis pain, soreness, edoema, and stiffness (arthritis caused by swelling of the lining of the joints). Flurbiprofen belongs to the group of drugs known as NSAIDs. It functions by halting the body’s production of a chemical responsible for inflammation, fever, and discomfort.

Flurbiprofen is available as an oral tablet. Typically, it is consumed two to four times a day. Flurbiprofen should be taken every day at roughly the same time. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Flurbiprofen should be taken as prescribed. Never take it in larger or less amounts or more frequently than directed by your doctor.

Additionally, ankylosing spondylitis is treated with flurbiprofen (arthritis that mainly affects the spine).

Ask your doctor or pharmacist for more details if you’re interested in using this drug for any other conditions.

Before taking flurbiprofen,

• Inform your doctor and pharmacist if you have any allergies to any drugs, including aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), or any of the ingredients in flurbiprofen tablets. For a list of the ingredients, ask your doctor or pharmacist.
• Inform your doctor and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products that you are now taking or intend to use. Mention the drugs in the IMPORTANT WARNING section as well as any of the following: Benazepril (Lotensin, in Lotrel), captopril, enalapril (Vasotec, in Vaseretic), fosinopril, and lisinopril are examples of angiotensin-converting enzyme (ACE) inhibitors (in Zestoretic), Moexipril (Univasc), perindopril (Aceon, in Prestalia), quinapril (Accupril, in Quinaretic), ramipril (Altace), and trandolapril (Mavik, in Tarka); angiotensin receptor blockers (ARBs) such azilsartan (Edarbi, in Edarbyclor), candesartan; and others (Atacand, in Atacand HCT), Losartan (Cozaar, Hyzaar), olmesartan (Benicar, in Azor, in Benicar HCT, in Tribenzor), telmisartan (Micardis, in Micardis HCT, in Twynsta), and valsartan (in Exforge HCT); eprosartan (Teveten), irbesartan (Avapro, in Avalide), valsartan (in Exforge HCT); Atenolol (Tenormin, Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, in Dutoprol), nadolol (Corgard, in Corzide), and propranolol (Hemangeol, Inderal, and Innopran); diuretics (‘water pills’); lithium (Lithobid); and methotrexate are beta block (Otrexup, Rasuvo, Trexall). Your physician might need to adjust the dosage of your medication or keep a closer eye on you for adverse effects.
• Inform your physician if you now have or have ever had asthma, particularly if you also frequently have a stuffy or runny nose, nasal polyps (swelling of the nasal lining), heart failure, swelling in the hands, feet, ankles, or lower legs, or liver or kidney problems.
• Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. If flurbiprofen is consumed after 20 weeks of pregnancy, it may harm the foetus and complicate delivery. Unless specifically instructed to do so by your doctor, avoid taking flurbiprofen during or after the first 20 weeks of pregnancy. Call your doctor if you become pregnant while taking flurbiprofen.
• Inform your doctor or dentist that you are taking flurbiprofen if you are undergoing surgery, including dental surgery.

Keep eating normally unless your doctor instructs you otherwise.

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

Flurbiprofen could have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

• Headache
• Anxiety or jitters
• Depression
• Memory issues
• Shaking of a body part that is out of your control
• Having trouble falling or staying asleep
• Vomiting
• Gas
• Constipation
• Diarrhea
• Clogged nose
• An earache that ringers

Some adverse effects can be very harmful. Call your doctor right away if you have any of the following symptoms or any of those detailed in the IMPORTANT WARNING section. Flurbiprofen should not be taken any longer until you have spoken to your doctor.

• Alterations to vision (blurriness, difficulty seeing)
• Unaccounted-for weight gain
• Respiratory issues or shortness of breath
• Abdomen, ankles, foot, or legs swelling
• Fever
• Blisters
• Rash
• Itching
• Hives
• Eye, face, lip, tongue, throat, or hand swelling
• Breathing or swallowing challenges
• Light skin
• Rapid heart rate
• Excessive fatigue
• Uncommon bruising or bleeding
• Not enough energy
• Nausea
• Reduced appetite
• Upper right stomach region discomfort
• Flu-like signs
• The skin or eyes turning yellow
• Urine that is cloudy, discoloured, or bloody
• Back ache
• Uncomfortable or challenging urinating

Other negative effects of flurbiprofen are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

Keep this medication tightly closed in the original container and out of the reach of children. Store it away from excessive heat and moisture at room temperature (not in the bathroom).

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning. http://www.upandaway.org

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at http://goo.gl/c4Rm4p for additional information.

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Overdose symptoms could include:

• Not enough energy
• Drowsiness
• Nausea
• Vomiting
• Abdominal pain
• Faeces that are red, black, or tarry
• Vomit that is reddish-colored or resembles coffee grounds
• Having trouble breathing
• Coma (loss of consciousness for a period of time)

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.