WARNING

Annovera is a hormonal contraceptive in the form of a vaginal ring, which releases estrogen and progestin. While effective for preventing pregnancy, it comes with some risks and potential side effects, including:

• Blood Clots: Increased risk of deep vein thrombosis and pulmonary embolism.
• Stroke: Slightly elevated risk, especially for those with other risk factors.
• Heart Attack: Risk can be higher in smokers and individuals with cardiovascular disease.
• High Blood Pressure: Can be exacerbated by hormone use.
• Liver Issues: Rare but possible, particularly in those with preexisting liver conditions.
• Breast Cancer: Slight increase in risk, especially with prolonged use.
• Mood Changes: Possible mood swings or depressive symptoms.

It’s important to discuss your medical history and any potential risks with your healthcare provider before starting Annovera.

Why is this medication prescribed?

Annovera is a vaginal contraceptive ring that contains a combination of estrogen and progestin. It is prescribed primarily for:

• Birth Control: It provides effective contraception by preventing ovulation (the release of an egg from the ovary) and thickening cervical mucus to block sperm from entering the uterus.
• Regulation of Menstrual Cycles: It can help regulate menstrual cycles and reduce menstrual cramps.
• Management of Hormonal Imbalances: It may be used to manage symptoms related to hormonal imbalances, such as heavy periods or irregular bleeding.

How should this medicine be used?

Here’s a general guide on how it is typically used:

• Insertion: Place the ring into your vagina. It should be comfortable and positioned high in the vaginal canal. You don’t need to worry about the exact position; it will stay in place naturally.
• Duration: The ring is used for three weeks continuously, during which time it releases hormones to prevent pregnancy.
• Removal and Replacement: After three weeks, remove the ring and have a week-long break. During this break, you will typically have a menstrual-like withdrawal bleed. After the week off, insert a new ring to continue contraception.
• Missed Ring: If the ring is out for more than three hours during the three weeks of use, it may be less effective. Refer to the manufacturer’s instructions or consult your healthcare provider for guidance on what to do if this happens.
• Storage: Keep the ring in its original packaging until you’re ready to use it, and store it in a cool, dry place.

Always follow the specific instructions provided with your Annovera ring and consult with your healthcare provider for personalized advice and to ensure it’s the right method of contraception for you.

Other uses for this medicine

Besides its primary use as a contraceptive, Annovera may also be used for:

• Management of Menstrual Disorders: It can help manage conditions like heavy or irregular menstrual bleeding.
• Relief from Menstrual Cramps: It may reduce menstrual cramps due to the hormonal regulation it provides.
• Hormonal Imbalance: It can help address symptoms associated with hormonal imbalances.

What special precautions should I follow?

When using Annovera, consider the following precautions:

• Medical History: Inform your healthcare provider of any personal or family history of blood clots, stroke, heart disease, high blood pressure, or certain types of cancers, such as breast cancer.
• Smoking: Avoid smoking, especially if you are over 35, as it increases the risk of serious cardiovascular side effects associated with hormonal contraceptives.
• Interactions with Other Medications: Some medications or supplements can reduce the effectiveness of Annovera, such as certain antibiotics and anti-seizure medications. Inform your healthcare provider about all medications you are taking.
• Pregnancy and Breastfeeding: Annovera should not be used during pregnancy. Consult with your healthcare provider if you are breastfeeding, as the safety during lactation should be assessed.
• Vaginal Health: If you experience vaginal infections, unusual discharge, or irritation, consult your healthcare provider. Annovera is intended for vaginal use, so maintaining vaginal health is important.
• Insertion and Removal: Ensure you follow proper insertion and removal instructions. If the ring is displaced or falls out, it might not be effective in preventing pregnancy.
• Regular Check-ups: Regular medical check-ups are recommended to monitor your overall health and any potential side effects related to hormonal contraception.

Always follow your healthcare provider’s guidance and read the patient information leaflet provided with Annovera for detailed instructions and safety information.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Annovera. However, maintaining a balanced diet can contribute to overall health and well-being. If you have any specific dietary concerns or health conditions that might interact with hormonal contraceptives, discuss them with your healthcare provider.

What should I do if I forget a dose?

• Insertion Timing: If you forget to insert a new ring at the beginning of a new cycle or if the ring has been out for more than 3 hours during the 3 weeks of use, follow these steps:
  • If Less Than 7 Day: Insert the ring as soon as you remember. Use additional contraception, such as condoms, until the ring has been in place for 7 consecutive days.
  • If More Than 7 Days: Insert a new ring immediately. You will need to use additional contraception (e.g., condoms) for the first 7 days after insertion.
• Missed Ring: If the ring is out for more than 3 hours, effectiveness may be reduced. Reinsert it as soon as possible and use backup contraception for the next 7 days.

What side effects can this medication cause?

Annovera, like other hormonal contraceptives, can cause various side effects. While not everyone experiences side effects, some common and less common ones include:

Common Side Effects:

• Vaginal Discharge: Some users may notice an increase in vaginal discharge or changes in its consistency.
• Irregular Bleeding: Spotting or breakthrough bleeding can occur, especially during the first few months of use.
• Headaches: Hormonal changes can sometimes lead to headaches or migraines.
• Nausea: Some people may experience nausea, particularly when they first start using Annovera.
• Breast Tenderness: Tender or swollen breasts are common with hormonal contraceptives.
• Mood Changes: Hormonal fluctuations can lead to mood swings or emotional changes.

Less Common or Serious Side Effects

• Blood Clots: Annovera may increase the risk of blood clots, especially if you have other risk factors such as smoking or a history of clotting disorders.
• Stroke or Heart Attack: The risk of cardiovascular issues can be higher in certain individuals, particularly those with underlying health conditions.
• Severe Allergic Reactions: Although rare, some users might experience symptoms of an allergic reaction, such as rash, itching, or swelling.
• Liver Issues: Rarely, hormonal contraceptives can affect liver function or lead to liver tumors.
• High Blood Pressure: Hormonal changes can impact blood pressure.

Always consult your healthcare provider if you have concerns about side effects or if you experience any symptoms that seem unusual or severe. They can provide guidance based on your specific health profile and needs.

What should I know about storage and disposal of this medication?

Storage and Disposal of Annovera:

• Storage:
  • Store Annovera in its original packaging at room temperature, typically between 59°F and 86°F (15°C to 30°C).
  • Keep it away from moisture and direct sunlight.
  • Store it out of the reach of children and pets to prevent accidental ingestion.
• Disposal:
  • Do not flush Annovera down the toilet or pour it down the drain.
  • Follow local guidelines for the disposal of medications. If specific disposal instructions are provided with Annovera, follow them. If no instructions are available, consult your pharmacist for advice on safe disposal methods.

In case of emergency/overdose

• Increased Risk: Overdose of Annovera is unlikely due to its hormonal nature, but taking an excessive amount may potentially cause side effects like nausea, vomiting, or vaginal bleeding.
• Seek Medical Help: If you experience severe symptoms or if you suspect an overdose, contact your healthcare provider or go to the nearest emergency room for evaluation.
• Regular Check-ups: Regular medical check-ups are recommended to ensure the proper use of Annovera and to monitor any side effects or issues.
• Follow Instructions: Always follow the instructions for use and any additional guidance provided by your healthcare provider.

What other information should I know?

• Use Consistency: Ensure that you use Annovera as directed without missing the insertion and removal schedule to maintain its effectiveness.
• Backup Contraception: Use backup contraception, such as condoms, if the ring has been out of place for more than 3 hours or if you missed re-insertion after the break week.
• Consult Your Provider: If you have any questions or concerns about how Annovera affects you, or if you experience any unusual symptoms, consult your healthcare provider for personalized advice.

By following these guidelines, you can ensure that you are using Annovera safely and effectively.