Adults with moderate to severe systemic lupus erythematosus (SLE or lupus; an autoimmune illness in which the immune system targets healthy body parts like joints, skin, blood vessels, and organs) can be treated with anifrolumab in combination with other drugs. The drug anifrolumab injection belongs to the group of drugs known as monoclonal antibodies. It functions by preventing a specific protein in SLE patients from acting.

Anifrolumab is available as a solution (liquid) for intravenous injection (into a vein). Every four weeks, it is typically administered over a 30-minute period. In accordance with how your body reacts to this drug, your doctor will determine how frequently you should take anifrolumab.

Anifrolumab aids in lupus management but does not treat it. To determine how well anifrolumab works for you, your doctor will closely monitor you. It is critical to communicate your feelings to your doctor during your therapy.

For a copy of the manufacturer’s information for the patient, ask your pharmacist or doctor.

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

Before receiving anifrolumab,

• If you have an allergy to anifrolumab, any other drugs, or any of the ingredients in anifrolumab injection, let your doctor and pharmacist know right away. Request a list of the components from your pharmacist.
• Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
• Inform your physician if you have an infection, an infection that returns frequently, or if you currently have or have ever had cancer.
• If you are breastfeeding a child or intend to become pregnant, let your doctor know. Call your doctor if you get pregnant while taking anifrolumab.
• Without consulting your doctor, avoid getting any immunisations while you are receiving therapy.

Keep eating normally unless your doctor instructs you otherwise.

Call your physician as soon as you can if you are unable to keep an appointment to receive anifrolumab.

There may be negative consequences from anifrolumab. If any of these symptoms are severe or do not go away, let your doctor know right once:

• Headache
• Nausea
• Vomiting
• Tiredness

Some adverse effects can be very harmful. Call your doctor right away if you encounter any of these symptoms, or seek emergency care:

• Fever, chills, sore throat, cough, or other infection-related symptoms
• Constipation or diarrhoea
• Urination that is frequent, unpleasant, or challenging
• Body sores or skin that is red or uncomfortable
• Face, tongue, or mouth swelling
• Stumbling or dizziness
• Having trouble breathing

Anifrolumab may make some malignancies more likely for you to develop. You should discuss the dangers of using this drug with your doctor.

Other negative effects of anifrolumab are possible. If you have any strange side effects while taking this medicine, call your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Keep all of your doctor’s appointments.

Ask any queries you may have regarding anifrolumab to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.