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Amiloride

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Why is this medication prescribed?

When treating individuals with high blood pressure and heart failure who have low potassium levels in their bodies or for whom low potassium levels in the body could be harmful, amiloride is typically used with other diuretics (sometimes known as “water pills”). Amiloride belongs to the group of drugs known as diuretics. It functions by encouraging the kidneys to excrete extra water and salt from the body through the urine, while minimising potassium loss.

High blood pressure is a common illness that, if left untreated, can harm the kidneys, brain, heart, blood vessels, and other organs. Heart disease, a heart attack, heart failure, a stroke, renal failure, eyesight loss, and other issues may result from damage to these organs. Making lifestyle modifications will help you control your blood pressure in addition to taking medication. These adjustments include quitting smoking, drinking alcohol in moderation, eating a diet low in fat and salt, keeping a healthy weight, and exercising for at least 30 minutes most days.

How should this medicine be used?

Amiloride is available as an oral tablet. It is typically taken with food once a day. Take amiloride at roughly the same time each day to make it easier for you to remember to take it. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Follow the amiloride directions precisely. Never take it in larger or less amounts or more frequently than directed by your doctor.

Despite not curing heart failure or high blood pressure, this medicine manages their symptoms. Even if you feel good, keep taking amiloride. Without consulting your doctor, do not discontinue taking amiloride.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before taking amiloride,

  • If you have any allergies, whether they be to amiloride, any other medications, or any of the substances in amiloride, tell your doctor and pharmacist. Request an ingredient list from your pharmacist.
  • Inform your doctor if you are taking spironolactone (Aldactone, in Aldactazide), other triamterene-containing medications, potassium supplements, or supplements containing potassium-containing drugs. If you are taking one or more of these drugs, your doctor generally won’t let you take amiloride.
  • Inform your doctor and pharmacist about any additional prescription and non-prescription drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Make sure you bring up any of the following: angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin, in Lotrel), captopril (Capoten), fosinopril, lisinopril (in Prinzide, in Zestoretic), moexipril (Univasc, in Uniretic), perindopril (Aceon), quinapril (Accupril, in Accuretic), ramipri; angiotensin II receptor antagonists (ARB), such as azilsartan (Edarbi, Edarbyclor), candesartan (Atacand, in Teveten HCT), eprosartan (Teveten, in Teveten HCT), irbesartan (Avapro, in Avalide), losartan (Cozaar, in Hyzaar), olmesartan (Benicar, in Azor, Benicar HCT); lithium (Lithobid), cyclosporine (Gengraf, Neoral, Sandimmune), nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (Advil, Motrin, and other brands), indomethacin (Indocin), and naproxen (Aleve, Naprosyn, and other brands), or tacrolimus are examples of these medications (Astagraf XL, Prograf). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • In case you have kidney illness, let your doctor know. Your physician might advise against taking amiloride.
  • If you have diabetes or liver disease, let your doctor know.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. While taking amiloride, call your doctor right away if you become pregnant.

What special dietary instructions should I follow?

While using this medication, stay away from salt alternatives that include potassium. Discuss with your doctor how much potassium-rich food you consume, such as bananas, prunes, raisins, and orange juice.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Amiloride could have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Headache
  • Heartburn
  • Reduced appetite
  • Nausea
  • Diarrhea
  • Vomiting
  • Gas

Some adverse effects can be very harmful. Call your doctor right away if any of these symptoms occur to you:

  • Other symptoms of dehydration and electrolyte imbalance include a dry mouth, thirst, numbness and tingling, confusion, muscle weakness, stomach pain, or cramps, and a rapid heartbeat.
  • Skin or eyes turning yellow
  • Chest pain
  • Rash
  • Itching
  • Hives
  • Breathing or swallowing challenges

Other negative effects of amiloride are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Store it away from excessive heat and moisture at room temperature (not in the bathroom). Avoid freezing.

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at http://goo.gl/c4Rm4p for additional information.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning. http://www.upandaway.org

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your appointments with your physician and the lab. Regular blood pressure checks are necessary to monitor how amiloride affects you. To monitor your body’s reaction to amiloride, your doctor could request specific lab tests.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Midamor®
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