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Albiglutide Injection

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WARNING

Albiglutide injection could make you more likely to develop thyroid malignancies, especially medullary thyroid carcinoma (MTC; a type of thyroid cancer). It is unknown if drugs comparable to albiglutide enhance the risk of cancers in people, however laboratory animals treated with these drugs developed tumours. Tell your doctor if you or anybody in your family has Multiple Endocrine Neoplasia syndrome type 2 (MTC) now or previously had it (MEN 2; condition that causes tumours in more than one gland in the body). If so, your physician will likely advise against using albiglutide injection. Call your doctor right away if you have any of the following symptoms: a neck bulge or enlargement, hoarseness, trouble swallowing, or shortness of breath.

Keep all of your appointments with your physician and the lab. To monitor your body’s reaction to the injection of albiglutide, your doctor might prescribe specific tests.

When you start receiving treatment with albiglutide injection and every time your prescription is renewed, your doctor or pharmacist will provide you the manufacturer’s patient information leaflet (Medication Guide). If you have any questions, carefully read the material and contact your doctor or pharmacist. The Medication Guide is also available on the manufacturer’s website or the Food and Drug Administration (FDA) website.

Discuss the dangers of using albiglutide injection with your doctor.

Why is this medication prescribed?

When other medications did not sufficiently control levels, albiglutide injection is used in combination with a diet and exercise programme to control blood sugar levels in adults with type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood). Albiglutide injection is not used to treat diabetic ketoacidosis or type 1 diabetes, a condition in which the body does not make insulin and cannot regulate the quantity of sugar in the blood (a serious condition that may develop if high blood sugar is not treated). Albiglutide injection belongs to the group of drugs known as incretin mimetics. When blood sugar levels are high, it aids the pancreas in releasing the proper quantity of insulin. Insulin aids in the transfer of blood sugar to different bodily tissues where it is used as an energy source. Albiglutide injection also functions by reducing how quickly food passes through the stomach.

People with diabetes and high blood sugar over time may experience serious or fatal complications, such as heart disease, stroke, kidney issues, nerve damage, and vision issues. It may be possible to control your diabetes and enhance your health by using medication(s), making lifestyle changes (such as diet, exercise, and quitting smoking), and routinely checking your blood sugar. This treatment may also lower your risk of heart attack, stroke, kidney failure, nerve damage (resulting in numb, cold legs or feet and diminished sex capacity in both men and women), eye issues, such as changes in eyesight or blindness, or gum disease, which are all symptoms of diabetes. The optimal strategy to manage your diabetes will be discussed with you by your doctor and other healthcare professionals.

How should this medicine be used?

Albiglutide injection is available as a powder that must be dissolved in water and then injected subcutaneously using a prefilled dosage pen (under the skin). Typically, it is injected once a week, regardless of meals. Use albiglutide injection at any time on the same day each week. As long as it has been four or more days since your last dose of albiglutide, you are free to switch the day of the week on which you take it. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Administer albiglutide injection as prescribed. Use it only as directed by your doctor, neither more nor less often.

The injection of albiglutide manages diabetes but does not cure it. Albiglutide injection should be continued even if you feel OK. Without consulting your doctor, never discontinue using albiglutide injection.

Prefilled dosage pens for albiglutide are available and include enough medicine for one dose. Never combine albiglutide with any other medications; always provide it in its own prefilled dosage pen.

Read the medication’s manufacturer’s directions for use very carefully. These directions explain how to prepare and administer an albiglutide injectable dosage. If you have any concerns about how to prepare or administer this medication, be sure to see your doctor or pharmacist.

Before injecting your albiglutide, always check it. It must be solid-particle-free, transparent, and yellow.

Albiglutide injection sites include the upper arm, thigh, and stomach. Never administer albiglutide into a muscle or vein. With each dose, switch (rotate) the injection location inside the designated area. Albiglutide and insulin can both be injected into the same body part, but you shouldn’t administer them simultaneously.

Never share or reuse pens or needles. For every injection, a fresh needle should be used. Put needles in a container that won’t puncture. For disposal instructions on the puncture-resistant container, consult your doctor or pharmacist.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before using albiglutide injection,

  • If you have an allergy to albiglutide, any other drugs, or any of the ingredients in albiglutide injection, let your doctor and pharmacist know right away. For a list of the ingredients, consult the Medication Guide or speak with your pharmacist.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Because albiglutide may alter how these medications are absorbed by your body, it is crucial that you inform your doctor about all oral medications you take. Include any oral sulfonylureas, such as chlorpropamide (Diabinese), glimepiride (Amaryl, in Avandaryl, in Duetact), glipizide (Glucotrol), glyburide (DiaBeta, Glynase, in Glucovance), tolazamide, and tolbutamide, as well as insulin or other diabetes drugs. Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • Inform your doctor if you have or have had had renal or liver disease, significant stomach issues such as gastroparesis (slow movement of food from the stomach to the small intestine), or problems with digestion.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you get pregnant while taking albiglutide injection.
  • In the event that you become ill, endure extraordinary stress, or acquire an illness or fever, consult your doctor for advice. Your blood sugar and the possible dosage of albiglutide that you require can be impacted by these circumstances.

What special dietary instructions should I follow?

Make sure to abide by all dietary and exercise advice given to you by your physician or nutritionist.

What should I do if I forget a dose?

The missed dose should be taken as soon as you remember. If it has been more than 3 days since the missed dose, skip it and carry on with your regular dosing schedule. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Your blood sugar levels may alter as a result of this drug. You should be aware of the signs of low and high blood sugar as well as what to do if you experience these signs.

Side effects from albiglutide injection could exist. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Diarrhea
  • Nausea
  • Heartburn
  • Rash, redness, or swelling at the injection site
  • Symptoms of the flu or a cough

Some adverse effects can be very harmful. Stop using albiglutide injection right away, call your doctor right away, or seek emergency medical attention if you have any of these signs or any of those in the IMPORTANT WARNING section:

  • Continual stomach ache that starts in the upper left or middle but can sometimes travel to the rear
  • Vomiting
  • Hives
  • Rash
  • Itching
  • Having trouble breathing

Other negative effects from albiglutide injection are possible. If you experience any strange issues while taking this drug, call your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Away from excessive heat and moisture, store it in the refrigerator or at room temperature for up to 4 weeks before using (not in the bathroom). Avoid freezing.

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at http://goo.gl/c4Rm4p for additional information.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning. http://www.upandaway.org

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Overdose symptoms could include:

  • Nausea and vomiting very badly

What other information should I know?

Do not share your medication with anybody else. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Tanzeum®
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