Why is this medication prescribed?

Aggrenox is a medication used to reduce the risk of stroke in patients who have had a previous ischemic stroke or transient ischemic attack (TIA). It combines two drugs: aspirin and dipyridamole. Aspirin helps to prevent blood clots by inhibiting platelet aggregation, while dipyridamole works by improving blood flow and also has antiplatelet effects.

How should this medicine be used?

Here are general guidelines for its use:

• Dosage: The usual dose is one capsule taken twice a day. It’s important to follow your doctor’s instructions regarding the dosage and schedule.
• Administration: Take Aggrenox with or without food. Swallow the capsules whole; do not crush, chew, or dissolve them.
• Consistency: Try to take the medication at the same times each day to help remember your doses.
• Missed Dose: If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose; do not double up to make up for a missed dose.
• Monitoring: Regular check-ups with your healthcare provider are essential to monitor for any potential side effects or complications.

Always consult your healthcare provider for personalized advice and instructions based on your health condition.

Other uses for this medicine

While Aggrenox is primarily prescribed for stroke prevention, in some cases, it might be used off-label to help prevent heart attacks or other cardiovascular events in patients with a high risk of blood clots.

What special precautions should I follow?

Aggrenox is a combination medication that includes aspirin and dipyridamole, used primarily to reduce the risk of stroke in people who have had a transient ischemic attack (TIA) or ischemic stroke. Here are some special precautions to follow:

• Allergies and Sensitivities: Inform your healthcare provider if you have any allergies to aspirin, dipyridamole, or other medications. Also, let them know if you have any history of asthma, nasal polyps, or allergic reactions to aspirin.
• Bleeding Risk: Since Aggrenox contains aspirin, it can increase your risk of bleeding. Avoid taking it with other blood thinners or NSAIDs unless directed by your doctor. Be cautious with activities that could increase your risk of bleeding or bruising.
• Kidney and Liver Function: Inform your doctor if you have kidney or liver problems, as these conditions can affect how your body processes the medication.
• Pregnancy and Breastfeeding: If you are pregnant, plan to become pregnant, or are breastfeeding, discuss this with your healthcare provider. Aggrenox may not be recommended during certain stages of pregnancy or while breastfeeding.
• Surgical or Dental Procedures: Let your surgeon or dentist know you are taking Aggrenox before any planned procedures, as it can affect bleeding and healing.
• Interactions with Other Medications: Provide a complete list of all medications, supplements, and herbal products you are taking, as Aggrenox can interact with other drugs, including blood thinners, certain antidepressants, and other medications.
• Medical Conditions: Inform your doctor about any other medical conditions you have, such as ulcers, gastrointestinal problems, or any bleeding disorders, as these can influence the safety and efficacy of Aggrenox.

Always follow your healthcare provider’s instructions and discuss any concerns or side effects you experience while taking Aggrenox.

What special dietary instructions should I follow?

• Avoid Excessive Alcohol: Limit alcohol consumption as it can increase the risk of bleeding and may interfere with the effectiveness of Aggrenox.
• Maintain a Balanced Diet: No specific dietary restrictions are generally required, but maintaining a balanced diet is always beneficial for overall health.

What should I do if I forget a dose?

• Timing: If you remember within a few hours of your missed dose, take it as soon as possible.
• Next Dose: If it’s almost time for your next dose, skip the missed dose. Do not take two doses at once to make up for a missed dose.
• Consult: Contact your healthcare provider or pharmacist if you’re unsure about what to do or if you miss doses frequently.

What side effects can this medication cause?

Aggrenox can cause a range of side effects, some of which may require medical attention. Common and serious side effects include:

Common Side Effects:

• Headache: Often occurs when starting the medication, usually subsiding with continued use.
• Dizziness or Lightheadedness: Can happen, especially when standing up quickly.
• Stomach Upset: Nausea, abdominal pain, or indigestion.
• Bleeding or Bruising: Mild bleeding, such as nosebleeds or easy bruising, can occur.

Serious Side Effects:

• Severe Bleeding: This can include bleeding in the stomach, intestines, or other parts of the body. Symptoms might include severe abdominal pain, blood in stools or urine, or unusual bleeding.
• Allergic Reactions: Signs include rash, itching, swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.
• Liver Problems: Symptoms might include yellowing of the skin or eyes (jaundice), dark urine, severe stomach/abdominal pain, or unusual fatigue.

Less Common Side Effects:

• Heart Issues: Rarely, Aggrenox might affect heart rhythm or cause chest pain.
• Gastrointestinal Issues: Severe stomach pain, ulcers, or bleeding in the digestive tract.

If you experience any severe or unusual symptoms, it’s important to seek medical attention promptly. For ongoing side effects or concerns, consult your healthcare provider for advice and possible adjustments to your treatment.

What should I know about storage and disposal of this medication?

Storage and disposal of Aggrenox:

• Storage: Keep Aggrenox at room temperature, away from moisture and heat. Store it in a tightly closed container, away from direct light.
• Disposal: Do not flush Aggrenox down the toilet or pour it into a drain unless instructed to do so. Dispose of unused or expired medication according to your local pharmacy’s take-back program or guidelines. Many pharmacies offer medication disposal services.

In case of emergency/overdose

• Symptoms of Overdose: Symptoms may include severe bleeding (such as blood in the urine or stools), dizziness, or unusual bruising.
• What to Do: If you suspect an overdose, contact emergency medical services or go to the nearest emergency room immediately. You can also call your local poison control center for guidance.

What other information should I know?

• Regular Monitoring: Regular check-ups with your healthcare provider are important to monitor the medication’s effectiveness and any potential side effects.
• Interaction with Other Medications: Keep your healthcare provider informed about all medications and supplements you are taking, as Aggrenox can interact with other drugs and affect how they work.
• Consistent Use: Take Aggrenox exactly as prescribed. Skipping doses or changing the dose without consulting your healthcare provider can affect the effectiveness of the medication.
• Emergency Information: Always carry an emergency contact card with information about your medications and health conditions.

If you have any additional questions or concerns, discussing them with your healthcare provider is always a good idea. They can provide you with personalized advice and support.