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Aerospan HFA (Generic Flunisolide Oral Inhalation)

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Why is this medication prescribed?

Flunisolide oral inhalation is used to treat asthma in adults and children 6 years of age and older by preventing symptoms like coughing, wheezing, tightness in the chest, and difficulty breathing. It belongs to a group of drugs called corticosteroids. Flunisolide facilitates breathing by reducing inflammation and edoema in the airways.

How should this medicine be used?

Flunisolide is available as an aerosol for oral inhalation. It is typically breathed in twice daily. Flunisolide should ideally be taken every day at roughly the same time. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Follow the flunisolide directions exactly. Use it only as directed by your doctor, neither more nor less often.

While receiving treatment with flunisolide inhalation, discuss with your doctor how you should utilise the other oral and inhaled asthma drugs that you are already taking. Ask your doctor if you should use any other inhaled medications for a specific period of time before and after using flunisolide inhalation if you currently use any other inhaled medications. Your doctor may decide to gradually reduce the dosage of any oral steroids you were taking, such as dexamethasone, methylprednisolone (Medrol), or prednisone (Rayos), starting at least one week after you start using flunisolide inhalation.

Flunisolide inhalation aids in preventing asthma attacks, which are abrupt episodes of wheezing, coughing, and shortness of breath, but it cannot halt an attack that has already begun. Whenever you have an asthma attack, avoid using flunisolide inhalation. To use during asthma attacks, your doctor will prescribe a short-acting inhaler.

Flunisolide inhalation will likely be started for you at a typical dose by your doctor. When your symptoms have been controlled for at least four weeks, your doctor may reduce your dose if they have not improved.

Inhaling flunisolide manages asthma but does not cure it. Before you experience the full benefits of the drug, it could take 2 to 4 weeks or longer. Flunisolide inhalation should be continued even if you feel OK. Stop using flunisolide inhalation only after consulting your physician.

If your asthma gets worse while you’re receiving therapy, tell your doctor. If an asthma attack doesn’t end after you take your fast-acting asthma medicine or if you need to take more of your fast-acting medication than normal, call your doctor.

Depending on its size, a flunisolide aerosol canister is intended to deliver 60 or 120 inhalations. Later inhalations could not contain the prescribed dosage of medication if the labelled number of inhalations has been reached. To determine the precise number of sprays left in your inhaler, you should also keep track of how many inhalations you use each day. Even though the canister still has some liquid and continues to spray when squeezed, you should discard it once you have utilised the indicated number of inhalations. Do not estimate how many sprays are still in your inhaler if it is dropped by the number on the counter.

The written instructions that come with your flunisolide aerosol inhaler should be read before you use it for the first time. Make sure you understand the inhaler’s component parts by carefully studying the diagrams. You can get instructions on how to use it from your physician, pharmacist, or respiratory therapist.

When using your flunisolide inhaler, keep your distance from any heat or open flames. Experiencing really high temperatures could cause the inhaler to blow up.

These instructions should be followed to utilise the aerosol inhaler. Use only one spacer when using the inhaler:

  • A room temperature inhaler must be used.
  • For the first time or if it has been more than 14 days since your last usage, prime the inhaler by releasing two test sprays into the air, away from your face. To avoid getting the medicine in your eyes or face, take caution when spraying it.
  • Grasp the canister with your index finger and place the bottom of the grey spacer on the base of your thumb. A canister should be inserted into the purple actuator; double-check this.
  • Shake the inhaler while maintaining a firm grip on the canister with your thumb and index finger.
  • Use your mouth to take in and let out breaths.
  • Place the mouthpiece in your mouth after exhaling, then seal your lips around it.
  • Take a long, steady breath in through your mouth. At the same time, firmly press down with your index finger on the centre of the dose indicator located at the top of the canister. Immediately after the spray is released, take off your index finger.
  • Remove the inhaler from your mouth and seal your mouth after inhaling deeply for at least three seconds.
  • Try to hold your breath for 10 seconds or so, after which you should breathe normally.
  • Repeat steps 4 through 9 if your doctor has instructed you to inhale more than one puff per session.
  • Put the actuator back in its straight position by pressing it.
  • Spit out the water after rinsing your mouth with it. Don’t ingest the water.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you’re interested in using this drug for any other conditions.

What special precautions should I follow?

Before using flunisolide inhalation,

  • If you have an allergy to flunisolide, any other drugs, or any of the ingredients in flunisolide inhalation, let your doctor and pharmacist know right away. Request a list of the components from your pharmacist.
  • Inform your doctor and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products that you are now taking or intend to use. Incorporate any of the following: Medication for seizures and oral steroids such dexamethasone, methylprednisolone (Medrol), and prednisone (Rayos). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects. Tell your doctor about all of the medications you are taking, including any not on this list, since many other drugs may also interact with flunisolide inhalation.
  • Use of flunisolide during an asthma episode is not advised. To use during asthma attacks, your doctor will prescribe a short-acting inhaler. If an asthma attack persists despite the use of a fast-acting asthma medicine or if you need to use more fast-acting medication than normal, contact your doctor right away.
  • Inform your doctor if you have had prolonged bed rest or immobility as well as if anyone in your family currently has or has previously had osteoporosis (a condition in which the bones become thin and weak and break easily). Inform your doctor if you have cataracts (clouding of the lens of the eye), glaucoma, or TB (a type of lung infection) (an eye disease). Additionally, let your doctor know if you have herpes in your eyes or any other untreated infections anywhere on your body (a type of infection that causes a sore on the eyelid or eye surface).
  • If you are breastfeeding a child or intend to become pregnant, let your doctor know. Call your doctor if you become pregnant while taking flunisolide.
  • Inform the surgeon or dentist that you are using flunisolide inhalation if you are having surgery, including dental surgery.
  • Your other health issues, such as asthma, arthritis, or eczema (a skin problem), could get worse if your oral steroid dosage is cut back. If this occurs or if you encounter any of the following symptoms at this time, let your doctor know right away: Extreme fatigue, muscle weakness, or pain, sudden pain in the stomach, lower body, or legs, appetite loss, weight loss, upset stomach, vomiting, diarrhoea, dizziness, fainting, depression, irritability, and skin darkening are all symptoms that might occur. During this time, your body may be less able to handle stressors like surgery, illness, severe asthma attacks, or injuries. If you become ill, call your doctor right away, and make sure any medical professionals who care for you are aware that you recently switched from an oral steroid to flunisolide inhalation. Keep a card with you or wear a medical identification bracelet to alert emergency responders to the possibility that you could require steroid treatment.
  • If you have never had chickenpox or measles and you have not received a vaccination against these diseases, let your doctor know. Avoid sick people, especially those who have the measles or chickenpox. Call your doctor right once if you are exposed to one of these infections or if you start to exhibit signs of one of these infections. To keep yourself safe from certain infections, you might need therapy.
  • You should be aware that flunisolide inhalation occasionally results in wheezing and breathing difficulties right away. Use your fast-acting (rescue) asthma medicine as soon as possible and call your doctor if this occurs. Inhaling flunisolide should not be done again unless your doctor instructs you to.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What should I do if I forget a dose?

Ignore the missed dose and carry on with my normal dosing routine. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Inhaling flunisolide may have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • White spots that hurt in the mouth or throat
  • Headache
  • Unwell throat
  • Runny or stuffed nose
  • Sinuses, throat, and nose swelling
  • Cough
  • Nosebleed
  • Discomfort while urinating

Some adverse effects can be very harmful. Get emergency medical attention if you develop any of the following symptoms or those listed in the SPECIAL PRECAUTIONS section.

  • Hives
  • Rash
  • Itching
  • Swelling of the lower legs, hands, feet, ankles, or face, neck, tongue, lips, eyes, or mouth
  • Hoarseness
  • Breathing or swallowing challenges
  • Stiffness or pain in the chest
  • Vision issues
  • Chills, pains, or a fever


Children who inhale flunisolide may experience slower growth. While using flunisolide inhalation, your child’s doctor will closely monitor your child’s growth. The hazards of giving your child this medication should be discussed with your child’s doctor.

Rarely, long-term users of flunisolide inhalation may develop cataracts or glaucoma. Ask your doctor how frequently you should have your eyes checked while undergoing therapy for flunisolide inhalation.

Your chance of developing osteoporosis may increase if you inhale flunisolide. Discuss the dangers of using this drug with your doctor.

Inhaling flunisolide may result in additional adverse effects. If you experience any strange issues while taking this drug, call your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep your flunisolide inhaler at room temperature, out of children’s reach, and away from excess heat and moisture (not in the bathroom). Keep the inhaler away from heat sources and open flames when storing it. Keep the inhaler out of the sun and the cold. Avoid puncturing the aerosol container and burning it when discarding it.

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at for additional information.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

What other information should I know?

Keep all of your appointments with your physician and the lab.

Do not share your medication with anybody else. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • AeroBid® Inhaler System
  • Aerospan® HFA
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