WARNING

Adzenys XR, a brand of amphetamine used primarily to treat attention deficit hyperactivity disorder (ADHD), carries several risks and potential side effects. Here’s a detailed breakdown:

• Appetite Loss: Many users experience reduced appetite, which can lead to weight loss. This is a common side effect of stimulant medications.
• Insomnia: Difficulty falling or staying asleep is frequent, especially if the medication is taken later in the day.
• Dry Mouth: A sensation of dryness in the mouth is another common side effect.
• Nausea: Some individuals might experience stomach discomfort or nausea.
• Cardiovascular Issues: Adzenys XR can increase heart rate and blood pressure, potentially leading to severe complications such as heart attack, stroke, or severe hypertension.
• Mental Health Effects: There’s a risk of exacerbating mental health conditions. Symptoms like anxiety, paranoia, or aggression may occur, and in rare cases, hallucinations or delusions may develop.
• Growth Suppression: In children, stimulant medications can potentially affect growth patterns, although this is usually monitored and managed by healthcare professionals.
• Dependence and Abuse: Amphetamines have a potential for abuse and dependence. Misuse of the medication can lead to serious addiction issues.
• Pre-existing Conditions: Individuals with a history of heart problems, high blood pressure, or psychiatric disorders should use Adzenys XR cautiously and under close medical supervision.
• Interactions with Other Medications: Adzenys XR can interact with other medications, such as monoamine oxidase inhibitors (MAOIs), potentially leading to severe reactions.
• Pregnancy and Breastfeeding: The safety of Adzenys XR during pregnancy and breastfeeding is not well-established, so it’s important to discuss this with a healthcare provider.

Regular monitoring by a healthcare provider is essential to manage side effects and adjust dosages as needed. If you or someone you know is taking Adzenys XR, it’s important to keep up with regular check-ups and report any unusual symptoms to a healthcare provider immediately.

Always consult with a healthcare professional for personalized advice and to discuss the risks and benefits in relation to your specific situation.

Why is this medication prescribed?

Adzenys XR, which is a brand name for an extended-release form of amphetamine, is primarily prescribed to treat Attention Deficit Hyperactivity Disorder (ADHD). It helps increase attention and decrease impulsiveness and hyperactivity in patients with ADHD. The extended-release formulation allows for a longer duration of effect compared to immediate-release forms, which can help with symptom management throughout the day.

How should this medicine be used?

Adzenys XR should be used exactly as prescribed by a healthcare provider. Here are some general guidelines for its use:

• Dosage: Follow the prescribed dosage carefully. Adzenys XR is usually taken once daily in the morning. The dose may be adjusted by your doctor based on your response and any side effects.
• Administration: Adzenys XR is available as an orally disintegrating tablet. Place the tablet on your tongue, and it will dissolve quickly. You don’t need to chew it or swallow it whole. It can be taken with or without food.
• Timing: Take it in the morning to avoid interference with sleep, as it can cause insomnia if taken too late in the day.
• Consistency: Try to take the medication at the same time each day to maintain steady levels in your system.
• Missed Dose: If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose; don’t double up to make up for a missed one.
• Storage: Store Adzenys XR at room temperature, away from moisture and heat.

Always consult your healthcare provider or pharmacist if you have any questions or concerns about taking Adzenys XR or if you experience any side effects.

Other uses for this medicine

Aside from its primary use for ADHD, Adzenys XR (amphetamine) is sometimes used off-label for other conditions, such as narcolepsy, but this is less common. Always use it only for the purposes prescribed by your healthcare provider.

What special precautions should I follow?

Special Precautions for Adzenys XR:

• Cardiovascular Health: Inform your doctor if you have any history of heart problems, high blood pressure, or other cardiovascular issues. Amphetamines can increase blood pressure and heart rate.
• Mental Health: If you have a history of mental health conditions, such as depression, anxiety, or bipolar disorder, discuss this with your doctor. Amphetamines can exacerbate certain mental health issues.
• Substance Use: Be cautious if you have a history of substance abuse or addiction, as amphetamines have the potential for abuse and dependency.
• Interactions: Let your doctor know about all other medications you are taking, including over-the-counter drugs, supplements, and herbal remedies. Amphetamines can interact with various medications, including some antidepressants and blood pressure medications.
• Pre-existing Conditions: Discuss any other pre-existing health conditions, such as thyroid problems or glaucoma, with your healthcare provider, as these can be affected by stimulant medications.
• Pregnancy and Breastfeeding: If you are pregnant, plan to become pregnant, or are breastfeeding, consult your doctor to discuss the potential risks and benefits.
• Allergies: Notify your doctor of any known allergies to medications, especially stimulants, as this can affect your suitability for Adzenys XR.
• Regular Monitoring: Regular follow-ups with your healthcare provider are important to monitor the effectiveness of the medication and any potential side effects.

Always follow your healthcare provider’s instructions and report any unusual symptoms or side effects promptly.

What special dietary instructions should I follow?

• Acidic Foods and Drinks: Be cautious with acidic foods and drinks (like citrus fruits and juices) as they can potentially affect the absorption of amphetamines. Try to maintain a balanced diet without drastic changes.
• Caffeine: Limit your intake of caffeine and other stimulants, as they can increase side effects like jitteriness and insomnia.
• Meal Timing: While Adzenys XR can be taken with or without food, consistency in how you take it in relation to meals can help in maintaining stable absorption levels.

What should I do if I forget a dose?

• If you realize you missed a dose and it’s still within the same day, take the missed dose as soon as you remember. If it’s close to the time for your next dose, skip the missed dose; do not take two doses at once to make up for the missed one.
• Try to take your medication at the same time each day to help remember and maintain effectiveness.
• If you frequently miss doses or have concerns about missed doses, discuss this with your healthcare provider for personalized advice.

What side effects can this medication cause?

Adzenys XR (amphetamine) can cause a range of side effects, some of which might be more common or severe than others. It’s important to monitor for these and report any significant concerns to your healthcare provider. Here are some potential side effects:

Common Side Effects:

• Insomnia: Difficulty sleeping or disrupted sleep patterns.
• Decreased Appetite: Reduced hunger or weight loss.
• Dry Mouth: A sensation of dryness in the mouth.
• Nausea or Vomiting: Upset stomach or gastrointestinal discomfort.
• Headache: General or severe headaches.
• Increased Heart Rate: Faster heart rate or palpitations.
• Nervousness or Anxiety: Feelings of restlessness or anxiety.

Less Common or Severe Side Effects:

• High Blood Pressure: Elevated blood pressure readings.
• Mood Changes: Severe mood swings, depression, or agitation.
• Psychosis: Hallucinations, paranoia, or delusions.
• Severe Cardiovascular Effects: Chest pain, shortness of breath, or irregular heartbeats.
• Allergic Reactions: Rash, itching, or swelling, particularly if it involves the face or throat.
• Movement Disorders: Unusual movements or tics.
• Serotonin Syndrome: A potentially life-threatening condition caused by excess serotonin, characterized by agitation, hallucinations, rapid heart rate, fever, excessive sweating, muscle spasms, and nausea.
• Circulation Problems: Cold fingers or toes, or color changes in extremities.

If you experience any severe or concerning side effects, it’s crucial to seek medical attention promptly. Regular check-ins with your healthcare provider can help manage side effects and adjust treatment as necessary.

What should I know about storage and disposal of this medication?

Storage and Disposal of Adzenys XR:

Storage:

• Temperature: Store Adzenys XR at room temperature, typically between 68°F and 77°F (20°C to 25°C).
• Humidity and Heat: Keep the medication away from excessive moisture and heat.
• Out of Reach: Store it in a secure place out of reach of children and pets to prevent accidental ingestion.

Disposal:

• Unused or Expired Medication: Do not throw away Adzenys XR in household trash. Check with your pharmacist or local waste disposal authorities for proper disposal methods.
• Drug Take-Back Programs: Many communities offer drug take-back programs or have drop-off locations for safely disposing of unused medications.
• FDA Guidelines: You can also check the FDA’s website for guidelines on drug disposal or use the “flush list” if instructed, but this is usually reserved for medications that pose a risk of overdose or abuse if left in the home.

In case of emergency/overdose

• Call Poison Control: In the event of an overdose, contact your local poison control center immediately. They can provide specific guidance based on the situation.
• Seek Medical Attention: If yo u suspect an overdose, go to the nearest emergency room or call emergency services right away.
• Symptoms of Overdose: Symptoms of an overdose may include severe agitation, hallucinations, rapid breathing, muscle twitching, or seizures. If you experience or observe these symptoms, seek emergency medical attention.

What other information should I know?

• Regular Check-Ups: Regularly follow up with your healthcare provider to monitor the effectiveness of the medication and any potential side effects.
• Medication Record: Keep an updated list of all medications you are taking and share this with your healthcare provider to avoid interactions.
• Avoid Alcohol and Other Stimulants: Alcohol and other stimulants can interact with Adzenys XR and increase the risk of side effects.
• Adherence to Prescription: Use Adzenys XR strictly as prescribed and do not adjust the dose or frequency without consulting your healthcare provider.
• Inform All Healthcare Providers: Make sure all your healthcare providers are aware of your use of Adzenys XR, especially if you are undergoing other treatments or procedures.

By following these guidelines and staying informed, you can use Adzenys XR safely and effectively. Always reach out to your healthcare provider with any questions or concerns.