WARNING

Advil PM is a combination of ibuprofen (a pain reliever) and diphenhydramine (an antihistamine). While it can be effective for relieving pain and helping with sleep, there are some risks to consider:

• Drowsiness and Impaired Function: Diphenhydramine can cause drowsiness, which might impair your ability to drive or operate machinery.
• Overuse Risks: Taking Advil PM too frequently can lead to overuse of ibuprofen, which can increase the risk of stomach ulcers, gastrointestinal bleeding, and kidney problems.
• Drug Interactions: Diphenhydramine can interact with other medications, potentially causing unwanted side effects.
• Allergic Reactions: Some people might experience allergic reactions to either ibuprofen or diphenhydramine.
• Dependence: Using sleep aids regularly might lead to dependence or difficulty sleeping without them.

Always use such medications as directed and consult a healthcare professional if you have any concerns.

Why is this medication prescribed?

Advil PM is a combination medication that typically contains ibuprofen and diphenhydramine. Here’s why each component is included:

• Ibuprofen: It is a nonsteroidal anti-inflammatory drug (NSAID) used primarily to reduce inflammation and relieve pain. It is commonly used for conditions such as arthritis, menstrual cramps, headaches, dental pain, and muscular aches.
• Diphenhydramine: This is an antihistamine that is used primarily to treat allergy symptoms (such as itching, rash, hay fever, watery eyes) and also as a sleep aid due to its sedative effects. It can help induce sleepiness and improve sleep quality.

When these two medications are combined in Advil PM, the intention is to provide relief from pain and inflammation (due to ibuprofen) along with the ability to aid sleep (due to diphenhydramine). Therefore, Advil PM is often prescribed or recommended for individuals who experience pain or discomfort and have difficulty falling asleep.

How should this medicine be used?

Advil PM is a combination of ibuprofen (a pain reliever) and diphenhydramine (an antihistamine used as a sleep aid). Here are general guidelines for using it:

• Dosage: Follow the dosage instructions on the package or as directed by your healthcare provider. Typically, the recommended dose for adults and children 12 years and older is 1 or 2 tablets before bedtime.
• Timing: Take Advil PM about 30 minutes before you plan to go to sleep. This allows time for the medication to start working.
• Duration: Use Advil PM for short-term relief only. If you need to use it for more than a few nights, consult with your doctor.
• Avoid Alcohol: Combining Advil PM with alcohol can increase the risk of side effects, such as drowsiness and impaired coordination.
• Interactions: Be cautious about using other medications that might interact with Advil PM, especially other sedatives or pain relievers.
• Health Conditions: If you have any pre-existing health conditions or are pregnant or breastfeeding, talk to your doctor before using Advil PM.

Always read and follow the instructions on the medication label or consult with a healthcare professional if you’re unsure.

Other uses for this medicine

• Fever Reduction: Ibuprofen, one of the components of Advil PM, is effective in reducing fever. It can be used to lower elevated body temperature associated with various conditions.
• Allergy Relief: Diphenhydramine, the other component, is an antihistamine that can alleviate symptoms of allergies such as itching, sneezing, and runny nose.

What special precautions should I follow?

When using Advil PM, consider the following special precautions:

• Medical Conditions: If you have any pre-existing health conditions, such as liver disease, kidney disease, high blood pressure, heart disease, or gastrointestinal issues, consult your doctor before use.
• Other Medications: Avoid using other sedatives, antihistamines, or medications that can cause drowsiness. Combining these with Advil PM can enhance side effects like drowsiness and impaired coordination.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, speak with your healthcare provider before using Advil PM.
• Alcohol: Avoid drinking alcohol while taking Advil PM. Alcohol can increase drowsiness and the risk of other side effects.
• Driving and Operating Machinery: Advil PM can cause drowsiness. Avoid driving or operating heavy machinery after taking it.
• Allergic Reactions: Be aware of potential allergic reactions to ibuprofen or diphenhydramine, such as rash, itching, or swelling. Seek medical attention if these occur.
• Duration of Use: Use Advil PM for the shortest duration necessary to alleviate symptoms. Prolonged use can increase the risk of side effects.
• Overdose: Do not exceed the recommended dose. An overdose of ibuprofen or diphenhydramine can be harmful. If you suspect an overdose, seek medical attention immediately.

Always consult with a healthcare provider if you have any concerns or questions about using Advil PM.

What special dietary instructions should I follow?

There are no specific dietary instructions associated with Advil PM. However, it’s advisable to take it with food or milk to help reduce the risk of stomach upset, particularly if you have a history of gastrointestinal issues.

What should I do if I forget a dose?

• If you miss a dose of Advil PM, take it as soon as you remember unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule.
• Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Advil PM can cause a range of side effects due to its combination of ibuprofen and diphenhydramine. Common side effects of advil pm include:

• Drowsiness: This is expected due to the diphenhydramine, which is a sedative.
• Dizziness: You might feel lightheaded or unsteady, especially when standing up quickly.
• Dry Mouth: Diphenhydramine can reduce saliva production, leading to a dry mouth.
• Upset Stomach: Ibuprofen can irritate the stomach lining, potentially causing nausea or stomach discomfort.
• Headache: Some people may experience headaches as a side effect.
• Constipation: Diphenhydramine can slow down bowel movements, leading to constipation.
• Blurred Vision: Antihistamines like diphenhydramine can occasionally cause blurred vision.
• Confusion or Impaired Coordination: Especially in older adults, diphenhydramine can cause confusion or difficulty with coordination.

Serious side effects are less common but can include:

• Allergic Reactions: Signs of an allergic reaction include rash, itching, swelling, severe dizziness, or trouble breathing.
• Gastrointestinal Issues: Persistent stomach pain, black or bloody stools, or vomit that looks like coffee grounds may indicate a serious issue with the stomach or intestines.
• Kidney or Liver Problems: Symptoms like unusual tiredness, swelling, or yellowing of the skin/eyes can indicate serious kidney or liver issues.

If you experience severe side effects or signs of an allergic reaction, seek medical attention immediately. For any persistent or concerning symptoms, contact a healthcare professional.

What should I know about storage and disposal of this medication?

Storage and Disposal:

• Storage:
  • Store Advil PM at room temperature, away from excessive heat and moisture. Do not store it in the bathroom where it can be exposed to humidity.
  • Store the medication in a secure place where children cannot access it.
• Disposal:
  • Dispose of Advil PM according to local regulations. Many communities have take-back programs for medications.
  • Use drug take-back programs or drop-off sites if available. These programs are often hosted by pharmacies or community organizations.
  • If the medication is in a container with personal information, remove or destroy the label before disposal.

In case of emergency/overdose

• Call 911: If you suspect an overdose or if someone is experiencing severe symptoms, call emergency services immediately.
• Poison Control Hotline: Call your local poison control center for guidance on what to do next. In the U.S., you can reach the Poison Control Center at 1-800-222-1222.
• Ibuprofen Overdose Symptoms: Nausea, vomiting, stomach pain, drowsiness, dizziness, headache, or ringing in the ears.
• Diphenhydramine Overdose Symptoms: Severe drowsiness, confusion, hallucinations, rapid heartbeat, or seizures.

What other information should I know?

• Check for Drug Interactions: If you are taking other medications or supplements, check for potential interactions with Advil PM.
• Consider Alternative Treatments: For sleep issues or pain, explore non-medication options like relaxation techniques, lifestyle changes, or physical therapy.
• Monitor Use: Use Advil PM for short periods to minimize the risk of dependency or side effects.
• Consult Healthcare Providers: If you have ongoing issues or concerns about using Advil PM, consult your healthcare provider for personalized advice and alternatives.

Always follow the instructions provided with the medication and consult with healthcare professionals if you have any questions or concerns.