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Aduhelm (Generic Aducanumab-avwa Injection)

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Why is this medication prescribed?

Amyloid beta plaque, a protein seen in the brains of those with Alzheimer’s disease, is reduced by the injection of aducanumab-avwa (a brain disease that slowly destroys the memory and ability to think, learn, communicate and handle daily activities). Mild cognitive impairment (MCI) and mild dementia are also conditions it is used to treat. The drug ducanumab-avwa injection belongs to the monoclonal antibody drug class. It functions by preventing the brain’s production of amyloid beta.

How should this medicine be used?

In a hospital or clinic, a doctor or nurse will administer the aducanumab-avwa injection as a solution (liquid) into a vein. Every four weeks, it is often given for more than an hour.

Depending on how you react to the drug and whether you encounter any adverse effects, your doctor may need to pause or halt your therapy. Tell your doctor how you are feeling during your therapy, please.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before receiving aducanumab-avwa injection,

  • If you have an allergy to aducanumab-avwa, any other drugs, or any of the ingredients in aducanumab-avwa injection, tell your doctor and pharmacist right away. For a list of the ingredients, consult the Medication Guide or speak with your pharmacist.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • If you have or have previously had any medical issues, let your doctor know.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you fall pregnant while having aducanumab-avwa injection.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What should I do if I forget a dose?

Call your doctor as soon as you can if you forget to show up for your aducanumab-avwa injection appointment. The injection doses of aducanumab-avwa should be spaced apart by at least 21 days.

What side effects can this medication cause?

The injection of aducanumab-avwa may have unwanted effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Diarrhea
  • Falls

Some adverse effects can be very harmful. Call your doctor right away if you encounter any of these symptoms, or seek emergency care:

  • Headache, fuzziness, wooziness, altered eyesight, or nausea
  • Swelling of the tongue, mouth, lips, or face
  • Hives

Other negative effects from injecting aducanumab-avwa are possible. If you have any strange side effects while taking this medicine, call your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your appointments with your physician and the lab. Before and during therapy, your doctor will prescribe certain tests to monitor how your body is responding to aducanumab-avwa, such as magnetic resonance imaging (MRI) scans, which utilise strong magnets to create images of the inside of the body.

Ask any inquiries you may have regarding aducanumab-avwa to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Aduhelm®
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