Why is this medication prescribed?

Adlyxin (also known as lixisenatide) is a medication used to help manage blood sugar levels in people with type 2 diabetes. It works by mimicking a natural hormone in the body that helps regulate blood sugar. Specifically, Adlyxin is a GLP-1 receptor agonist, which means it stimulates insulin release when blood sugar levels are high, reduces the amount of sugar produced by the liver, and slows down gastric emptying to help with appetite control. It’s often prescribed along with diet and exercise to improve overall blood sugar control.

How should this medicine be used?

Adlyxin is typically administered as a subcutaneous injection. Here’s a general guide on how it’s used:

• Dosage: The initial dose is usually 10 mcg once daily for 14 days. After that, the dose is increased to 20 mcg once daily.
• Injection Sites: You can inject Adlyxin into the thigh, abdomen, or upper arm. Rotate the injection sites to avoid irritation or lumps.
• Preparation: Check the medication to make sure it’s clear and free of particles. If using a prefilled pen, follow the instructions for priming the pen before your first use.
• Administration: Use the pen to inject the medication as directed. Clean the injection site with alcohol before injecting. Insert the needle at a 90-degree angle and press the button to release the medication.
• Timing: It’s typically recommended to take Adlyxin within an hour before the first meal of the day, but always follow your healthcare provider’s instructions.
• Storage: Store the unused pens in the refrigerator. Once in use, the pen can be kept at room temperature but should not be exposed to excessive heat or cold.

Always follow the specific instructions provided by your healthcare provider or included with the medication, and consult them if you have any questions or concerns about using Adlyxin.

Other uses for this medicine

Adlyxin is specifically approved for the treatment of type 2 diabetes. While it is mainly used to help manage blood sugar levels in people with this condition, its role is focused on diabetes management and it is not typically used for other conditions.

What special precautions should I follow?

Special Precautions for Adlyxin:

• Allergic Reactions: Inform your healthcare provider if you have any history of severe allergic reactions to GLP-1 receptor agonists or other components of Adlyxin.
• Pancreatitis: Be cautious if you have a history of pancreatitis (inflammation of the pancreas). Report any severe abdominal pain, nausea, or vomiting to your healthcare provider.
• Kidney Function: If you have kidney problems, your dosage may need to be adjusted. Regular monitoring of kidney function may be necessary.
• Thyroid Issues: Report any history of thyroid cancer or thyroid nodules to your healthcare provider. There may be an increased risk of thyroid tumors with GLP-1 receptor agonists, though this risk is still under study.
• Gastrointestinal Issues: If you have a history of gastrointestinal disorders or if you experience severe nausea or vomiting, let your healthcare provider know, as these can be side effects of Adlyxin.
• Drug Interactions: Inform your healthcare provider about all other medications you are taking, including over-the-counter drugs and supplements, to avoid potential interactions.
• Pregnancy and Breastfeeding: Discuss with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding, as the safety of Adlyxin in these situations has not been fully established.
• Hypoglycemia: Although Adlyxin is less likely to cause low blood sugar (hypoglycemia) when used alone, it is important to monitor your blood sugar levels regularly, especially if used with other diabetes medications that can cause hypoglycemia.

Always follow your healthcare provider’s guidance and report any unusual symptoms or side effects you experience while using Adlyxin.

What special dietary instructions should I follow?

• Follow a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. Adlyxin works best when combined with a healthy diet.
• Be mindful of carbohydrate intake, as it affects blood sugar levels. Your healthcare provider may give specific guidelines based on your individual needs.
• Adlyxin is usually taken within an hour before your first meal of the day. Ensure you follow this timing to maximize effectiveness.
• Maintain adequate hydration, as proper fluid intake can help with overall metabolic function.

What should I do if I forget a dose?

• If you remember within 1 hour of your missed dose, take it as soon as possible. If it’s almost time for your next dose, skip the missed dose. Do not double up on doses to make up for a missed one.
• Continue with your regular dosing schedule.
• If you’re unsure or have missed doses frequently, contact your healthcare provider for guidance on what to do next.

What side effects can this medication cause?

Adlyxin, like all medications, can cause side effects. Common and serious side effects include:

Common Side Effects:

• Nausea: This is one of the most frequent side effects and can decrease over time.
• Vomiting: May occur alongside nausea.
• Diarrhea: Some people experience gastrointestinal upset.
• Headache: Mild headaches can be a side effect.

Serious Side Effects:

• Pancreatitis: Symptoms include severe abdominal pain, nausea, and vomiting. Seek medical attention immediately if you experience these symptoms.
• Kidney Problems: Watch for symptoms like reduced urine output, swelling, or fatigue.
• Thyroid Tumors: There is a potential risk of thyroid tumors, including thyroid cancer. Report any lumps in the neck or persistent hoarseness.
• Severe Allergic Reactions: Symptoms include rash, itching, swelling, severe dizziness, or difficulty breathing.
• Hypoglycemia: If used with other medications that lower blood sugar, you may experience low blood sugar symptoms, such as shakiness, sweating, or confusion.
• Injection Site Reactions: You might experience redness, swelling, or pain at the injection site.

It’s important to report any side effects to your healthcare provider, especially if they are severe or persistent. They can provide guidance on how to manage side effects and determine if any adjustments to your treatment are necessary.

What should I know about storage and disposal of this medication?

Storage and Disposal of Adlyxin:

• Storage:
  • Unopened Pens: Store in the refrigerator (36°F to 46°F or 2°C to 8°C). Do not freeze.
  • In-Use Pens: Once in use, the pen can be kept at room temperature (up to 77°F or 25°C) for up to 14 days. Avoid exposing it to excessive heat or direct sunlight.
  • Protection: Keep the pen in its original packaging to protect it from light.
• Disposal:
  • Used Pens: Dispose of used pens in a puncture-proof sharps container or according to your local regulations for medical waste.
  • Do Not: Do not throw used pens in household trash or recycling bins.

In case of emergency/overdose

• Symptoms of Overdose: Symptoms may include severe nausea, vomiting, or signs of dehydration due to gastrointestinal issues.
• Contact Healthcare Provider: If you suspect an overdose or experience severe symptoms, contact your healthcare provider or seek medical attention immediately.
• Emergency Services: If necessary, call emergency services or go to the nearest emergency room.

What other information should I know?

• Blood Sugar: Regularly monitor your blood sugar levels as advised by your healthcare provider.
• Medical Check-Ups: Schedule regular appointments with your healthcare provider to review your diabetes management plan and adjust treatment as needed.
• Diet and Exercise: Follow a balanced diet and exercise plan as recommended to support blood sugar control and overall health.
• Avoid Alcohol: Limit alcohol consumption as it can affect blood sugar levels and interact with diabetes medications.
• Inform Providers: Inform your healthcare provider about all other medications, including over-the-counter drugs and supplements, to prevent potential interactions.
• Medical ID: Consider wearing a medical ID bracelet indicating that you have diabetes and are using Adlyxin.
• Patient Information Leaflet: Review the patient information leaflet provided with your medication for specific instructions and information.
• Healthcare Provider: Always follow the advice of your healthcare provider and contact them with any questions or concerns about your treatment.

Maintaining open communication with your healthcare provider and adhering to these guidelines can help ensure effective management of your condition while using Adlyxin.