Why is this medication prescribed?

Adcirca, which contains the generic drug tadalafil, is primarily prescribed to treat pulmonary arterial hypertension (PAH). PAH is a condition where the blood pressure in the lungs’ arteries is abnormally high, which can cause symptoms like shortness of breath and fatigue. Tadalafil works by relaxing the blood vessels in the lungs, which helps to lower blood pressure in the pulmonary arteries and improve symptoms. It’s also used to improve exercise capacity in people with PAH.

How should this medicine be used?

Adcirca (tadalafil) is typically taken as a tablet, and the dosage and frequency can vary based on the condition being treated. For pulmonary arterial hypertension (PAH), the usual dose is 40 mg once daily.

Here are some general guidelines for using Adcirca:

• Follow your doctor’s instructions: Always take the medication exactly as prescribed by your healthcare provider.
• Take with or without food: You can take Adcirca with or without food, but try to take it at the same time each day to help remember.
• Do not crush or chew: Swallow the tablet whole. Crushing or chewing the tablet can affect how the drug is absorbed.
• Missed dose: If you miss a dose, take it as soon as you remember, unless it’s almost time for your next dose. Do not take two doses at the same time to make up for a missed dose.
• Avoid interactions: Be cautious with other medications, especially nitrates or other medications for erectile dysfunction, as they can interact with tadalafil.

Always consult your healthcare provider or pharmacist if you have any questions or concerns about taking Adcirca.

Other uses for this medicine

Adcirca (tadalafil) is mainly prescribed for pulmonary arterial hypertension (PAH), but it can also be used for other conditions related to the blood vessels and erectile dysfunction. However, its use for conditions other than PAH should always be under the guidance of a healthcare provider.

What special precautions should I follow?

Special Precautions:

• Medical History: Inform your doctor if you have a history of heart problems, stroke, liver or kidney disease, low blood pressure, or if you are prone to bleeding disorders. Tadalafil can have effects on the cardiovascular system.
• Drug Interactions: Be cautious if you are taking other medications, especially nitrates (used for chest pain) or alpha-blockers (for high blood pressure or prostate issues), as these can cause a dangerous drop in blood pressure when used with tadalafil.
• Allergies: Let your doctor know if you have any known allergies to tadalafil or other medications.
• Side Effects: Be aware of possible side effects like headache, flushing, upset stomach, or muscle pain. Serious side effects, although rare, can include severe allergic reactions, prolonged erection, or vision changes.
• Alcohol and Grapefruit: Limit alcohol intake and avoid grapefruit products, as they can affect how tadalafil works and increase the risk of side effects.
• Pregnancy and Breastfeeding: If you are pregnant, plan to become pregnant, or are breastfeeding, discuss with your doctor whether Adcirca is appropriate for you, as its effects in these situations are not well-studied.
• Lifestyle: Maintain a healthy lifestyle, including regular exercise and a balanced diet, to support the effectiveness of the medication and overall health.

Always consult your healthcare provider for personalized advice and follow their recommendations closely.

What special dietary instructions should I follow?

• Alcohol: Limit alcohol consumption. Excessive drinking can increase the risk of side effects like dizziness and lightheadedness.
• Grapefruit: Avoid grapefruit and grapefruit juice, as they can interact with tadalafil and increase the risk of side effects.
• General Diet: Maintain a balanced diet to support overall health and the effectiveness of the medication.

What should I do if I forget a dose?

• Timing: If you miss a dose of Adcirca, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular schedule.
• Do Not Double Dose: Do not take two doses at the same time to make up for a missed dose, as this can increase the risk of side effects.

What side effects can this medication cause?

Adcirca (tadalafil) can cause a range of side effects, some of which may be mild, while others could be more serious. Common and less serious side effects include:

• Headache
• Flushing
• Upset stomach or indigestion
• Back pain
• Muscle aches
• Nasal congestion
• Dizziness

Serious Side Effects:

• Prolonged Erection (Priapism): An erection lasting more than 4 hours can be painful and requires immediate medical attention to prevent long-term damage.
• Sudden Vision Loss: This could be a sign of a serious eye condition called non-arteritic anterior ischemic optic neuropathy (NAION).
• Hearing Loss: Sudden decrease or loss of hearing, sometimes with ringing in the ears or dizziness.
• Severe Allergic Reactions: Symptoms include rash, itching, swelling, severe dizziness, or trouble breathing.
• Chest Pain: Can be related to cardiovascular issues and requires immediate medical attention.

If you experience any severe side effects or symptoms that concern you, contact your healthcare provider or seek emergency medical help right away. For less serious side effects that persist or become bothersome, your healthcare provider can offer guidance on managing them.

What should I know about storage and disposal of this medication?

Storage and Disposal:

• Storage:
  • Temperature: Store Adcirca at room temperature, typically between 68°F and 77°F (20°C to 25°C).
  • Humidity: Keep it away from excess moisture and humidity; do not store in the bathroom.
  • Original Container: Keep the medication in its original container to protect it from light and moisture.
• Disposal:
  • Medication Take-Back Programs: Dispose of unused or expired medication through a drug take-back program if available in your area.
  • FDA Guidelines: If a take-back program is not available, follow FDA guidelines for disposal: mix the medication with an undesirable substance (like used coffee grounds or cat litter) and place it in a sealed bag or container before throwing it in the trash.
  • Do Not Flush: Do not flush Adcirca down the toilet or pour it into a drain unless instructed to do so.

In case of emergency/overdose

• Symptoms of Overdose: Symptoms may include severe dizziness, fainting, prolonged erection (priapism), or severe back pain.
• Contact Emergency Services: Call emergency services or go to the nearest emergency room if you suspect an overdose.
• Provide Information: Be ready to provide information about the medication and the amount taken.

What other information should I know?

• Regular Check-ups: Regular follow-up appointments with your healthcare provider are essential to monitor the effectiveness and adjust dosage if needed.
• Inform Healthcare Providers: Make sure to inform any healthcare provider that you are taking Adcirca, especially before undergoing any surgeries or procedures.
• Drug Interactions: Be cautious of potential interactions with other medications, including over-the-counter drugs and herbal supplements. Always inform your healthcare provider about all the medications and supplements you are taking.
• Lifestyle Changes: Adcirca works best when combined with other lifestyle changes such as regular exercise, a healthy diet, and avoiding smoking or excessive alcohol consumption.
• Emergency Contact: Have the contact information for your healthcare provider or a local poison control center readily available in case of emergencies.

If you have any specific questions or concerns about Adcirca, your healthcare provider or pharmacist can provide detailed and personalized information.