Adults with moderate to severe eczema, also known as atopic dermatitis, who are unable to utilise topical treatments for their condition or whose eczema has not responded to topical medications can receive a talokinumab injection to treat their condition. The drug talokinumab belongs to a group of drugs known as interleukin-13 receptor inhibitors. It functions by preventing the body’s interleukin-13, a protein that triggers inflammation, from acting.

The solution (liquid) form of talokinumab injection is intended for subcutaneous injection (under the skin). It is typically administered as a four-injection first dosage, two injections every two weeks for the first 16 weeks afterward, and then two injections every four weeks if necessary. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Tralokinumab injection should only be used as prescribed. Never inject more, less, or more frequently than your doctor has instructed.

Your doctor’s office may be where you get your first tralokinumab injection. After that, you might be able to administer the injections of the drug yourself at home or with the help of a friend or relative. Your doctor will demonstrate how to inject tralokinumab injection subcutaneously if you plan to administer the drug yourself at home or have a friend or family member administer it on your behalf. Before injecting the medicine, read the tralokinumab injection’s written usage instructions.

Injections of talokinumab are sold in prefilled syringes. Each syringe should only be used once to inject the entire solution within. Reusing or capping pre-filled syringes with tralokinumab is not advised. Used syringes should be disposed of in a container that won’t puncture. How to get rid of the puncture-resistant container should be discussed with your doctor or pharmacist.

Except for your navel and the region 2 inches (5 cm) around it, you can inject tralokinumab injection anyplace on your front thighs or stomach. The individual administering the injection to you may also administer the drug into your upper arms. Each tralokinumab injection should be administered at a new place on the same part of the body, at least an inch apart from the previous site. Change the location of the injection site for the subsequent dose. Avoid injecting the drug into skin that is injured, bruised, scarred, or too fragile.

When using pre-filled syringes that have been chilled, place the syringe on a flat surface, leaving the needle cap on, and wait 30 minutes before injecting the medication to let it thaw to room temperature. Never attempt to reheat the drug by putting it in a hot water bath, microwave, or any other device. Tralokinumab syringes shouldn’t be shaken.

Before injecting tralokinumab, always check the injection solution. Check that the liquid is clear or slightly pearly, colourless, or pale yellow, and that the expiration date has not gone. If the syringe is past its expiration date, the liquid is muddy, discoloured, or contains noticeable coloured or sized particles, do not use it.

For a copy of the manufacturer’s information for the patient, ask your pharmacist or doctor.

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

Before using tralokinumab injection,

• If you have an allergy to tralokinumab, any other drugs, or any of the ingredients in tralokinumab injection, let your doctor and pharmacist know right away. Request a list of the components from your pharmacist.
• Inform your doctor and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products that you are now taking or intend to use.
• If you have any eye issues or have ever had a parasite infection, let your doctor know.
• Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor right away if you get pregnant while taking tralokinumab injection.
• Find out from your doctor if you require any vaccines. Avoid getting any shots without first consulting your doctor.

Keep eating normally unless your doctor instructs you otherwise.

If you forget to take a dose, take the next one right away, and then go back to your regular dosing plan.

There may be negative effects from talokinumab. If any of these symptoms are severe or do not go away, let your doctor know right once:

• Cough, sore throat, runny nose, and sneezing
• Red, itchy, and watery eyes
• Redness, swelling, and pain at the injection site

Some adverse effects can be very harmful. Call your doctor right away if any of these symptoms occur to you:

• Breathing issues, mouth, cheek, or tongue swelling, rash, hives, itching, dizziness, or fainting
• Eye discomfort or vision alterations

There may be more adverse effects from talokinumab. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

Keep this medication tightly closed in the original container and out of the reach of children. Tralokinumab injection should be kept in the fridge and shielded from light. Additionally, tralokinumab injectable may be kept for up to 14 days under darkness and at room temperature (up to 77°F [25°C]). Tralokinumab injectable needs to be thrown away after being kept at room temperature for more than 14 days without being used. Avoid freezing it. Any medication that has been frozen should be thrown away.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning. http://www.upandaway.org

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at http://goo.gl/c4Rm4p for additional information.

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Keep all of your doctor’s appointments.

Do not share your medication with anybody else. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.