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Actron (Generic Ketoprofen)

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Nonsteroidal anti-inflammatory drugs (NSAIDs) other than aspirin, such ketoprofen, may increase a person’s chance of suffering a heart attack or stroke compared to a person who does not take them. These occurrences could be fatal and could occur suddenly. For those who take NSAIDs for an extended period of time, this risk may be larger. If you have recently experienced a heart attack, avoid taking an NSAID like ketoprofen unless your doctor specifically instructs you to. Inform your doctor if you smoke, have high cholesterol, high blood pressure, or diabetes, or if you or anyone in your family has ever suffered from heart disease, a heart attack, or a stroke. If you suffer any of the following symptoms, seek emergency medical attention right away: chest pain, shortness of breath, weakness on one side or area of the body, or slurred speech.

Ketoprofen should not be taken just before or right after having a coronary artery bypass graft (CABG; a form of heart surgery).

Ketoprofen is one example of an NSAID that might result in stomach or intestine holes, bleeding, or ulcers. These issues could arise at any point during therapy, without any prior symptoms, and could be fatal. People who take NSAIDs for an extended period of time, are older, are in poorer health, or consume more than three alcoholic beverages per day while using ketoprofen may be at higher risk. If you consume a lot of alcohol or take any of the following medications, let your doctor know: oral steroids such dexamethasone, methylprednisolone (Medrol), and prednisone (Rayos); anticoagulants (‘blood thinners’) like warfarin (Coumadin, Jantoven); aspirin; other NSAIDs like ibuprofen (Advil, Motrin), or naproxen (Aleve, Naprosyn); selective Serotonin Reuptake Inhibitors (SSRIs) include citalopram (Celexa), fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), and sertraline (Zoloft), as well as Serotonin Norepinephrine Reuptake Inhibi (Effexor XR). Additionally, let your doctor know if you suffer from bleeding problems, ulcers, or stomach or intestine bleeding. Stop using ketoprofen and contact your doctor if you notice any of the following signs: stomach pain, heartburn, bloody or coffee-ground-looking vomit, blood in the stool, or tarry or black faeces are all symptoms of this condition.

Keep all of your appointments with your physician and the lab. Your doctor will keep a close eye on your symptoms and possibly recommend a few tests to see how your body is responding to the ketoprofen. Inform your physician about your feelings so that they can prescribe the ideal dosage of medication to cure your problem with the least chance of negative side effects.

The manufacturer’s patient information sheet (Medication Guide) will be sent to you by your doctor or pharmacist when you start taking prescription ketoprofen and each time you refill it. If you have any questions, carefully read the material and contact your doctor or pharmacist. The Medication Guide is also available on the Food and Drug Administration (FDA) website at

Why is this medication prescribed?

In order to treat rheumatoid arthritis and osteoarthritis (arthritis brought on by a breakdown of the lining of the joints), prescription ketoprofen is utilised (arthritis caused by swelling of the lining of the joints). Menstrual discomfort is one more condition for which prescription ketoprofen capsules are used to treat pain (pain that occurs before or during a menstrual period). Ketoprofen, a drug available over-the-counter, is used to treat mild aches and pains such headaches, menstrual cramps, toothaches, the common cold, muscle and backaches, as well as to lower fever. Ketoprofen belongs to the group of drugs known as NSAIDs. It functions by halting the body’s production of a chemical responsible for inflammation, fever, and discomfort.

How should this medicine be used?

Long-acting (extended-release) capsules and capsules for oral administration are both available for ketoprofen on prescription. When treating pain or arthritis, the capsules are typically taken every 6 to 8 hours as needed. Typically, one extended-release capsule is used each day. If you frequently use ketoprofen, take it at roughly the same time each day.

Ketoprofen without a prescription is available as an oral tablet. Every 4 to 6 hours as needed, it is often taken with a full glass of water or another drink.

Ask your doctor or pharmacist to explain any instructions on the packaging or prescription label that you do not understand, and carefully follow them. Take ketoprofen as advised by your doctor. Never take it in larger or less amounts or more frequently than recommended by your doctor or the label.

To avoid stomach distress, ketoprofen may be taken with food or milk. To lessen stomach distress, your doctor might also advise you to take ketoprofen together with an antacid.

If you are prescribed ketoprofen, your doctor may start you out on a typical dose and then gradually increase or decrease it based on how well you respond to the drug and any adverse effects you encounter. Pay close attention to these guidelines.

If your symptoms worsen, you have new or unexpected symptoms, the area of your body that was hurting turns red or swollen, your pain lasts longer than 10 days, or your fever lasts longer than three days, stop taking nonprescription ketoprofen and notify your doctor.

Other uses for this medicine

Ketoprofen is also occasionally used to treat other conditions, such as shoulder pain brought on by bursitis (inflammation of a fluid-filled sac in the shoulder joint) and tendinitis (inflammation of the tissue that connects muscles to bones), Reiter’s syndrome (condition in which many parts of the body, such as the joints, eyes, genitals, bladder, and digestive system become swollen), juvenile rheumatoid arthritis (a type of (attacks of joint pain caused by a build-up of certain substances in the joints). The dangers of using this drug for your illness should be discussed with your doctor.

Ask your doctor or pharmacist for more details if you’re interested in using this drug for any other conditions.

What special precautions should I follow?

Before taking ketoprofen,

  • If you have an allergy to any of the inactive chemicals in ketoprofen capsules or extended-release capsules, aspirin, other NSAIDs like ibuprofen (Advil, Motrin), naproxen (Aleve), or any other medications, let your doctor and pharmacist know right once. Request a list of the inactive components from your pharmacist.
  • Inform your doctor and pharmacist about any prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Mention the medications listed in the IMPORTANT WARNING section as well as any of the following: angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin, in Lotrel), captopril, enalapril (Vasotec, in Vaseretic), fosinopril, lisinopril (in Zestoretic), moexipril (Univasc), perindopril (Aceon, in Prestalia), quinapril (Accupril, in Quinaretic); angiotensin-receptor blockers such as candesartan (Atacand, in Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, in Avalide), losartan (Cozaar, in Hyzaar), olmesartan (Benicar, in Azor, in Benicar HCT, in Tribenzor), telmisartan (Micardis, in Micardis HCT, in Twynsta), diabetic drugs, diuretics (‘water pills,’ lithium (Lithobid), methotrexate (Otrexup, Rasuvo, Trexall), phenytoin (Dilantin, Phenytek), and probenecid (Probalan). Your doctor might need to adjust your medication doses or keep a closer eye out for any negative side effects.
  • Inform your doctor if you have or have ever had any of the conditions listed in the IMPORTANT WARNING section, as well as asthma, particularly if you also suffer from heart failure, swelling of the hands, arms, feet, ankles, or lower legs, liver disease, or renal illness.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. If ketoprofen is consumed after 20 weeks of pregnancy, it could harm the foetus and complicate delivery. Unless specifically instructed to do so by your doctor, avoid using ketoprofen during or after the first 20 weeks of pregnancy. Call your doctor if you become pregnant while taking ketoprofen.
  • If you are 75 years of age or older, discuss with your doctor the advantages and disadvantages of taking ketoprofen. Never take this drug for longer than your doctor has prescribed or at a higher dose.
  • Inform your doctor or dentist that you are taking ketoprofen if you are having surgery, including dental surgery.

What special dietary instructions should I follow?

Maintain your regular diet unless your doctor instructs you otherwise.

What should I do if I forget a dose?

As soon as you recall, take the missed dose. Skip the missed dose and carry on with your regular dosing plan, nevertheless, if it is almost time for the subsequent dose. You shouldn’t take two doses to make up for one.

What side effects can this medication cause?

Ketoprofen could have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Constipation
  • Diarrhea
  • Infections in the mouth
  • Headache
  • Dizziness
  • Nervousness
  • Drowsiness
  • Having trouble falling or staying asleep
  • An earache that ringers

There could be some severe negative effects. Call your doctor right away if you have any of the following symptoms or those listed in the IMPORTANT WARNING section. Ketoprofen shouldn’t be taken any further unless you consult with your doctor.

  • Alterations to vision
  • Unaccounted-for weight gain
  • Respiratory issues or shortness of breath
  • Abdomen, feet, ankles, or lower legs swelling
  • Fever
  • Blisters
  • Rash
  • Itching
  • Hives
  • Eye, face, lip, tongue, throat, arm, or hand swelling
  • Hoarseness
  • Having trouble swallowing
  • Excessive fatigue
  • Uncommon bruising or bleeding
  • Not enough energy
  • Reduced appetite
  • Nausea
  • Upper right stomach region discomfort
  • Flu-like signs
  • The skin or eyes turning yellow
  • Fast heartbeat
  • Pale skin
  • Urine that is cloudy, discoloured, or bloody
  • Back ache
  • Uncomfortable or challenging urinating


Other negative effects of ketoprofen are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Store it away from excessive heat and moisture at room temperature (not in the bathroom).

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at for additional information.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Overdose signs could include the following:

  • Not enough energy
  • Drowsiness
  • Nausea
  • Vomiting
  • Abdominal pain
  • Sluggish breathing
  • Seizures
  • Coma

What other information should I know?

Inform the lab staff and your doctor that you are taking ketoprofen prior to any laboratory test.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Actron®
  • Nexcede®
  • Orudis®
  • Orudis® KT
  • Oruvail®
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