Why is this medication prescribed?

Actonel, or its generic version risedronate, is a medication used to treat and prevent osteoporosis. Osteoporosis is a condition characterized by weakened bones that are more prone to fractures. Risedronate works by slowing down the activity of the cells that break down bone, which helps to maintain bone density and reduce the risk of fractures. It’s often prescribed to postmenopausal women, people taking corticosteroids, and others at high risk for bone loss.

How should this medicine be used?

Actonel (risedronate) is a medication used to treat and prevent osteoporosis. Here’s how it should be used:

• Dosage: Typically, it’s taken once a week or once a month, depending on your doctor’s instructions. There are also daily dosing options.
• Timing: Take Actonel first thing in the morning, on an empty stomach.
• Instructions: Swallow the tablet whole with a full glass of plain water (not mineral water). Do not chew, crush, or suck on the tablet. After taking it, wait at least 30 minutes before eating, drinking, or taking any other medications or supplements. Remain upright (sitting or standing) for at least 30 minutes after taking the medication to help prevent irritation of the esophagus.
• Hydration: Ensure you’re drinking enough fluids throughout the day, as staying well-hydrated helps with the medication’s effectiveness and reduces the risk of side effects.
• Regular Monitoring: Follow your doctor’s recommendations for bone density tests and other monitoring to assess how well the medication is working.

Always follow your healthcare provider’s specific instructions and consult them if you have any questions or experience any side effects.

Other uses for this medicine

In addition to treating osteoporosis, Actonel can also be used for:

• Paget’s Disease of Bone: A condition where bones become enlarged and deformed.
• Glucocorticoid-Induced Osteoporosis: Osteoporosis caused by long-term use of corticosteroid medications.

What special precautions should I follow?

Special Precautions for Actonel:

• Esophageal Issues: If you have any problems with your esophagus (like difficulty swallowing or severe heartburn), inform your doctor, as Actonel can cause irritation or inflammation.
• Kidney Function: Actonel is not recommended if you have severe kidney impairment. Your doctor may need to adjust the dosage based on your kidney function.
• Dental Health: There is a rare risk of jawbone problems (osteonecrosis) associated with bisphosphonates like Actonel. It’s important to have a dental check-up and inform your dentist that you’re taking Actonel, especially if you need dental procedures.
• Calcium and Vitamin D: Ensure you get enough calcium and vitamin D, as they are important for bone health. Your doctor might recommend supplements.
• Pregnancy and Breastfeeding: Actonel is not recommended during pregnancy or breastfeeding. Discuss alternative treatments with your doctor if you are pregnant or plan to become pregnant.
• Other Medications: Inform your doctor about all the medications and supplements you’re taking, as some can interact with Actonel.
• Gastrointestinal Issues: If you have a history of gastrointestinal issues, such as ulcers, you should use Actonel with caution.

Always follow your healthcare provider’s advice and report any unusual symptoms or side effects.

What special dietary instructions should I follow?

• Timing: Take Actonel on an empty stomach, first thing in the morning, with a full glass of plain water (not mineral water).
• Upright Position: Remain upright (sitting or standing) for at least 30 minutes after taking Actonel to minimize the risk of esophageal irritation.
• Avoid Certain Foods and Beverages: Wait at least 30 minutes before eating, drinking, or taking any other medications or supplements, as certain foods and drinks can affect the absorption of Actonel.

What should I do if I forget a dose?

• Weekly Dosing: If you miss a weekly dose, take it as soon as you remember. Then, resume your regular weekly schedule. Do not take two doses on the same day.
• Monthly Dosing: If you miss a monthly dose, take it as soon as you remember. Then, resume your regular monthly schedule. Do not take two doses in one day.
• Daily Dosing: If you miss a daily dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double up on doses.

What side effects can this medication cause?

Actonel (risedronate) can cause a range of side effects. Some are common and manageable, while others are less common but may require medical attention. Here are the potential side effects:

Common Side Effects:

• Gastrointestinal Issues: Nausea, abdominal pain, constipation, or diarrhea.
• Headache: Mild to moderate headaches.
• Muscle or Joint Pain: Discomfort in muscles or joints.

Less Common but Serious Side Effects:

• Esophageal Irritation: Symptoms include severe heartburn, pain when swallowing, or difficulty swallowing.
• Osteonecrosis of the Jaw: Rare but serious, involving jaw pain, swelling, or infection.
• Severe Bone, Joint, or Muscle Pain: Intense pain in bones, joints, or muscles.
• Low Calcium Levels: Symptoms might include muscle cramps, numbness, or tingling.
• Kidney Problems: Symptoms include changes in urine output or pain in the lower back.
• Severe Allergic Reactions: Symptoms may include rash, itching, swelling, severe dizziness, or trouble breathing.
• Unusual Thigh Bone Fractures: Atypical fractures in the thigh bone, which can occur with long-term use.
• Eye Inflammation: Symptoms include pain, redness, or swelling of the eyes.

If you experience severe or unusual symptoms, contact your healthcare provider promptly. For most side effects, your doctor can provide guidance on how to manage them or adjust your treatment if necessary.

What should I know about storage and disposal of this medication?

Storage and Disposal of Actonel:

• Storage:
  • Keep Actonel at room temperature, away from heat and moisture.
  • Store it in its original container, tightly closed.
  • Keep it out of reach of children and pets.
• Disposal:
  • Do not flush medications down the toilet or pour them into a drain unless instructed to do so.
  • Dispose of unused or expired medication according to local regulations. Many pharmacies have drug take-back programs or disposal kiosks.

In case of emergency/overdose

• Emergency: If you experience severe symptoms such as chest pain, difficulty breathing, severe gastrointestinal symptoms, or signs of a severe allergic reaction (rash, itching, swelling, severe dizziness), seek immediate medical attention.
• Overdose: If you suspect an overdose of Actonel, contact your local poison control center or emergency medical services right away. Symptoms of an overdose might include severe gastrointestinal pain, nausea, or vomiting.

What other information should I know?

• Regular Monitoring: Keep up with regular check-ups and bone density tests as advised by your doctor to monitor the effectiveness of the treatment.
• Drug Interactions: Be aware of potential interactions with other medications or supplements. Always inform your healthcare provider of all the drugs and supplements you are taking.
• Adherence to Instructions: Follow the medication instructions closely to maximize benefits and minimize side effects.
• Inform Healthcare Providers: Inform any healthcare provider or dentist you visit that you are taking Actonel, especially before any surgical or dental procedures.

If you have any concerns or questions about your medication, consult with your healthcare provider for personalized advice and guidance.