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Abaloparatide Injection

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WARNING

Injecting abaloparatide may result in laboratory rats developing osteosarcoma (bone cancer). It is unknown if abaloparatide injection raises the likelihood that people may contract this malignancy. Inform your physician if you currently have or have previously had Paget’s disease, bone cancer or cancer that has metastasized to the bone, radiation therapy for the bones, elevated blood levels of alkaline phosphatase, or if you are a child or young adult whose bones are still developing. Call your doctor right away if you have any of the following symptoms: Any persistent pain in your body, including pain in your bones, lumps or swelling under your skin that are new or unusual and painful to the touch.

Your doctor may advise you not to take abaloparatide injection or any associated drugs like teriparatide injection (Forteo) for longer than a total of 2 years in your lifetime due to the risk of osteosarcoma with this medicine.

When you start receiving treatment with abaloparatide injection and every time your prescription is renewed, your doctor or pharmacist will provide you the manufacturer’s patient information leaflet (Medication Guide). If you have any questions, carefully read the material and contact your doctor or pharmacist. The Medication Guide is also available on the manufacturer’s website or the Food and Drug Administration (FDA) website.

Discuss the dangers of using abaloparatide injection with your doctor.

Why is this medication prescribed?

Women who have undergone menopause (the “change in life,” the end of menstrual periods), who are at high risk of fractures (broken bones), or who could not be successfully treated with other medications are used to treat osteoporosis, a condition in which the bones become thin and weak and break easily. A synthetic version of the human hormone parathyroid hormone is present in abaloparatide injection (PTH). It functions by encouraging the body to produce new bone while boosting bone strength and density (thickness).

How should this medicine be used?

Abaloparatide injection is available as a liquid to inject beneath the skin (under the skin). It is typically administered once daily. Use the same time each day to administer the abaloparatide injection. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Administer the abaloparatide injection as prescribed. Use it only as directed by your doctor, neither more nor less often.

You can administer the baloparatide injection yourself, or you can ask a friend or family member to do it for you. Be sure to thoroughly read the manufacturer’s instructions before administering abaloparatide injection for the first time. To learn how to inject a medicine, ask your doctor or pharmacist to demonstrate it to you or the person doing the injecting. If you have any concerns regarding how to inject this drug, be sure to consult your doctor or pharmacist.

The abaloparatide injection comes in a pen that has 30 doses of medicine in it. Do not use another syringe to transfer the drug. Even if your pen still has unused prescription inside, dispose of it 30 days after first opening.

Abaloparatide should be injected into the lower stomach region. Do not administer your injection within two inches of your belly button. Discuss with your doctor how to switch up your injection location each time. Abaloparatide should not be injected into your muscles or veins. Never administer an injection to skin that is brittle, bruised, red, scaly, rigid, or covered with scars or stretch marks.

Before injecting your abaloparatide, always check it. It need to be transparent and colourless. Abaloparatide injection should not be used if it contains particles, is foggy, or is coloured.

Make sure you are aware of any additional equipment, such as needles, that you will require to inject your medication. What kind of needles you will need to inject your medication into your body, ask your doctor or pharmacist. Never share pens or needles, and never reuse them. Always discard the needle soon away after administering the medication. Needles should be disposed of in a container that won’t puncture. For disposal instructions on the puncture-resistant container, consult your doctor or pharmacist.

You should be aware that abaloparatide injection may result in nausea, a fast or pounding heartbeat, dizziness, lightheadedness, and fainting if you rise up too quickly from a reclining position. This often happens 4 hours after taking your medication and usually goes gone in a few hours. Your initial doses of abaloparatide injection should be administered in a location where you can immediately sit or lay down if necessary.

Vitamin D and calcium supplements may be suggested by your physician for you to take while undergoing treatment.

Although it doesn’t treat osteoporosis, a baloparatide injection can manage it. Even if you feel better, continue administering the abaloparatide injection. Without consulting your doctor, do not stop taking the abaloparatide injectable.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before receiving abaloparatide injection,

  • If you have an allergy to abaloparatide, any other drugs, or any of the ingredients in abaloparatide injection, let your doctor and pharmacist know right away. For a list of the ingredients, consult the Medication Guide or speak with your pharmacist.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • Inform your doctor if you have or have ever had kidney stones, hyperparathyroidism (a condition in which the body produces excessive amounts of parathyroid hormone, a natural substance needed to control the amount of calcium in the blood), or any other condition that causes you to have too much calcium in the blood.
  • You should be aware that women should only use a baloparatide injection after menopause, when they are no longer able to become pregnant or nurse. Neither breastfeeding nor using abaloparatide injection while pregnant are recommended.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What should I do if I forget a dose?

As soon as you remember to take the missed dose that day, do so. In contrast, omit the missing dose if the next day has already passed and carry on with your regular dosing regimen. Never administer more than one dose in a single day.

What side effects can this medication cause?

The injection of abaloparatide may have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Dizziness
  • Spinning feeling
  • Headache
  • Tiredness
  • Lower abdominal discomfort
  • Where the drug was injected, there may be signs of inflammation, soreness, or redness

Some adverse effects can be very harmful. Call your doctor right away if you have any of these signs or any of those in the IMPORTANT WARNING section:

  • High blood calcium symptoms include: nausea, diarrhoea, constipation, fatigue, and muscle aches
  • Lower back or stomach discomfort
  • Unpleasant urination
  • Urine with blood in it

Other negative consequences from a baloparatide injection are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Abaloparatide pens should be kept in the refrigerator before to use; do not freeze. Abaloparatide pens should be kept at room temperature for up to 30 days following the initial use. After 30 days at room temperature, throw away the pen.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning. http://www.upandaway.org

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at http://goo.gl/c4Rm4p for additional information.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Overdose signs could include the following:

  • Nausea
  • Vomiting
  • Constipation
  • Dizziness
  • Headache
  • Standing and feeling dizzy and faint
  • lack of energy
  • muscle tremor

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body’s response to abaloparatide injection.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand names

  • Tymlos®
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