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A-poxide (Generic Chlordiazepoxide)

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WARNING

Using some drugs with chlordiazepoxide may raise the risk of serious or life-threatening respiratory issues, sedation, or coma. Inform your physician if you are currently taking or intend to take any opiate medications, including codeine (in Triacin-C, Tuzistra XR) or hydrocodone (in Anexsia, Norco, or Zyfrel) for coughing or codeine (in Fiorinal) for pain. Other opiate medications include fentanyl (Actiq, Duragesic, Subsys), hydromorphone (Dilaudid, Exalgo) (Conzip, Ultram, in Ultracet). Your doctor will closely monitor you and may need to adjust the dosage of your drugs. Call your doctor right away if you experience any of the following symptoms while taking chlordiazepoxide with any of these drugs: unusual dizziness, lightheadedness, excessive drowsiness, slowed or laboured breathing, or unresponsiveness. If you are unable to seek treatment on your own, make sure your carer or family members are aware of any symptoms that may be dangerous so they can contact the doctor or emergency services.

Chlordiazepoxide may lead to addiction. Never exceed the recommended dosage, frequency, or duration. Always follow your doctor’s instructions. Inform your doctor if you use or have ever used illicit drugs, consumed excessive amounts of alcohol, or have ever misused any prescription drugs. Don’t consume alcohol or use illicit substances while receiving treatment. Using illicit substances or alcohol while taking chlordiazepoxide also increases your risk of developing these severe, sometimes fatal side effects. Also let your doctor know if you suffer from depression or any other mental disease now or in the past.

Particularly if you use chlordiazepoxide for a number of days to a number of weeks, it may result in physical dependence, a condition in which unpleasant physical symptoms appear if a medication is abruptly withdrawn or taken in lesser quantities. Without consulting your doctor, do not reduce the dosage or stop taking this drug. Sudden discontinuation of chlordiazepoxide can make your situation worse and result in withdrawal symptoms that could last anywhere from a few weeks to over a year. Your chlordiazepoxide dosage will probably be gradually reduced by your doctor. If you encounter any of the following symptoms, call your doctor or seek emergency medical attention: Unusual movements, ringing in the ears, anxiety, memory issues, difficulty concentrating, sleep issues, seizures, shaking, muscle twitching, changes in mental health, depression, burning or prickling sensations in the hands, arms, legs, or feet, thoughts of harming or killing yourself or others, excessive excitement, or losing touch with reality are some of the symptoms that can accompany these conditions.

Why is this medication prescribed?

Chlordiazepoxide is used to calm agitation brought on by alcohol withdrawal and to reduce anxiety. Chlordiazepoxide belongs to the group of drugs known as benzodiazepines. It functions by reducing the brain’s aberrant electrical activity.

How should this medicine be used?

Chlordiazepoxide is available as an oral tablet and capsule. With or without food, it is often taken once to four times each day. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Exactly as prescribed, take chlordiazepoxide.

Other uses for this medicine

Irritable bowel syndrome can also be treated with chlordiazepoxide. Discuss the potential dangers of using this medicine for your illness with your doctor.

Ask your doctor or pharmacist for more details if you’re interested in using this drug for any other conditions.

What special precautions should I follow?

Before taking chlordiazepoxide,

  • You should let your doctor and pharmacist know if you have any allergies to any of the following: chlordiazepoxide, alprazolam (Xanax), clonazepam (Klonopin), clorazepate (Gen-Xene, Tranxene), diazepam (Diastat, Valium), estazolam, flurazepam, lorazepam (Ativan), oxazepam Request a list of the components from your pharmacist.
  • Inform your doctor and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products that you are now taking or intend to use. Incorporate any of the following: antihistamines, cimetidine (Tagamet), digoxin (Lanoxin), disulfiram (Antabuse), fluoxetine (Prozac, Sarafem, Selfemra), isoniazid (Laniazid, in Rifamate, in Rifater), ketoconazole (Nizoral), digoxin (Lanoxin), digoxin (Lanoxin), ketoconazole (Nizoral), medications for depression, seizures, Parkinson’s disease, asthma, colds, or allergies; metoprolol (Lopressor, Toprol XL, others); muscle relaxants; oral contraceptives; probenecid (Probalan, in Col-Probenecid); propranolol (Inderal, Innopran); rifampin (Rifadin, Rimactane, in Rifamate, in Rifater); sedatives; sleeping pills (Depakene). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • If you have or have had had glaucoma, seizures, lung, heart, or liver illness, let your doctor know.
  • If you are breastfeeding a child or intend to become pregnant, let your doctor know. Call your doctor right away if you become pregnant while taking chlordiazepoxide.
  • If you are 65 years of age or older, discuss the advantages and disadvantages of taking chlordiazepoxide with your doctor. Chlordiazepoxide should typically not be taken by older adults because it is neither as safe nor as effective as alternative drugs that can be used to treat the same illness.
  • You should let your doctor or dentist know if you are taking chlordiazepoxide if you are having surgery, including dental surgery.
  • You should be aware that this medicine may cause you to feel sleepy. Prior to understanding how this drug affects you, avoid using machinery or driving a car.

What should I do if I forget a dose?

You should skip the missing dose and carry on with your regular dosing regimen if you take multiple doses throughout the day. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Side effects from chlordiazepoxide are possible. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Drowsiness
  • Dizziness
  • Tiredness
  • Weakness
  • Mouth ache
  • Diarrhea
  • Uneasy stomach
  • Alterations in appetite

If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Anxiety or excitement
  • Constipation
  • Having trouble urinating
  • Often urinating
  • Distorted vision
  • Alterations in sex desire or capacity

Some adverse effects can be very harmful. Call your doctor right away or seek emergency medical assistance if you see any of the symptoms below or those in the IMPORTANT WARNING section:

  • Shuffled walking
  • Persistent, little tremor or restlessness
  • Fever
  • Breathing or swallowing challenges
  • Severely itchy skin
  • The skin or eyes turning yellow
  • Abnormal heartbeat

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Store it away from excessive heat and moisture at room temperature (not in the bathroom).

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning. http://www.upandaway.org

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at http://goo.gl/c4Rm4p for additional information.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your doctor’s appointments.

Using the Gravindex pregnancy test can produce erroneous results if chlordiazepoxide is present.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • A-poxide®
  • Chlordiazachel®
  • H-Tran®
  • Librelease®
  • Libritabs®
  • Librium®
  • Lygen®
  • Mitran®
  • Poxi®
  • Librax® (as a combination product containing Clidinium, Chlordiazepoxide)
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