Why is this medication prescribed?

Ublituximab-xiiy injection is used to treat adults with various forms of multiple sclerosis (MS; a disease in which the nerves do not function properly and people may experience weakness, numbness, loss of muscle coordination, and problems with vision, speech, and bladder control), including :

• Clinically isolated syndrome (first episode of neurologic symptoms)
• Relapsing-remitting forms (course of disease where symptoms flare up from time to time)
• Secondary progressive forms (course of disease where relapses occur more often).

Ublituximab-xiiy injection is in a class of medications called monoclonal antibodies. It works by decreasing the action of immune cells that may cause nerve damage.

How should this medicine be used?

The injection known as ubituximab-xiiy is administered intravenously (into a vein) by a physician or nurse at a hospital or doctor’s office. It is a solution (liquid). The initial infusion takes place over four hours, and then two weeks later, a second infusion takes place over an hour. After that, the subsequent infusions take place over an hour every twenty-four weeks. The first hour following your infusion, your doctor will keep an eye on you. Injections of ubituximab-xiiy assist manage multiple sclerosis, but they do not treat the disease.

Other uses for this medicine

Ask your doctor or pharmacist for more information if you think this medicine could be recommended for something else.

What special precautions should I follow?

Special precautions should be observed when using ublituximab-xiiy injection. Some of these precautions include:

• If you have an allergy to any of the ingredients in ublituximab-xiiy injection, any other medications, or ublituximab-xiiy itself, let your doctor and pharmacist know. For an ingredient list, consult the Medication Guide or ask your pharmacist.
• Inform your physician and pharmacist about all of the vitamins, dietary supplements, herbal remedies, and prescription and over-the-counter drugs you currently take or intend to use while receiving ublituximab-xiiy. Your doctor might need to carefully monitor you for any negative effects or adjust the dosages of your medications.
• Inform your physician whether you now have or have ever had hepatitis B virus (HBV) infection. You could be advised by your physician not to take ublituximab-xiiy.
• Consult your physician to determine whether you require any immunizations prior to receiving ublituximab-xiiy. Inform your physician if you have had a vaccination in the last four weeks. Throughout your therapy, avoid becoming immunized without first consulting your doctor.
• Inform your physician if you are nursing a baby, intend to get pregnant, or are already pregnant. If you are a female, you must use birth control during your therapy and for six months following your last dose, as well as take a pregnancy test before beginning treatment. Consult your physician about the many birth control options available to you at this time to avoid getting pregnant. Inform your doctor right away if you become pregnant while taking ublituximab-xiiy injections. The fetus may suffer from ubituximab-xiiy.

Always follow your healthcare provider’s instructions and read the medication guide included with ubituximab-xiiy for detailed information on precautions, warnings, and potential interactions. If you have any concerns or questions about using ubituximab-xiiy, consult your doctor or pharmacist for guidance.

What special dietary instructions should I follow?

• There are typically no specific dietary restrictions associated with Ublituximab-xiiy. However, maintaining a healthy and balanced diet is important for overall well-being, especially if you have a condition like multiple sclerosis.
• If you have any dietary concerns or restrictions, discuss them with your healthcare provider or a registered dietitian who can provide personalized guidance.

What should I do if I forget a dose?

• If you miss a dose of Ublituximab-xiiy, contact your healthcare provider or infusion center as soon as possible to reschedule the missed dose.
• It’s essential to follow the dosing schedule prescribed by your doctor to ensure the medication’s effectiveness.
• Avoid doubling up on doses unless specifically instructed by your healthcare provider.

What side effects can this medication cause?

Brisdelle, containing paroxetine, may cause various side effects, although not everyone experiences them. Common side effects of Brisdelle may include:

• Pain in arms or legs
• Difficulty sleeping
• Tiredness

In addition to these common side effects, ubituximab-xiiymay also cause more serious adverse reactions in some individuals. These include:

• Fever, chills, headache, flu-like symptoms, fast heartbeat, hives, itchy skin, dizziness, feeling faint, tongue or throat swelling, redness of the skin
• Cough, chest pain, wheezing, throat irritation, trouble breathing
• Nausea, abdominal pain
• Difficulty or pain while urinating, lower back pain
• Weakness on one side of the body, loss of coordination, vision problems, confusion, memory impairment, personality changes

There could be more side effects with ubituximab-xiiy. If you have any odd side effects while taking this medicine, contact your doctor.

Keep in mind that this list is not exhaustive, and individual experiences with Ublituximab-xiiy may vary. Always consult your healthcare provider if you have any concerns about side effects or if you experience any unexpected symptoms while taking this medication.

What should I know about storage and disposal of this medication?

Storage and Disposal:

• • Ublituximab-xiiy is typically provided in a healthcare setting, such as an infusion center or hospital, and is administered by healthcare professionals. Therefore, storage is usually handled by the facility where the medication is administered.
  • If you are provided with Ublituximab-xiiy for home use, your healthcare provider will give you specific instructions on how to store it properly. Generally, it should be stored according to the manufacturer’s recommendations, typically in a refrigerator at a controlled temperature.
  • Do not freeze Ublituximab-xiiy, and protect it from light.
  • Follow your healthcare provider’s instructions on how to properly dispose of any unused or expired medication. This may involve returning it to the healthcare facility for proper disposal or following local regulations for medication disposal.

In case of emergency/overdose

In case of an emergency or overdose involving Ublituximab-xiiy injection, seek immediate medical attention or contact your local poison control center. Be prepared to provide information such as the amount of medication taken, when it was taken, and any symptoms experienced.

What other information should I know?

• Other Information: Before using Ublituximab-xiiy injections, inform your healthcare provider about any allergies you may have, other medications you are taking (including prescription, over-the-counter, vitamins, and herbal supplements), and any medical conditions you have. Your healthcare provider will determine the appropriate dosage and administration schedule for you based on your individual needs.
• Administration: Ublituximab-xiiy injections are typically administered by a healthcare professional in a clinical setting, such as a hospital or infusion center. Follow your healthcare provider’s instructions regarding the administration of this medication.
• Side Effects: Like all medications, Ublituximab-xiiy injections may cause side effects. Common side effects may include infusion reactions (such as fever, chills, nausea, and headache), infections, low blood cell counts, and fatigue. Contact your healthcare provider if you experience any side effects or if they become severe or persistent.

Always consult your healthcare provider or pharmacist if you have any questions or concerns about the storage, disposal, administration, or side effects of Ublituximab-xiiy injections.