WARNING

While Vasotec (enalapril) is generally considered safe and effective when used under the supervision of a healthcare professional, like any medication, it carries potential risks and side effects. It’s important to be aware of these risks and discuss them with your doctor before starting the medication. Here are some potential risks associated with taking Vasotec:

• Low Blood Pressure (Hypotension): Enalapril can cause a decrease in blood pressure, especially when starting the medication or increasing the dosage. This can lead to dizziness or fainting, particularly when standing up quickly.
• Kidney Impairment: In some cases, ACE inhibitors like Vasotec can affect kidney function. Your doctor will likely monitor your kidney function through blood tests.
• Hyperkalemia (High Potassium Levels): Vasotec may lead to an increase in potassium levels in the blood. Elevated potassium levels can be dangerous and may cause irregular heartbeats or other complications.
• Cough: ACE inhibitors, including Vasotec, are associated with a persistent dry cough in some people. If you experience this side effect, notify your doctor.
• Angioedema: Although rare, ACE inhibitors can cause a serious swelling of deeper layers of the skin, often around the eyes and lips. This condition, known as angioedema, requires immediate medical attention.
• Allergic Reactions: Some individuals may be allergic to enalapril, experiencing symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing. Seek medical help if you suspect an allergic reaction.
• Pregnancy Risk: Vasotec can harm an unborn baby during pregnancy. If you are pregnant or planning to become pregnant, discuss the risks and benefits with your doctor.
• Interaction with Other Medications: Vasotec may interact with other medications, including diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), and potassium supplements. Inform your doctor about all the medications and supplements you are taking.

It’s crucial to attend regular check-ups with your healthcare provider to monitor for potential side effects and adjust the dosage if needed. Always take Vasotec as prescribed and inform your doctor of any concerns or unusual symptoms you may experience while on the medication. Do not stop taking Vasotec or adjust the dosage without consulting your healthcare provider, as sudden discontinuation can have adverse effects.

Why is this medication prescribed?

Vasotec is a brand name for the medication enalapril, which belongs to a class of drugs known as angiotensin-converting enzyme (ACE) inhibitors. It is commonly prescribed for the treatment of high blood pressure (hypertension), heart failure, and certain types of chronic kidney diseases.

• High Blood Pressure (Hypertension): Vasotec helps to relax blood vessels, reducing blood pressure. This can lower the risk of strokes, heart attacks, and other cardiovascular events.
• Heart Failure: For individuals with heart failure, Vasotec can help the heart pump more effectively by reducing the workload on the heart and improving its overall function.
• Chronic Kidney Diseases: Vasotec may also be prescribed to manage certain types of chronic kidney diseases, particularly those related to diabetes.

How should this medicine be used?

Here are some general guidelines for using Vasotec:

• Dosage: The dosage of Vasotec varies depending on the individual’s condition and response to the medication. It is essential to take the medication exactly as prescribed by your doctor.
• Administration: Vasotec is typically taken orally, with or without food. The tablets are usually taken once or twice a day.
• Follow Doctor’s Instructions: Always follow your doctor’s instructions regarding the dosage and frequency of administration. Do not alter your dose or stop taking the medication without consulting your healthcare provider.
• Regular Monitoring: Your doctor may monitor your blood pressure and kidney function regularly while you are on Vasotec to ensure that the medication is working effectively and not causing any adverse effects.
• Missed Dose: If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double up on doses to make up for a missed one.
• Precautions: Inform your doctor about any other medications, supplements, or medical conditions you have, as certain drugs or conditions may interact with Vasotec.
• Side Effects: Be aware of potential side effects and contact your healthcare provider if you experience any unusual symptoms.

It’s crucial to work closely with your healthcare provider to ensure the safe and effective use of Vasotec, and to discuss any concerns or questions you may have about the medication.

Other uses for this medicine

Vasotec (enalapril) might also be used for other medical conditions under the guidance of a healthcare professional. Some potential off-label uses include:

• Diabetic Nephropathy: Enalapril may be used to manage kidney complications associated with diabetes.
• Left Ventricular Dysfunction: It might be prescribed for individuals with asymptomatic left ventricular dysfunction.
• Prevention of Cardiovascular Events: In some cases, Vasotec may be considered for preventing cardiovascular events in individuals at high risk.

What special precautions should I follow?

Special Precautions for Vasotec (Enalapril):

• Pregnancy and Breastfeeding: Vasotec can harm the unborn baby during pregnancy and may pass into breast milk. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits with your doctor.
• Allergies: Inform your doctor if you have a history of allergies to enalapril or other ACE inhibitors.
• Kidney Problems: If you have kidney problems or are on dialysis, your doctor may adjust the dosage of Vasotec or monitor you more closely.
• Liver Problems: Inform your healthcare provider if you have liver disease, as dosage adjustments may be necessary.
• Salt/Volume Depletion: Dehydration, excessive sweating, severe diarrhea, or vomiting may lead to a drop in blood pressure. Make sure your doctor is aware of these conditions.
• High Potassium Levels: Discuss with your doctor if you are taking potassium supplements, salt substitutes containing potassium, or medications that increase potassium levels.
• Diabetes: Enalapril can affect blood sugar levels. If you have diabetes, monitor your blood sugar levels regularly and inform your doctor of any changes.
• Surgery/Anesthesia: If you are scheduled for surgery or anesthesia, inform the healthcare professionals involved that you are taking Vasotec.
• Angioedema: If you have a history of angioedema (swelling of deeper layers of the skin), discuss it with your doctor.
• Cough: While a persistent dry cough is a less common side effect, inform your doctor if you experience it.

Always disclose your complete medical history and any medications or supplements you are taking to your healthcare provider to ensure safe and effective use of Vasotec. Follow your doctor’s instructions carefully, attend regular check-ups, and report any unusual symptoms promptly.

What special dietary instructions should I follow?

There may not be specific dietary restrictions associated with quizartinib. However, it’s crucial to maintain a healthy and balanced diet. If you have any concerns about your diet, discuss them with your healthcare provider or a registered dietitian.

What should I do if I forget a dose?

If you forget to take a dose of quizartinib, contact your healthcare provider immediately for guidance. They will advise you on the best course of action, which may include taking the missed dose as soon as you remember or skipping it and returning to your regular dosing schedule.

What side effects can this medication cause?

Vasotec (enalapril) can cause various side effects, and it’s important to be aware of them and promptly report any unusual symptoms to your healthcare provider. Common side effects are generally mild, but some may be serious. Not everyone will experience these side effects, and the severity can vary. Common and serious side effects of Vasotec include:

Common Side Effects:

• Dizziness or Lightheadedness: This may occur, especially when standing up quickly. It’s advisable to rise slowly from a sitting or lying position.
• Cough: A persistent dry cough is a known side effect of ACE inhibitors, including Vasotec. If you experience this, inform your doctor.
• Fatigue or Weakness: Some people may experience tiredness or weakness while taking Vasotec.

Serious Side Effects (Seek Immediate Medical Attention):

• Swelling of Face, Lips, Tongue, or Throat (Angioedema): This is a rare but serious side effect. Seek emergency medical attention if you notice sudden swelling, difficulty breathing, or swallowing.
• Severe Allergic Reactions: Allergic reactions can include rash, itching, severe dizziness, or trouble breathing. Seek emergency medical attention if you experience these symptoms.
• Low Blood Pressure (Hypotension): This can cause symptoms such as fainting, especially when standing up quickly.
• Kidney Problems: Changes in kidney function may occur. Your doctor will monitor your kidney function through blood tests.
• High Potassium Levels (Hyperkalemia): This can lead to symptoms such as irregular heartbeats. Inform your doctor if you experience palpitations or other cardiac symptoms.
• Changes in Blood Cell Counts: Vasotec can affect blood cell counts, and your doctor may monitor this through regular blood tests.
• Liver Problems: In rare cases, liver problems may occur. Inform your healthcare provider if you experience symptoms such as yellowing of the eyes or skin (jaundice) or persistent nausea.

It’s important to note that this list is not exhaustive, and individual responses to medication can vary. Always discuss any concerns or symptoms with your healthcare provider. If you experience severe or life-threatening symptoms, seek emergency medical attention immediately. Your doctor can provide guidance on managing side effects or may adjust your medication if necessary.

What should I know about storage and disposal of this medication?

Storage and Disposal of Vasotec (Enalapril):

• Storage:
  • Keep Vasotec (enalapril) in its original packaging or container.
  • Store at room temperature, away from moisture and heat.
  • Avoid exposure to excessive humidity.
• Disposal:
  • Dispose of unused or expired medication properly.
  • Do not flush medications down the toilet or pour them into drains unless instructed to do so.
  • Consult with your pharmacist or local waste disposal company for guidelines on proper disposal.

In case of emergency/overdose

If you suspect an overdose or experience severe symptoms, seek emergency medical attention. Overdose symptoms may include:

• Extreme dizziness or fainting
• Weakness
• Rapid or irregular heartbeat
• Severe hypotension (very low blood pressure)

What other information should I know?

• Regular Check-ups: Attend regular check-ups with your healthcare provider to monitor your response to Vasotec and assess for any potential side effects.
• Blood Pressure Monitoring: Regularly monitor your blood pressure at home if advised by your doctor.
• Lab Tests: Your doctor may order periodic blood tests to check kidney function, electrolyte levels, and other parameters.
• Inform Healthcare Providers: Inform all healthcare providers (doctors, dentists, and pharmacists) about your use of Vasotec before undergoing any medical procedures or starting new medications.
• Avoid Alcohol: Limit alcohol consumption, as it can enhance the blood pressure-lowering effects of Vasotec.
• Limit Salt Intake: Follow any dietary recommendations provided by your doctor, including limits on salt intake.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss this with your doctor.
• Interactions: Inform your healthcare provider about all medications, supplements, and herbal products you are taking to avoid potential interactions.
• Symptoms to Report: Report any unusual symptoms, side effects, or changes in health to your healthcare provider promptly.
• Follow Doctor’s Instructions: Take Vasotec exactly as prescribed by your doctor. Do not change the dosage without consulting your healthcare provider.

Always consult with your healthcare provider or pharmacist if you have specific questions about the storage, disposal, or usage of Vasotec. They can provide personalized guidance based on your medical history and the specific details of your prescription.