Why is this medication prescribed?

Elacestrant is a medication that falls under the category of selective estrogen receptor degraders (SERDs). It is prescribed for the treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) advanced or metastatic breast cancer in postmenopausal women who have previously received endocrine therapy.

How should this medicine be used?

Here’s how Elacestrant is typically used:

• Dosage: The dosage of Elacestrant can vary depending on factors such as the patient’s overall health, the stage of breast cancer, and any other medications they may be taking. It’s important to follow the dosage instructions provided by the prescribing healthcare professional.
• Administration: Elacestrant is usually administered orally in the form of tablets.
• Schedule: Typically, Elacestrant is taken once daily with or without food. It’s important to take it at the same time each day to maintain consistent levels of the medication in the bloodstream.
• Duration: Treatment with Elacestrant may continue as long as it is providing benefit to the patient and they are tolerating it well. The healthcare provider will monitor the patient’s response to the medication and may adjust the dosage or discontinue treatment if necessary.
• Follow-up: Regular follow-up appointments with the healthcare provider are essential to monitor the effectiveness of Elacestrant and to manage any potential side effects.
• Compliance: It’s crucial for patients to take Elacestrant exactly as prescribed by their healthcare provider. Missing doses or taking more than the prescribed amount can affect the effectiveness of the treatment.
• Storage: Elacestrant should be stored at room temperature away from moisture and heat. It’s essential to keep it out of reach of children and pets.

It’s important for patients to discuss any questions or concerns they have about Elacestrant with their healthcare provider, including potential side effects, drug interactions, and overall treatment goals.

Other uses for this medicine

While Elacestrant is primarily used for the treatment of advanced breast cancer as mentioned above, clinical trials and research may explore its potential uses in other cancer types or stages. However, as of my last update, its primary approved use is for advanced breast cancer.

What special precautions should I follow?

As for special precautions to follow when taking Elacestrant, here are some important points:

• Pregnancy and breastfeeding: Elacestrant can cause harm to an unborn baby if taken during pregnancy. Therefore, it’s crucial for women of childbearing potential to use effective contraception during treatment and for a certain period afterward. Additionally, breastfeeding should be avoided while taking Elacestrant.
• Liver function: Elacestrant may affect liver function, so regular monitoring of liver enzymes may be necessary during treatment. Patients with pre-existing liver conditions may require closer monitoring.
• Bone health: Some medications used for breast cancer treatment can weaken bones. Healthcare providers may monitor bone health and recommend supplements or other interventions as needed.
• Drug interactions: Elacestrant may interact with other medications, including herbal supplements and over-the-counter drugs. It’s essential to inform your healthcare provider about all medications and supplements you are taking to avoid potential interactions.
• Allergies: Patients with known allergies or hypersensitivity to Elacestrant or any of its components should not take the medication.
• Side effects: Like all medications, Elacestrant may cause side effects. Common side effects include fatigue, nausea, decreased appetite, diarrhea, and hot flashes. It’s essential to report any side effects to your healthcare provider promptly.
• Medical history: Before starting Elacestrant, patients should inform their healthcare provider about their complete medical history, including any pre-existing conditions or previous treatments.
• Regular monitoring: Patients taking Elacestrant may require regular monitoring of their overall health and treatment response. This may include blood tests, imaging scans, and other assessments as determined by the healthcare provider.

It’s crucial for patients to follow their healthcare provider’s instructions closely when taking Elacestrant and to report any concerns or adverse effects promptly.

What special dietary instructions should I follow?

Regarding special dietary instructions for Elacestrant, there are no specific dietary restrictions associated with this medication. However, maintaining a healthy and balanced diet is generally recommended for overall health and well-being during cancer treatment.

What should I do if I forget a dose?

If you forget to take a dose of Elacestrant, take it as soon as you remember, unless it’s almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you’re unsure about what to do, consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Elacestrant, like any medication, can cause side effects. Common side effects reported in clinical trials and experienced by patients taking Elacestrant include:

• Fatigue: Feeling unusually tired or lacking energy.
• Nausea: Feeling the urge to vomit or experiencing discomfort in the stomach.
• Decreased appetite: Having a reduced desire to eat.
• Diarrhea: Frequent, loose, or watery stools.
• Hot flashes: Sudden feelings of warmth, often accompanied by sweating and flushing of the skin.
• Headache: Pain or discomfort in the head, ranging from mild to severe.
• Vomiting: The act of forcefully expelling the contents of the stomach through the mouth.
• Muscle and joint pain: Discomfort or soreness in muscles and/or joints.
• Constipation: Difficulty passing stools or infrequent bowel movements.
• Urinary tract infections: Infections affecting the urinary system, such as the bladder or kidneys.
• Cough: A sudden expulsion of air from the lungs, often due to irritation or infection.
• Upper respiratory tract infections: Infections affecting the nose, throat, sinuses, or other parts of the upper respiratory system.
• Back pain: Discomfort or soreness in the back, ranging from mild to severe.

It’s important to note that not all individuals will experience these side effects, and some may experience different or more severe side effects. Additionally, not all side effects are listed here. If you experience any unusual or bothersome symptoms while taking Elacestrant, it’s essential to notify your healthcare provider promptly. They can provide guidance on managing side effects and adjust your treatment plan if necessary.

What should I know about storage and disposal of this medication?

Storage and Disposal:

• Storage: Store Elacestrant at room temperature, away from moisture and heat. Keep it in its original container, tightly closed, and out of reach of children and pets.
• Disposal: Dispose of unused or expired Elacestrant properly according to local regulations or guidelines. Do not flush medications down the toilet or pour them down the drain unless instructed to do so. Consult your pharmacist or local waste disposal authority for guidance on the proper disposal of medications.

In case of emergency/overdose

• In case of emergency: If you experience severe or life-threatening symptoms while taking Elacestrant, such as difficulty breathing, severe allergic reactions, or signs of an overdose, seek immediate medical attention by calling emergency services or visiting the nearest emergency room.
• Overdose: If you suspect an overdose of Elacestrant, contact your healthcare provider, poison control center, or emergency room immediately. Overdose symptoms may include severe nausea, vomiting, dizziness, fainting, or other serious side effects.

What other information should I know?

• Follow-up appointments: Attend all scheduled follow-up appointments with your healthcare provider while taking Elacestrant. Regular monitoring is essential to evaluate treatment response, manage side effects, and adjust the treatment plan as needed.
• Blood tests: Your healthcare provider may order periodic blood tests to monitor your liver function and other parameters during treatment with Elacestrant.
• Drug interactions: Inform your healthcare provider about all medications, supplements, and herbal products you are taking before starting Elacestrant to avoid potential drug interactions.
• Missed doses: If you miss a dose of Elacestrant, take it as soon as you remember unless it’s almost time for your next dose. Do not double the dose to catch up. Follow your regular dosing schedule.
• Patient education: Make sure you understand how to take Elacestrant correctly, including dosage instructions, possible side effects, and precautions. Ask your healthcare provider or pharmacist if you have any questions or concerns.
• Storage conditions: Protect Elacestrant from light and moisture. Keep it in its original container with the lid tightly closed.
• Pregnancy and breastfeeding: Avoid becoming pregnant while taking Elacestrant and do not breastfeed during treatment, as it may harm the baby.
• Driving and operating machinery: Elacestrant may cause dizziness or fatigue in some individuals. If you experience these effects, avoid driving or operating heavy machinery until you know how the medication affects you.

Always consult your healthcare provider or pharmacist if you have any questions or concerns about taking Elacestrant or any other medication. They can provide personalized advice and guidance based on your individual medical history and circumstances.