Why is this medication prescribed?

Clenpiq is a medication prescribed for bowel preparation before colonoscopy, a procedure that allows doctors to examine the inside of the colon (large intestine). It is used to cleanse the colon by causing diarrhea, which helps clear the colon of stool and allows for better visualization during the procedure.

How should this medicine be used?

Here’s how Clenpiq should typically be used:

• Preparation: Follow the specific instructions provided by your healthcare provider. Generally, you will start preparing the day before your colonoscopy.
• Dosing: Clenpiq is usually taken in divided doses. You will be instructed on when to start taking it and how much to take at each interval.
• Mixing: Clenpiq comes as a powder that you must mix with water before drinking. You will need to add water to the fill line marked on the bottle.
• Drinking: After mixing, drink the entire solution within a specific time frame as directed by your doctor. It is important to drink plenty of clear liquids (such as water, clear broth, or plain tea or coffee without milk) before, during, and after taking Clenpiq to prevent dehydration.
• Timing: The timing of when you take Clenpiq is crucial for effective bowel cleansing. Follow your healthcare provider’s instructions carefully regarding when to start and complete the preparation.
• Follow-up: Ensure you complete the entire course of Clenpiq as prescribed. Your healthcare provider will give you specific guidelines on when to stop consuming solid foods and when to start and stop consuming clear liquids.

It’s essential to follow all instructions provided by your doctor or healthcare provider to ensure that the colon is thoroughly cleansed for the colonoscopy. If you have any questions about how to use Clenpiq, be sure to ask your healthcare provider for clarification.

Other uses for this medicine

Clenpiq (sodium picosulfate, magnesium oxide, and anhydrous citric acid) is primarily used for bowel preparation before colonoscopy to cleanse the colon. It is not typically used for other medical conditions or purposes.

What special precautions should I follow?

There are some special precautions to be aware of when using Clenpiq:

• Allergies: Inform your healthcare provider if you are allergic to any of the ingredients in Clenpiq or if you have had allergic reactions to other laxatives in the past.
• Medical Conditions: Let your healthcare provider know about any medical conditions you have, especially if you have:
  • Kidney problems
  • Heart problems
  • Electrolyte imbalances
  • Gastrointestinal disorders
  • Swallowing problems
  • History of seizures
• Medications: Inform your healthcare provider about all prescription and over-the-counter medications, vitamins, and herbal supplements you are taking. Some medications may interact with Clenpiq, affecting how it works or increasing the risk of side effects.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Clenpiq with your healthcare provider.
• Fluid Intake: It is crucial to drink plenty of clear liquids before, during, and after taking Clenpiq to prevent dehydration and electrolyte imbalances. Follow your healthcare provider’s instructions regarding the amount and types of fluids you can consume.
• Side Effects: Be aware of potential side effects of Clenpiq, including nausea, vomiting, abdominal pain, bloating, and electrolyte disturbances. Contact your healthcare provider if you experience severe or persistent symptoms.
• Driving and Operating Machinery: Clenpiq can cause dizziness or drowsiness. Avoid driving or operating machinery until you know how Clenpiq affects you.
• Follow Instructions Carefully: Follow the specific dosing and timing instructions provided by your healthcare provider to ensure effective bowel cleansing.

Always consult your healthcare provider or pharmacist if you have any questions or concerns about using Clenpiq. It is important to use this medication exactly as directed for safe and effective colonoscopy preparation.

What special dietary instructions should I follow?

• Clear Liquid Diet: Follow a clear liquid diet before and after taking Clenpiq as directed by your healthcare provider. Clear liquids include water, clear broth, plain tea or coffee (without milk), sports drinks without red or purple dye, and clear fruit juices without pulp.
• Avoid Certain Foods: Avoid solid foods, dairy products, and liquids that are not clear (like milk, orange juice with pulp, and liquids with red or purple dye) during the bowel preparation process.
• Timing of Intake: Follow the specific timing instructions for taking Clenpiq and consuming clear liquids provided by your healthcare provider.

What should I do if I forget a dose?

If you forget to take a dose of Clenpiq, contact your healthcare provider or follow their specific instructions. It is important to follow the prescribed schedule to ensure adequate bowel cleansing for the colonoscopy.

Generally, missing a dose or not following the exact timing may affect the effectiveness of the bowel preparation. Your healthcare provider may advise adjusting the timing of subsequent doses or other instructions to ensure proper preparation.

What side effects can this medication cause?

Clenpiq, like any medication, can cause side effects. Common side effects include:

• Nausea and Vomiting: These are the most frequently reported side effects with Clenpiq. Nausea can occur during or after taking the medication.
• Abdominal Pain or Discomfort: Some people may experience abdominal cramping, bloating, or discomfort.
• Diarrhea: Clenpiq is intended to induce diarrhea as part of bowel preparation for colonoscopy. This is a desired effect but can be uncomfortable.
• Headache: Headaches are another common side effect reported by some individuals.
• Dizziness: Clenpiq can cause dizziness or lightheadedness, which may affect balance or coordination.
• Electrolyte Imbalances: In some cases, Clenpiq can lead to electrolyte disturbances, such as low potassium levels (hypokalemia) or low sodium levels (hyponatremia). These can cause symptoms like muscle weakness, irregular heartbeat, or confusion.
• Dehydration: Diarrhea induced by Clenpiq can lead to dehydration if adequate fluids are not consumed.
• Allergic Reactions: Although rare, allergic reactions to Clenpiq can occur. Symptoms may include rash, itching, swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.
• Other Gastrointestinal Issues: Less commonly, individuals may experience flatulence (gas), vomiting, or anal irritation.

It’s essential to follow your healthcare provider’s instructions carefully when taking Clenpiq to minimize the risk of side effects and ensure effective bowel preparation. If you experience severe or persistent side effects, contact your healthcare provider promptly.

What should I know about storage and disposal of this medication?

Storage and Disposal of Clenpiq:

• Storage: Store Clenpiq at room temperature between 20°C to 25°C (68°F to 77°F). Keep the bottle tightly closed and protect it from light.
• Keep Out of Reach: Store Clenpiq out of reach of children and pets to prevent accidental ingestion.
• Disposal: Dispose of unused Clenpiq solution according to local regulations or guidelines. Do not flush unused medication down the toilet or pour it into a drain unless instructed to do so. Proper disposal helps prevent environmental contamination.

In case of emergency/overdose

• Symptoms: In case of an overdose or emergency, such as severe diarrhea, dehydration, electrolyte imbalance (e.g., muscle weakness, irregular heartbeat), or allergic reaction (e.g., severe rash, difficulty breathing), seek immediate medical attention.
• Poison Control: If you suspect an overdose or accidental ingestion, contact your local poison control center (in the US, call 1-800-222-1222) or go to the nearest emergency room.

What other information should I know?

• Effectiveness: Clenpiq is used for bowel preparation before a colonoscopy to cleanse the colon. Proper bowel preparation is crucial for the success of the procedure.
• Clear Liquid Diet: Follow your healthcare provider’s instructions regarding the clear liquid diet before and after taking Clenpiq.
• Monitoring: Your healthcare provider may monitor your electrolyte levels and overall health during and after using Clenpiq to ensure safety.
• Medical History: Inform your healthcare provider about any medical conditions, allergies, medications (including over-the-counter drugs and supplements), and pregnancy or breastfeeding status before using Clenpiq.
• Follow Instructions: Always follow the dosing schedule, mixing instructions, and clear liquid consumption guidelines provided by your healthcare provider for Clenpiq to be effective.
• Travel: If you need to travel for your colonoscopy after taking Clenpiq, plan accordingly for access to restroom facilities and continued clear liquid consumption.
• Side Effects: Be aware of potential side effects (such as nausea, vomiting, abdominal pain, headache) and contact your healthcare provider if they are severe or persistent.

Following these guidelines will help ensure safe and effective use of Clenpiq for your colonoscopy preparation. If you have any questions or concerns about Clenpiq, consult your healthcare provider or pharmacist for clarification.