Why is this medication prescribed?

Ajovy (fremanezumab) is prescribed for the prevention of migraine headaches. It’s a medication used for adults who experience migraines frequently, typically defined as 4 or more migraine days per month. Ajovy is a type of medication known as a CGRP inhibitor, which works by blocking a protein involved in migraine attacks. It’s often used when other preventive treatments have not been effective or are not well tolerated.

How should this medicine be used?

Ajovy is typically administered as an injection. Here’s a general overview of how it’s used:

• Dosage and Frequency:
  • For Monthly Dosing: The recommended dose is 225 mg injected subcutaneously once a month.
  • For Quarterly Dosing: An alternative is 675 mg injected subcutaneously once every three months.
• Administration: Ajovy is usually injected into the abdomen, thigh, or upper arm. It can be administered by a healthcare provider or, in some cases, by the patient themselves after proper training.
• Preparation: The injection site should be clean and dry. Ajovy is available in pre-filled syringes or autoinjectors.
• Storage: Store Ajovy in the refrigerator at 36°F to 46°F (2°C to 8°C). Do not freeze. If needed, it can be stored at room temperature (up to 77°F or 25°C) for up to 7 days before use.
• Usage Tips: Follow the specific instructions provided by your healthcare provider or on the medication label. If you miss a dose, contact your healthcare provider for guidance on how to proceed.

Always consult your healthcare provider for personalized instructions and to ensure Ajovy is used correctly for your specific situation.

Other uses for this medicine

Ajovy (fremanezumab) is primarily used for migraine prevention, but it’s not typically used for other conditions. Its use for migraines is supported by evidence, but off-label uses would be considered unproven or experimental.

What special precautions should I follow?

Regarding special precautions, here are some important considerations:

• Allergic Reactions: Be aware of any signs of allergic reactions, such as rash, itching, swelling, severe dizziness, or trouble breathing. If these occur, seek medical help immediately.
• Pregnancy and Breastfeeding: There’s limited information about Ajovy’s safety during pregnancy or breastfeeding. Discuss with your healthcare provider if you’re pregnant, planning to become pregnant, or breastfeeding.
• Other Medications: Inform your healthcare provider about all other medications you are taking, including over-the-counter drugs and supplements, to avoid potential interactions.
• Medical Conditions: Inform your provider if you have a history of severe allergic reactions, as this could affect your suitability for Ajovy.
• Injection Site Reactions: Some people may experience reactions at the injection site, such as redness, pain, or swelling. Report these to your healthcare provider if they persist or worsen.

Always follow your healthcare provider’s instructions and consult them with any concerns or questions regarding Ajovy’s use and precautions.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Ajovy. However, maintaining a healthy diet may help with overall migraine management. If you have specific dietary concerns or triggers for your migraines, discuss them with your healthcare provider.

What should I do if I forget a dose?

• Monthly Dosing: If you miss a dose of Ajovy (225 mg), administer it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and return to your regular schedule. Do not double up on doses.
• Quarterly Dosing: If you miss a dose of Ajovy (675 mg), contact your healthcare provider for guidance on when to take the missed dose or to reschedule your next dose.

What side effects can this medication cause?

Ajovy (fremanezumab) can cause side effects, although not everyone experiences them. Common side effects include:

• Injection Site Reactions: Redness, pain, or swelling at the injection site are common and usually mild.
• Headache: Some individuals might experience headaches, which can be a side effect or related to the underlying migraine condition.
• Allergic Reactions: Rarely, Ajovy can cause allergic reactions, including rash, itching, swelling, or severe dizziness.
• Gastrointestinal Symptoms: Some people might experience nausea or other gastrointestinal discomforts.
• Fatigue: Feeling tired or fatigued can occur but is less common.

Most side effects are mild and may resolve on their own. However, if you experience any severe or persistent symptoms, or if you have signs of an allergic reaction, contact your healthcare provider immediately.

What should I know about storage and disposal of this medication?

Storage and Disposal of Ajovy:

Storage of Ajovy:

• Store Ajovy in the refrigerator at 36°F to 46°F (2°C to 8°C). Do not freeze the medication.
• If needed, Ajovy can be stored at room temperature (up to 77°F or 25°C) for up to 7 days before use.
• Keep Ajovy in its original carton to protect it from light until you’re ready to use it.
• After taking the medication out of the refrigerator, if it is not used immediately, return it to the refrigerator or discard it if it has been at room temperature for more than 7 days.

Disposal of Ajovy:

• Follow your healthcare provider’s or pharmacist’s instructions for proper disposal. Some areas have medication take-back programs for safe disposal. Do not throw Ajovy in the household trash or flush it down the toilet unless specifically instructed.

In case of emergency/overdose

• Emergency: If you suspect an allergic reaction or any severe side effects, seek medical attention immediately.
• Overdose: While specific overdose information for Ajovy is limited, contact your healthcare provider or local poison control center for guidance if you think you may have used too much of the medication.

What other information should I know?

• Regular Check-ins: Keep regular appointments with your healthcare provider to monitor the effectiveness and any side effects of Ajovy.
• Medication Records: Maintain a record of your doses and any side effects you experience, and share this information with your healthcare provider.
• Avoid Missed Doses: Try to administer Ajovy on schedule to maintain its effectiveness in preventing migraines.

Always follow your healthcare provider’s instructions and consult them with any specific questions or concerns related to Ajovy.