WARNING

Here’s a detailed look at the risks associated with taking Aveed (generic testosterone enanthate), considering it’s an intramuscular injection:

• Increased Risk of Heart Attack and Stroke: Long-term testosterone therapy can potentially increase the risk of heart-related issues, including heart attacks and strokes, particularly in individuals with pre-existing cardiovascular conditions.
• High Blood Pressure: Testosterone can lead to elevated blood pressure, which may require monitoring and management.
• Liver Toxicity: Although testosterone enanthate is generally less likely to cause liver issues compared to oral testosterone formulations, there is still a potential risk of liver damage. Monitor for symptoms such as jaundice (yellowing of the skin or eyes), dark urine, or abdominal pain.
• Prostate Enlargement: Testosterone can cause or worsen benign prostatic hyperplasia (BPH), leading to urinary symptoms such as frequent urination or difficulty urinating.
• Prostate Cancer: There is a potential risk of stimulating the growth of existing prostate cancer. Regular screening and monitoring are important.
• Weight Gain: Testosterone therapy can lead to increased weight gain, particularly in the form of fluid retention and increased muscle mass.
• Changes in Lipid Profile: Testosterone can affect cholesterol levels, potentially leading to an increased risk of cardiovascular issues.
• Mood Swings: Testosterone therapy can cause mood swings, irritability, or even aggressive behavior. It may also contribute to symptoms of anxiety or depression in some individuals.
• Libido Changes: While testosterone often improves libido, in some cases, it can lead to either an increase or decrease in sexual desire.
• Erectile Dysfunction: Rarely, testosterone therapy may contribute to erectile dysfunction or changes in sexual function.
• Acne: Increased oil production can lead to acne or worsening of existing acne.
• Hair Growth: Excessive hair growth on the body or face may occur.
• Testicular Atrophy: Testosterone therapy can cause shrinkage of the testicles, which may affect fertility and sperm production.
• Reduced Fertility: Long-term use can impact sperm production and potentially lead to reduced fertility.
• Exacerbation of Sleep Apnea: Testosterone therapy can worsen sleep apnea, a condition where breathing repeatedly stops and starts during sleep.
• Gynecomastia: Enlargement of breast tissue in men can occur due to hormonal changes.
• Fluid Retention: Increased fluid retention may lead to swelling in the extremities.

Regular follow-ups with your healthcare provider are essential to monitor for these risks and manage any potential side effects. Blood tests and physical exams are typically used to assess your health and adjust treatment as needed.

If you experience any severe or concerning symptoms while on Aveed, it’s crucial to contact your healthcare provider immediately.

Why is this medication prescribed?

Aveed is prescribed primarily for testosterone replacement therapy in males with low testosterone levels due to various conditions, such as:

• Hypogonadism: A condition where the body doesn’t produce enough testosterone, leading to symptoms like low libido, fatigue, and depression.
• Delayed Puberty: In adolescents who are not developing secondary sexual characteristics at the expected age.
• Hormone Replacement Therapy: For individuals transitioning from female to male as part of gender-affirming treatment.

Testosterone therapy helps to restore normal levels of testosterone, improving symptoms and overall quality of life for those with deficiencies or imbalances.

How should this medicine be used?

Aveed is actually administered as an intramuscular injection, not topically. Here’s how it is typically used:

• Administration: Aveed is injected into the muscle (usually the buttock) by a healthcare professional. It is not intended for topical use or oral ingestion.
• Dosage Schedule: The typical dosing schedule is once every 10 weeks. Your doctor will determine the appropriate dosage and schedule based on your specific needs and response to the treatment.
• Injection Technique: The injection should be done by a trained healthcare provider to ensure proper technique and to minimize discomfort or complications.
• Monitoring: Regular follow-up appointments are necessary to monitor testosterone levels, assess response to the therapy, and adjust dosages if needed.

Always follow your healthcare provider’s instructions and consult them if you have any questions or concerns about your treatment.

Other uses for this medicine

• Hormone Replacement Therapy: For individuals undergoing gender transition (female-to-male) to develop male secondary sexual characteristics.
• Delayed Puberty: To assist boys with delayed sexual development.

What special precautions should I follow?

Special Precautions:

• Medical History: Inform your healthcare provider if you have a history of prostate cancer, breast cancer, heart disease, liver disease, or any other serious health conditions.
• Side Effects: Be aware of potential side effects, including mood changes, acne, fluid retention, and changes in libido.
• Regular Monitoring: Regular blood tests are needed to monitor testosterone levels, liver function, and other health parameters.
• Injection Site Care: Follow proper procedures for injection site care to avoid infections or complications.
• Interactions: Notify your doctor about all other medications and supplements you are taking, as testosterone can interact with other treatments.
• Pregnancy and Breastfeeding: If you are pregnant or breastfeeding, or planning to become pregnant, inform your healthcare provider, as testosterone can affect fetal development.

Always follow your healthcare provider’s guidance and discuss any concerns or questions you have about your treatment.

What special dietary instructions should I follow?

There are no specific dietary restrictions for Aveed. However, maintaining a balanced diet and staying hydrated is generally beneficial for overall health. If you have any particular dietary concerns, consult with your healthcare provider.

What should I do if I forget a dose?

If you miss a scheduled dose, contact your healthcare provider for guidance. They will provide instructions on how to reschedule your next dose. Do not attempt to self-administer a missed dose or adjust your dosing schedule without professional advice.

What side effects can this medication cause?

Aveed, as an intramuscular testosterone injection, can cause side effects. Common and potential side effects include:

Common Side Effects:

• Injection Site Reactions: Pain, swelling, or redness at the injection site.
• Acne: Increased oiliness or acne outbreaks.
• Mood Changes: Irritability, mood swings, or changes in emotional state.
• Fluid Retention: Swelling in the ankles or legs.
• Hair Changes: Increased facial or body hair growth.
• Libido Changes: Altered sex drive.

Serious Side Effects:

• Cardiovascular Issues: Increased risk of heart attack or stroke, especially with long-term use.
• Liver Problems: Symptoms of liver issues, such as jaundice (yellowing of the skin or eyes).
• Prostate Issues: Increased risk of prostate problems or cancer.
• Sleep Apnea: Worsening of sleep apnea or breathing problems during sleep.
• Mental Health Changes: Severe mood swings, depression, or anxiety.
• Gynecomastia: Enlargement of breast tissue in men.
• Testicular Atrophy: Shrinkage of the testicles.
• Elevated Red Blood Cells: Increased risk of blood clots or other related issues.

If you experience any severe or persistent side effects, contact your healthcare provider immediately. They can help manage these effects and determine whether any adjustments to your treatment are necessary.

What should I know about storage and disposal of this medication?

Storage and Disposal of Aveed (generic testosterone enanthate):

Storage:

• Store Aveed at room temperature, away from direct heat and light. Typically, this means keeping it at temperatures between 20-25°C (68-77°F).
• Do not freeze the medication.
• Keep the medication out of reach of children and pets.

Disposal:

• Do not throw away unused or expired Aveed in household trash.
• Dispose of the medication through a pharmacy take-back program or other authorized disposal sites.
• Follow local regulations for disposal of medications.

In case of emergency/overdose

• Emergency Help: If you suspect an overdose, seek emergency medical attention immediately.
• Symptoms of Overdose: While testosterone overdose is rare, symptoms might include severe headache, nausea, vomiting, or unusual mood changes.
• Contact Healthcare Provider: If you experience any severe or concerning symptoms, contact your healthcare provider right away.

What other information should I know?

• Adherence to Dosing Schedule: Follow the dosing schedule provided by your healthcare provider strictly. Skipping doses or changing the schedule can affect treatment effectiveness.
• Regular Monitoring: Attend all scheduled follow-up appointments for monitoring your response to treatment and any potential side effects.
• Communicate with Healthcare Provider: Keep open communication with your healthcare provider about any new symptoms or health concerns that arise during treatment.

Always consult your healthcare provider for any specific instructions or if you have additional questions about your treatment.