Why is this medication prescribed?

Aricept (donepezil) is prescribed primarily to treat symptoms of Alzheimer’s disease. It is used to help improve cognitive function, such as memory and reasoning skills, and to help manage symptoms related to the disease. Aricept works by increasing levels of acetylcholine, a neurotransmitter that is often low in individuals with Alzheimer’s disease, which can help with communication between nerve cells in the brain. It may also be prescribed for mild to moderate dementia caused by other conditions.

How should this medicine be used?

Aricept (donepezil) should be used as follows:

• Dosage: Follow the dosage prescribed by your healthcare provider. It typically starts with a low dose that may be gradually increased based on your response to the medication.
• Administration:
  • Oral Tablet: Take the tablet by mouth, usually once a day, in the evening before bedtime. It can be taken with or without food.
  • Oral Disintegrating Tablet: Place the tablet on your tongue and let it dissolve. It can be taken with or without water.
• Consistency: Take Aricept at the same time every day to maintain consistent levels in your body.
• Missed Dose: If you miss a dose, take it as soon as you remember, but if it’s almost time for your next dose, skip the missed dose. Do not double up to make up for a missed dose.
• Storage: Store the medication at room temperature, away from moisture and heat. Keep it out of reach of children.
• Avoid: Do not stop taking Aricept or adjust your dosage without consulting your healthcare provider.

If you have any concerns or experience side effects, contact your healthcare provider for guidance.

Other uses for this medicine

While Aricept is primarily prescribed for Alzheimer’s disease, it may also be used for:

• Dementia: Aricept can be prescribed for dementia caused by conditions other than Alzheimer’s, such as Parkinson’s disease dementia or Lewy body dementia.
• Mild Cognitive Impairment (MCI): In some cases, it may be used for individuals with MCI who are at risk of developing Alzheimer’s disease.

What special precautions should I follow?

When using Aricept, consider the following precautions:

• Allergies: Inform your healthcare provider if you are allergic to donepezil or any other medications.
• Heart Conditions: Aricept can slow the heart rate (bradycardia). If you have a history of heart problems or a heart rhythm disorder, discuss this with your doctor.
• Liver or Kidney Issues: If you have liver or kidney disease, your dosage may need adjustment.
• Seizures: If you have a history of seizures or epilepsy, let your healthcare provider know.
• Medications: Inform your doctor of all other medications you are taking, including over-the-counter drugs, supplements, and herbal products, as they may interact with Aricept.
• Side Effects: Be aware of possible side effects such as nausea, diarrhea, muscle cramps, or insomnia. Report any severe or persistent side effects to your healthcare provider.
• Pregnancy and Breastfeeding: If you are pregnant, plan to become pregnant, or are breastfeeding, consult your healthcare provider to discuss the potential risks and benefits.
• Driving and Operating Machinery: Since Aricept can cause dizziness or drowsiness, be cautious when driving or operating machinery until you know how the medication affects you.

Always follow your healthcare provider’s instructions and report any concerns or changes in your condition.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Aricept. However, maintaining a balanced diet can help manage side effects like gastrointestinal discomfort. If you experience significant nausea or digestive issues, consult your healthcare provider for personalized advice.

What should I do if I forget a dose?

• Missed Dose: If you miss a dose, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose. Do not double up to make up for a missed dose.
• Regular Schedule: Try to take Aricept at the same time every day to help remember your dose and maintain consistent levels of the medication in your body.

What side effects can this medication cause?

Aricept (donepezil) can cause a range of side effects. Some of the more common side effects include:

• Nausea
• Diarrhea
• Loss of appetite
• Muscle cramps
• Fatigue
• Insomnia
• Dizziness
• Headache
• Vomiting

Less common but more serious side effects can include:

• Bradycardia (slow heart rate): This can cause dizziness, fainting, or lightheadedness.
• Gastrointestinal bleeding: Look for symptoms such as black or tarry stools or vomiting blood.
• Severe allergic reactions: Symptoms may include rash, itching, swelling, severe dizziness, or trouble breathing.
• Seizures: Especially if you have a history of seizure disorders.

If you experience severe or persistent side effects, or if you notice any symptoms that could indicate a serious reaction, contact your healthcare provider immediately.

What should I know about storage and disposal of this medication?

Storage and Disposal of Aredia:

Storage:

• Store Aricept at room temperature, between 59°F and 77°F (15°C and 25°C).
• Keep the medication in its original container, tightly closed, and protect it from moisture and heat.
• Store it out of reach of children.

Disposal:

• Do not flush Aricept down the toilet or pour it into a drain unless instructed to do so.
• If no take-back programs are available, dispose of the medication by following the instructions on the label or patient information provided by your pharmacist. Some communities have drug take-back programs or disposal kiosks.
• Alternatively, you can mix the medication with an undesirable substance (like used coffee grounds or cat litter), place it in a sealed bag or container, and throw it in the household trash.

In case of emergency/overdose

• Signs of Overdose: Symptoms of an overdose may include severe nausea, vomiting, diarrhea, muscle twitching, severe bradycardia (slow heart rate), seizures, and fainting.
• Actions: If you suspect an overdose, seek emergency medical attention immediately or call your local emergency number. You may also contact your local poison control center for guidance.

What other information should I know?

• Regular Monitoring: Regular follow-up appointments with your healthcare provider are important to monitor the effectiveness and side effects of Aricept.
• Medication Review: Keep your healthcare provider informed about all other medications and supplements you are taking to avoid interactions.
• Behavioral Changes: If you notice changes in mood, behavior, or cognitive function, inform your healthcare provider, as these may need to be addressed.
• Pregnancy and Breastfeeding: Discuss any plans to become pregnant or breastfeeding with your healthcare provider to understand the potential risks.
• Missed Doses: Always follow the advice for missed doses and do not double the dose to compensate for a missed one.

Always follow the instructions provided by your healthcare provider and consult them if you have any concerns or questions about your medication.