Why is this medication prescribed?

Anzemet is primarily prescribed to prevent and treat nausea and vomiting associated with chemotherapy, radiation therapy, and surgery. It is a type of antiemetic medication that works by blocking serotonin, a neurotransmitter that can trigger nausea and vomiting.

How should this medicine be used?

Here’s how to use Anzemet correctly:

• Dosage: Follow your doctor’s instructions regarding the dosage. Typically, it is taken as a single oral dose before chemotherapy, radiation, or surgery. For oral tablets, it is usually taken with or without food.
• Timing: Take Anzemet at the prescribed time, usually about 1 to 2 hours before the start of chemotherapy or radiation, or as directed by your doctor.
• Administration: If you are using the oral tablets, swallow them whole with a glass of water. Do not chew or crush the tablets.
• Missed Dose: If you miss a dose and it is close to the time for your next dose, skip the missed dose. Do not double up to make up for a missed dose.
• Side Effects: Be aware of potential side effects like headache, dizziness, constipation, or fatigue. Contact your doctor if you experience severe side effects or signs of an allergic reaction.

Always follow your healthcare provider’s instructions for use and consult them if you have any questions or concerns about taking Anzemet.

Other uses for this medicine

In addition to preventing and treating nausea and vomiting from chemotherapy, radiation therapy, and surgery, dolasetron (Anzemet) may also be used for:

• Postoperative Nausea and Vomiting: It can be prescribed to prevent and treat nausea and vomiting that occur after surgery.
• Gastroparesis: In some cases, it may be used off-label to help with symptoms of gastroparesis, a condition that affects the stomach’s ability to empty properly.

What special precautions should I follow?

Special Precautions to Follow for Anzemet:

• Allergies: Inform your healthcare provider if you are allergic to dolasetron or any other medications.
• Medical History: Provide your doctor with a complete medical history, especially if you have a history of heart problems, liver disease, or kidney issues.
• Heart Conditions: Dolasetron can cause changes in heart rhythm. If you have a history of heart conditions, your doctor may need to monitor you more closely while you are on this medication.
• Drug Interactions: Be aware of potential interactions with other medications, particularly other drugs that affect heart rhythm. Inform your doctor about all other medications you are taking, including over-the-counter drugs and supplements.
• Pregnancy and Breastfeeding: If you are pregnant, plan to become pregnant, or are breastfeeding, consult your healthcare provider to weigh the risks and benefits of using dolasetron.
• Side Effects: Monitor for any severe side effects, such as severe dizziness, fainting, or irregular heartbeat. Report these to your doctor immediately.

Always follow your healthcare provider’s instructions and consult them if you have any concerns or experience any unusual symptoms while taking Anzemet.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Anzemet. However, taking the medication with or without food is generally acceptable. Follow any specific instructions provided by your healthcare provider.

What should I do if I forget a dose?

• Timing: If you forget to take your dose and it is close to the time for your next dose, skip the missed dose. Do not take a double dose to make up for the missed one.
• Consult Your Doctor: If you are unsure about what to do if you miss a dose, or if you have missed multiple doses, contact your healthcare provider for guidance. They can provide specific advice based on your treatment plan.

What side effects can this medication cause?

Anzemet (dolasetron) can cause a range of side effects. Some of the more common and less severe ones include:

• Headache
• Dizziness
• Fatigue
• Constipation
• Diarrhea
• Dry mouth

Serious Side Effects: In some cases, more serious side effects can occur, including:

• Heart Rhythm Changes: Dolasetron can affect heart rhythm, potentially leading to irregular heartbeat (arrhythmia). Symptoms may include palpitations, chest pain, or fainting.
• Severe Allergic Reactions: Signs might include rash, itching, swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.
• Severe Drowsiness: In some cases, excessive drowsiness may occur, which can impair your ability to perform tasks that require alertness.
• Report Severe Side Effects: Contact your healthcare provider immediately if you experience severe side effects or signs of an allergic reaction.
• Routine Monitoring: Regular check-ups may be needed to monitor for side effects, especially if you have a history of heart problems or other health conditions.

Always consult your healthcare provider if you have concerns about side effects or experience any symptoms that worry you.

What should I know about storage and disposal of this medication?

Storage and Disposal of Anzemet:

Storage:

• Store Anzemet at room temperature, away from heat, moisture, and direct light. Typically, this means keeping it in a cool, dry place.
• Keep the medication in its original container, tightly closed to protect it from moisture and light.
• Keep Anzemet out of reach of children and pets to prevent accidental ingestion.

Disposal:

• Dispose of any unused or expired Anzemet properly. Do not flush it down the toilet or throw it in the trash unless instructed to do so.
• The best way to dispose of medications is through a drug take-back program. Many pharmacies and local waste disposal facilities offer these services.
• Alternatively, you can check the FDA’s website for specific disposal instructions or recommendations for your area.

In case of emergency/overdose

• Seek Immediate Medical Attention: If you suspect an overdose or experience severe symptoms, such as irregular heartbeat, severe dizziness, or loss of consciousness, seek emergency medical help immediately.
• Contact Poison Control: You can also contact your local poison control center for advice on what to do in the event of an overdose.

What other information should I know?

• Follow-Up: Regular follow-ups with your healthcare provider are important to ensure the medication is working as intended and to monitor for side effects.
• Medical Records: Keep a record of your medication and share this information with all your healthcare providers.
• Interactions: Always inform your healthcare provider about all other medications, supplements, and health conditions you have to avoid potential interactions.

Always adhere to the instructions provided by your healthcare provider and consult them if you have any additional questions or concerns.