WARNING

Taking Amlodipine and Benazepril together can pose certain risks:

• Low Blood Pressure: Both medications lower blood pressure, which can sometimes lead to dizziness, lightheadedness, or fainting.
• Kidney Problems: The combination can affect kidney function, potentially causing issues such as swelling or changes in urination.
• High Potassium Levels: Benazepril can increase potassium levels, and combined with Amlodipine, this risk is higher, which can lead to heart problems.
• Angioedema: A rare but serious risk with Benazepril, involving severe swelling of the face, lips, tongue, or throat.

Regular monitoring and consultation with a healthcare provider are essential to manage these risks effectively.

Why is this medication prescribed

Amlodipine and benazepril are often prescribed together to manage high blood pressure (hypertension) and to treat certain conditions related to cardiovascular health.  Amlodipine is a calcium channel blocker that helps relax and widen blood vessels, making it easier for the heart to pump blood and lowering blood pressure. Benazepril is an ACE (angiotensin-converting enzyme) inhibitor that helps relax blood vessels by blocking the formation of a substance that narrows blood vessels.

How should this medicine be used?

Here are some general guidelines for using this combination:

• Dosage: Follow your healthcare provider’s instructions on the dosage. It’s important to take the medication exactly as prescribed.
• Monitoring: Regular monitoring of blood pressure and kidney function is important. Your healthcare provider will likely check your blood pressure regularly to ensure the combination is working effectively and to monitor for any side effects.
• Side Effects: Be aware of potential side effects, which can include dizziness, lightheadedness, or swelling. Report any severe or persistent side effects to your healthcare provider.
• Lifestyle: In addition to medication, maintaining a healthy lifestyle (including a balanced diet, regular exercise, and avoiding excessive salt intake) is important for managing blood pressure.
• Interactions: Inform your healthcare provider of any other medications or supplements you are taking, as there can be interactions.

Always consult your healthcare provider for personalized advice and to address any concerns specific to your health condition.

Other uses for this medicine

• Heart Failure: This combination can also help manage symptoms of heart failure by reducing the workload on the heart and improving its efficiency.
• Chronic Kidney Disease: In some cases, this combination may be used to manage blood pressure in people with chronic kidney disease, as ACE inhibitors can help protect kidney function.

What special precautions should I follow?

Special Precautions:

• Monitor Blood Pressure: Regularly check your blood pressure to ensure it is within the target range and to avoid potential complications of too low blood pressure.
• Kidney Function: Monitor kidney function with regular blood tests, as both medications can affect kidney function.
• Electrolyte Levels: Keep an eye on potassium levels. ACE inhibitors like Benazepril can increase potassium levels, which can be problematic if too high.
• Avoid Certain Supplements and Medications: Some supplements and medications can interact with this combination, so inform your healthcare provider about all the medications and supplements you’re taking.
• Hydration: Maintain adequate hydration, especially if you have a condition that affects fluid balance or if you’re taking diuretics alongside these medications.
• Pregnancy and Breastfeeding: Avoid use during pregnancy as it can harm the fetus. Discuss alternatives with your healthcare provider if you’re pregnant or breastfeeding.

Always follow your healthcare provider’s instructions and report any unusual symptoms or side effects promptly.

What special dietary instructions should I follow?

• Sodium Intake: Reduce sodium (salt) intake to help manage blood pressure effectively. Follow any specific dietary recommendations provided by your healthcare provider.
• Potassium: As mentioned, avoid excessive potassium intake from foods or supplements unless your doctor advises otherwise.

What should I do if I forget a dose?

• Timing: If you miss a dose of Amlodipine or Benazepril, take it as soon as you remember.
• Skip If Near Next Dose: If it’s almost time for your next dose, skip the missed dose; do not double up to make up for a missed dose.
• Consult Your Doctor: Contact your healthcare provider or pharmacist for specific instructions tailored to your situation.

What side effects can this medication cause?

Amlodipine and benazepril, when used together, can cause a range of side effects. Here’s a rundown:

Common Side Effects:

• Dizziness or lightheadedness
• Fatigue
• Headache
• Swelling (edema) in the hands, feet, or ankles
• Cough (more common with benazepril)
• Nausea or stomach pain

Less Common but Serious Side Effects:

• Low blood pressure (hypotension)
• Rapid or irregular heartbeat (palpitations)
• Severe allergic reactions, including rash, itching, or swelling of the face, tongue, or throat
• Kidney problems, such as changes in urine output or blood in the urine
• Angioedema, which is a serious swelling of the deeper layers of the skin, often around the eyes and lips
• Liver issues, which might present as jaundice (yellowing of the skin or eyes)
• Muscle pain or weakness, which could be a sign of a rare but serious condition called rhabdomyolysis

If you experience any severe or unusual symptoms, it’s important to contact your healthcare provider promptly.

What should I know about storage and disposal of this medication?

Amlodipine and Benazepril:

• Storage: Store both medications at room temperature, away from moisture and heat. Typically, a dry place with a temperature between 68°F to 77°F (20°C to 25°C) is recommended.
• Disposal: Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Instead, use a drug take-back program if available, or follow local disposal guidelines. You can also check with your pharmacist for advice on safe disposal methods.

In case of emergency/overdose

• Seek Medical Help: Contact emergency services or go to the nearest emergency room if an overdose is suspected.
• Poison Control: You can also contact the Poison Control Center for guidance.
• Medication Details: Provide the name of the medication, the dosage taken, and the time of ingestion.
• Symptoms: Describe any symptoms experienced to help medical professionals assess the situation.

What other information should I know?

• Regular Monitoring: Regular check-ups with your healthcare provider are important to monitor blood pressure, kidney function, and overall health while on these medications.
• Lifestyle Changes: Adhere to lifestyle changes recommended by your doctor, such as dietary modifications and exercise, to improve the effectiveness of the medication.
• Interactions: Be aware of potential drug interactions with other medications, including over-the-counter drugs and supplements.

Always follow your healthcare provider’s instructions and consult them for personalized advice and information regarding your specific situation.