Why is this medication prescribed?

Acamprosate is prescribed to help people with alcohol dependence maintain abstinence from drinking. Acamprosate works by affecting neurotransmitter systems in the brain, particularly by modulating glutamate and gamma-aminobutyric acid (GABA) activity. This helps to reduce cravings and the desire to drink alcohol, making it easier for individuals to stay abstinent and support their recovery. It’s typically used as part of a comprehensive treatment plan that includes counseling and support.

How should this medicine be used?

Acamprosate is usually taken orally in tablet form. Here are some general guidelines for its use:

• Dosage: The typical dosage is 666 mg three times a day, but your doctor will determine the exact amount based on your specific needs and medical condition.
• Administration: The tablets should be swallowed whole with water, and they can be taken with or without food.
• Consistency: It’s important to take acamprosate at the same times each day to maintain even levels in your system.
• Adherence: Follow your doctor’s instructions precisely and don’t stop taking the medication without consulting them first, even if you feel better.
• Monitoring: Regular follow-ups with your healthcare provider are important to monitor your progress and any potential side effects.

Always discuss with your healthcare provider for personalized instructions and any questions about the medication.

Other uses for this medicine

Acamprosate is primarily used for treating alcohol dependence, but it is not typically used for other conditions.

What special precautions should I follow?

Special precautions for Acamprosate include:

• Kidney Function: Acamprosate is excreted through the kidneys, so it should be used with caution in individuals with kidney problems. Your doctor may adjust the dose based on your kidney function.
• Pregnancy and Breastfeeding: The safety of acamprosate during pregnancy and breastfeeding isn’t well-established, so it should be used only if clearly needed and prescribed by a healthcare provider.
• Allergies: Inform your doctor if you have any known allergies or if you’ve had adverse reactions to other medications.
• Other Medications: Tell your healthcare provider about all other medications you are taking, including over-the-counter drugs and supplements, as there could be interactions.
• Mental Health: While rare, if you experience any new or worsening mental health issues, such as depression or suicidal thoughts, inform your healthcare provider immediately.

Always follow your healthcare provider’s advice and guidance when using acamprosate.

What special dietary instructions should I follow?

• Food and Drink: There are generally no specific dietary restrictions with acamprosate. However, it’s a good idea to maintain a balanced diet and stay hydrated.
• Alcohol: You should avoid alcohol while taking acamprosate. Drinking alcohol can counteract the medication’s effects and potentially lead to serious side effects

What should I do if I forget a dose?

• Missed Dose: If you forget a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular schedule.
• Do Not Double Up: Avoid taking two doses at once to make up for a missed dose, as this can increase the risk of side effects.
• Contact Your Doctor: If you frequently forget doses or have concerns about managing your medication, consult your healthcare provider for advice.

What side effects can this medication cause?

Acamprosate can cause side effects, although not everyone experiences them. Common side effects include:

• Diarrhea: This is one of the most frequent side effects. It’s often mild but can be bothersome.
• Nausea: Some people might feel queasy or experience an upset stomach.
• Abdominal Pain: Discomfort in the stomach area can occur.
• Headache: Headaches are possible, though not too common.
• Dizziness: Feeling lightheaded or dizzy may happen.
• Fatigue: You might feel unusually tired or lethargic.

Less common but more serious side effects include:

• Severe Allergic Reactions: Symptoms like rash, itching, swelling, severe dizziness, or trouble breathing could indicate a serious allergic reaction and require immediate medical attention.
• Suicidal Thoughts or Behaviors: Although rare, some individuals may experience changes in mood or behavior. If you notice any signs of depression or suicidal thoughts, contact your healthcare provider right away.

Most people tolerate acamprosate well, but if you experience any persistent or severe side effects, it’s important to reach out to your healthcare provider for guidance and possible adjustment of your treatment.

What should I know about storage and disposal of this medication?

Storage and Disposal:

• Storage:
  • Temperature: Store acamprosate at room temperature, typically between 68°F and 77°F (20°C to 25°C).
  • Environment: Keep it in a dry place, away from moisture and direct light.
  • Container: Store it in its original container, tightly closed to protect from moisture.
• Disposal:
  • Do Not Flush: Do not flush acamprosate down the toilet or pour it into a drain unless specifically instructed to do so.
  • Drug Take-Back Programs: Check if your community has a drug take-back program or a pharmacy disposal service for proper disposal.
  • Household Disposal: If no take-back programs are available, you can dispose of acamprosate in your household trash, but it’s best to mix it with an undesirable substance (like used coffee grounds or cat litter) and place it in a sealed bag or container to prevent accidental ingestion.

In case of emergency/overdose

• Overdose Symptoms: Symptoms of an overdose might include severe diarrhea, nausea, or abdominal pain.
• Emergency Action: If you suspect an overdose or experience severe symptoms, seek immediate medical attention or call poison control.
• Emergency Number: In the U.S., you can call the Poison Help Line at 1-800-222-1222 or go to the nearest emergency room.

What other information should I know?

• Regular Monitoring: Attend regular follow-up appointments with your healthcare provider to monitor your progress and any side effects.
• Medication Interactions: Keep your healthcare provider informed about all medications you are taking, including over-the-counter drugs and supplements, as they could interact with acamprosate.
• Missed Dose: If you miss a dose, follow the guidelines for taking it as soon as you remember or skipping it if it’s nearly time for your next dose.

Always follow your healthcare provider’s specific instructions and consult them if you have any questions or concerns about your medication.