WARNING

Xopenex HFA (levalbuterol) is a medication commonly prescribed to treat bronchospasm in people with reversible obstructive airway disease, such as asthma. Like any medication, Xopenex HFA comes with potential risks and side effects. It’s important to note that individual responses to medications can vary, and not everyone will experience these effects. Here are some potential risks associated with Xopenex HFA:

• Common Side Effects: These may include headache, tremors, nervousness, dizziness, nausea, and throat irritation.
• Cardiovascular Effects: Levalbuterol, the active ingredient in Xopenex HFA, can have cardiovascular effects, including an increased heart rate (tachycardia) and elevated blood pressure. People with pre-existing cardiovascular conditions may be more susceptible to these effects.
• Hypersensitivity Reactions: Some individuals may experience allergic reactions to Xopenex HFA, such as rash, itching, swelling, severe dizziness, or difficulty breathing. Seek medical attention immediately if you observe any signs of a serious allergic reaction.
• Paradoxical Bronchospasm: In some cases, bronchospasm (contraction of the airways) may occur as a paradoxical reaction to Xopenex HFA. If this happens, discontinue use and seek medical attention.
• Electrolyte Imbalance: Beta-agonist medications like Xopenex HFA can potentially lead to changes in serum potassium levels. This is more likely to occur in people with conditions such as hypokalemia (low potassium levels) or in conjunction with drugs that can affect potassium levels.
• Diabetes: Levalbuterol may affect blood glucose levels, and caution is advised in individuals with diabetes.
• Use in Pregnancy and Breastfeeding: The safety of Xopenex HFA during pregnancy and breastfeeding is not well-established. Consult with a healthcare provider to weigh the potential benefits against risks.
• Drug Interactions: Xopenex HFA may interact with other medications, and it’s important to inform your healthcare provider about all the drugs you are taking.

It’s crucial to use Xopenex HFA only as prescribed by a healthcare professional and to promptly report any unusual or severe side effects. If you have concerns or experience adverse effects, consult your healthcare provider for guidance. This information is not exhaustive, and specific risks may vary based on individual health conditions and medical history. Always follow the guidance of your healthcare provider and read the medication’s accompanying information.

Why is this medication prescribed?

Xopenex HFA (levalbuterol) is a prescription medication used to treat or prevent bronchospasm in people with reversible obstructive airway disease. It is primarily prescribed for individuals with conditions such as asthma and chronic obstructive pulmonary disease (COPD). The active ingredient in Xopenex HFA, levalbuterol, is a bronchodilator that helps to relax the muscles in the airways, making it easier to breathe.

How should this medicine be used?

Here are some general guidelines for using Xopenex HFA:

• Dosage: The dosage of Xopenex HFA can vary depending on factors such as the individual’s age, medical condition, and response to treatment. It is important to follow the prescribed dosage provided by the healthcare provider.
• Administration: Xopenex HFA is an inhalation aerosol and is administered using an inhaler device. The inhaler delivers a measured dose of medication directly into the lungs.
• Instructions for Use:
  • Shake the inhaler well before each use.
  • If it’s the first time you are using the inhaler or if it has not been used for a while, prime it by spraying a few test sprays into the air until an aerosol cloud is visible.
  • Breathe out fully, place the inhaler in your mouth, and close your lips around the mouthpiece.
  • While pressing down on the inhaler, breathe in deeply and slowly through your mouth to ensure the medication reaches the lungs.
  • Hold your breath for a few seconds to allow the medication to be absorbed.
  • If a second inhalation is prescribed, wait for about a minute before repeating the process.
• Frequency: Follow the prescribed dosing schedule. Typically, Xopenex HFA is used every 4 to 6 hours as needed. However, your healthcare provider will determine the appropriate frequency based on your specific condition.
• Cleaning: Keep the inhaler clean by wiping the mouthpiece with a clean, dry tissue or cloth.

It’s crucial to use Xopenex HFA exactly as prescribed by your healthcare provider. If you have any questions about its use, dosing, or potential side effects, consult with your healthcare professional for guidance. Additionally, regular follow-ups with your healthcare provider are important to monitor your response to the medication and make any necessary adjustments to your treatment plan.

Other uses for this medicine

While Xopenex HFA (levalbuterol) is primarily prescribed for the treatment of bronchospasm associated with conditions like asthma and chronic obstructive pulmonary disease (COPD), it’s important to note that medications may sometimes be used off-label for other purposes. “Off-label” use means using a drug to treat a condition or in a manner not specifically approved by regulatory authorities.

What special precautions should I follow?

As for special precautions, here are some important considerations:

• Allergies: Inform your healthcare provider about any allergies you may have, especially if you have had an allergic reaction to levalbuterol or any other medications.
• Medical History: Provide a detailed medical history, including any heart problems, high blood pressure, diabetes, or other conditions that may impact the use of Xopenex HFA.
• Current Medications: Inform your healthcare provider about all prescription and over-the-counter medications, vitamins, and herbal supplements you are currently taking. Certain medications may interact with Xopenex HFA.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Xopenex HFA with your healthcare provider.
• Cardiovascular Effects: Levalbuterol can have cardiovascular effects, so it’s important to use it with caution in individuals with cardiovascular diseases, such as heart rhythm disorders or coronary artery disease.
• Diabetes: Levalbuterol can affect blood sugar levels, so individuals with diabetes should monitor their blood sugar closely while using this medication.
• Hypersensitivity Reactions: Seek medical attention if you experience symptoms of a hypersensitivity reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing.
• Worsening Symptoms: If your symptoms worsen or if you find that you need to use Xopenex HFA more frequently than prescribed, contact your healthcare provider.

Always follow the instructions provided by your healthcare provider and the medication’s packaging. If you have any questions or concerns about the use of Xopenex HFA or its potential off-label uses, consult with your healthcare professional for personalized guidance.

What special dietary instructions should I follow?

Xopenex HFA generally does not have specific dietary restrictions. However, maintaining a balanced diet and staying well-hydrated is generally beneficial for overall health and may complement your asthma management.

What should I do if I forget a dose?

• If you miss a dose of Xopenex HFA, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
• Do not double the dose to make up for a missed one.
• If you are unsure about what to do, consult with your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Xopenex HFA (levalbuterol) may cause side effects in some individuals. It’s important to note that not everyone will experience these side effects, and they can vary in severity. Common side effects are generally mild and may include:

• Nervousness or Tremor: Some people may experience mild nervousness or tremors, which are common side effects of bronchodilator medications.
• Headache: Headaches are reported by some individuals using Xopenex HFA.
• Dizziness: A feeling of dizziness or lightheadedness can occur.
• Throat Irritation or Dry Mouth: Inhalers can sometimes cause irritation or dryness in the throat.
• Palpitations: Some individuals may experience a sensation of rapid or irregular heartbeat.
• Coughing: Coughing may occur as a result of irritation in the airways.
• Nausea: Some people may experience mild nausea.

These side effects are often transient and may diminish with continued use. However, if any of these effects persist or worsen, it’s important to inform your healthcare provider.

Serious side effects are less common but may include:

• Chest Pain: Seek medical attention if you experience chest pain or discomfort.
• Irregular Heartbeat: Report any changes in your heartbeat to your healthcare provider.
• High Blood Pressure: In rare cases, levalbuterol can cause an increase in blood pressure.
• Allergic Reactions: Seek immediate medical attention if you experience symptoms of a serious allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing.

It’s crucial to follow the prescribed dosage and instructions provided by your healthcare provider. If you are concerned about any side effects or have questions about the use of Xopenex HFA, consult with your healthcare professional. They can provide personalized guidance based on your medical history and individual health needs.

What should I know about storage and disposal of this medication?

Storage and Disposal of Xopenex HFA:

• Storage:
  • Store Xopenex HFA (levalbuterol inhalation aerosol) at room temperature, away from moisture, heat, and direct light.
  • Keep the inhaler canister away from high temperatures (e.g., do not store in a car during hot weather).
  • Do not puncture the canister or expose it to open flame or high heat.
• Disposal:
  • Do not throw the Xopenex HFA canister into a fire or incinerator.
  • Do not puncture or open the canister.
  • Dispose of the inhaler responsibly by following local regulations or guidelines for the disposal of medication.

In case of emergency/overdose

• In case of an overdose or emergency, contact your local poison control center or emergency room immediately.
• Symptoms of overdose may include chest pain, fast or irregular heartbeats, nervousness, headache, tremor, dry mouth, dizziness, or seizure.

What other information should I know?

• Usage Instructions:
  • Follow the prescribed dosage and administration instructions provided by your healthcare provider.
  • Shake the inhaler well before each use.
  • Inhale the medication as directed, usually every 4 to 6 hours as needed.
• Medical History: Inform your healthcare provider about your medical history, especially if you have heart problems, high blood pressure, diabetes, or other medical conditions.
• Allergies: Inform your doctor of any allergies you may have, especially to levalbuterol or other medications.
• Side Effects: Be aware of potential side effects and report any unusual or severe reactions to your healthcare provider.
• Regular Check-ups: Regularly check in with your healthcare provider to monitor your response to the medication and adjust the treatment plan as needed.

Always follow your healthcare provider’s advice and instructions regarding the use, storage, and disposal of Xopenex HFA. If you have any questions or concerns, consult with your healthcare professional for personalized guidance.