Why is this medication prescribed?

Xofluza (generic name: baloxavir marboxil) is an antiviral medication used for the treatment of acute uncomplicated influenza (flu) in people 12 years of age and older. It is not a substitute for the flu vaccine, but rather a treatment option for those who have already contracted the flu.

Xofluza works by inhibiting a crucial enzyme in the replication of the influenza virus, which helps to reduce the duration and severity of flu symptoms.

How should this medicine be used?

Here are the general guidelines for using Xofluza:

• Dosage: For individuals 12 years of age and older: The typical dose is a single oral dose of 40 mg. It is usually taken with or without food as soon as possible (within 48 hours) after the onset of flu symptoms.
• Administration: Xofluza is available in tablet form, and it should be swallowed whole with water. It is essential to follow the prescribed dosage and administration instructions provided by the healthcare provider.
• Timing: It is crucial to start Xofluza as soon as possible after the onset of flu symptoms (within 48 hours) for optimal effectiveness.
• Avoidance of Certain Substances: Xofluza should not be taken with dairy products, calcium-fortified beverages, antacids, or oral supplements containing calcium, iron, magnesium, selenium, aluminum, or zinc. These can interfere with the absorption of Xofluza.
• Follow-Up: Patients should follow up with their healthcare provider if they have not improved within a few days or if their symptoms worsen.
• Precautions: Inform your healthcare provider about any other medications, supplements, or medical conditions you have before starting Xofluza to avoid potential interactions or complications.

It’s crucial to note that Xofluza is specifically for the treatment of influenza and is not a substitute for the flu vaccine, which is recommended for preventing influenza.

As always, individuals should consult with their healthcare provider for personalized advice based on their health status and any specific conditions they may have. The information provided here is for general informational purposes and should not be considered as medical advice.

Other uses for this medicine

Xofluza (baloxavir marboxil) is primarily indicated for the treatment of acute uncomplicated influenza in individuals aged 12 years and older. It is important to note that medications may receive additional approved uses or indications after my last update. Therefore, it’s crucial to consult the latest medical resources or a healthcare professional for the most current information on Xofluza.

What special precautions should I follow?

As for special precautions when using Xofluza, consider the following:

• Pregnancy and Breastfeeding: Pregnant or breastfeeding individuals should discuss the risks and benefits of using Xofluza with their healthcare provider before taking the medication.
• Allergies: Inform your healthcare provider about any known allergies to baloxavir marboxil or any other components of Xofluza.
• Interactions with Other Medications: Certain medications and substances may interact with Xofluza, potentially affecting its efficacy or leading to adverse effects. It’s essential to inform your healthcare provider about all the medications, supplements, and herbal products you are currently taking.
• Timing of Other Medications: Xofluza should not be taken with dairy products, calcium-fortified beverages, antacids, or oral supplements containing calcium, iron, magnesium, selenium, aluminum, or zinc. These substances can interfere with the absorption of Xofluza. If you need to take these substances, it is advised to wait at least 2 hours before or after taking Xofluza.
• Pediatric Use: Xofluza is approved for use in individuals aged 12 years and older. Safety and efficacy in younger populations have not been established.
• Liver or Kidney Conditions: Individuals with pre-existing liver or kidney conditions may require special monitoring or dosage adjustments. It’s important to discuss your medical history with your healthcare provider.
• Adverse Reactions: Be aware of potential side effects of Xofluza, such as diarrhea, bronchitis, nausea, and headache. If you experience any unusual or severe symptoms, contact your healthcare provider.
• Follow-Up: Follow up with your healthcare provider if your symptoms do not improve within a few days or if they worsen after taking Xofluza.

Always follow your healthcare provider’s instructions and guidance for the use of Xofluza, and do not self-prescribe or alter the dosage without consulting them. This information is a general guideline and not a substitute for professional medical advice. If you have specific concerns or questions about Xofluza, consult with a healthcare professional for personalized advice based on your health status.

What special dietary instructions should I follow?

For Xofluza (baloxavir marboxil), there are specific dietary instructions related to its absorption. Here are important considerations:

• Xofluza should not be taken with dairy products, calcium-fortified beverages, antacids, or oral supplements containing calcium, iron, magnesium, selenium, aluminum, or zinc.
• These substances can interfere with the absorption of Xofluza. If you need to take these substances, it is generally recommended to wait at least 2 hours before or after taking Xofluza.

What should I do if I forget a dose?

Regarding what to do if you forget a dose:

• Take It as Soon as Possible: If you forget to take a dose of Xofluza, take it as soon as you remember.
• Skip the Missed Dose if it’s Almost Time for the Next Dose: If it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
• Do Not Double Dose: Do not take a double dose to make up for a missed one. Taking more than the prescribed amount can increase the risk of side effects without providing additional benefits.

What side effects can this medication cause?

Xofluza (baloxavir marboxil) may cause side effects in some individuals. It’s important to note that not everyone will experience these side effects, and some people may experience side effects that are not listed. Common side effects of Xofluza include:

• Diarrhea: Diarrhea is one of the more common side effects reported by individuals taking Xofluza.
• Bronchitis: Respiratory symptoms such as bronchitis have been reported as side effects.
• Nausea: Some individuals may experience nausea after taking Xofluza.
• Headache: Headache is another reported side effect.
• Fatigue: Some people may feel tired or fatigued.
• Abnormal Liver Function Tests: Changes in liver function tests may occur, but serious liver problems are rare.

It’s important to contact your healthcare provider if you experience any side effects, especially if they are severe, persistent, or worsening over time. Additionally, if you have any signs of an allergic reaction (such as rash, itching, swelling, severe dizziness, or difficulty breathing), seek medical attention immediately.

This list does not cover all possible side effects, and there may be other side effects not mentioned here. Individual responses to medications can vary, so it’s crucial to discuss any concerns or symptoms with your healthcare provider. They can provide personalized guidance based on your health history and specific circumstances.

Remember that the benefits of taking Xofluza in treating influenza symptoms typically outweigh the risks of potential side effects for most individuals.

What should I know about storage and disposal of this medication?

Storage and Disposal of Xofluza:

• Storage:
  • Store Xofluza at room temperature, away from moisture and heat.
  • Keep it in its original packaging or container.
• Disposal:
  • Dispose of any unused or expired medication according to local regulations or guidelines.
  • Do not flush medications down the toilet unless instructed to do so. Instead, use a drug take-back program or follow specific disposal instructions provided by your healthcare provider or local pharmacy.

In case of emergency/overdose

In the case of an overdose or emergency, contact your local poison control center (1-800-222-1222 in the United States) or emergency room immediately. Symptoms of overdose may include increased or severe side effects.

What other information should I know?

• Follow Healthcare Provider’s Instructions: Take Xofluza exactly as prescribed by your healthcare provider. Do not alter the dosage without consulting your healthcare provider.
• Inform Healthcare Provider: Inform your healthcare provider about all medications, supplements, and herbal products you are taking, as well as any pre-existing medical conditions.
• Avoid Certain Substances: Avoid taking Xofluza with dairy products, calcium-fortified beverages, antacids, or oral supplements containing calcium, iron, magnesium, selenium, aluminum, or zinc, as they can interfere with its absorption.
• Symptom Improvement: If your flu symptoms do not improve within a few days or if they worsen, contact your healthcare provider.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Xofluza with your healthcare provider.
• Allergic Reactions: Seek medical attention immediately if you experience signs of an allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing.
• Regular Check-ups: Attend regular check-ups with your healthcare provider to monitor your response to the medication and address any concerns.
• Complete Treatment: Complete the full course of Xofluza, even if you start feeling better before the medication is finished.

Always follow the advice and instructions provided by your healthcare provider and the information provided on the medication’s label. If you have any questions or concerns, don’t hesitate to reach out to your healthcare provider for clarification and guidance.